Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   GWQ54_RS28445 Genome accession   NZ_CP070373
Coordinates   6423579..6426593 (-) Length   1004 a.a.
NCBI ID   WP_167154039.1    Uniprot ID   -
Organism   Streptomyces sp. MBT27     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 6418579..6431593
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GWQ54_RS28420 - 6418737..6419633 (-) 897 WP_240361858.1 hypothetical protein -
  GWQ54_RS28425 - 6419630..6420238 (-) 609 WP_161244426.1 papain-like cysteine protease family protein -
  GWQ54_RS28430 - 6420478..6421401 (+) 924 WP_161244425.1 hypothetical protein -
  GWQ54_RS28435 - 6421423..6421851 (-) 429 WP_161244424.1 Rieske (2Fe-2S) protein -
  GWQ54_RS28440 - 6422032..6422925 (+) 894 WP_167154041.1 carbohydrate kinase -
  GWQ54_RS28445 uvrA 6423579..6426593 (-) 3015 WP_167154039.1 excinuclease ABC subunit UvrA Machinery gene
  GWQ54_RS28450 - 6426810..6427499 (+) 690 WP_167154037.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  GWQ54_RS28455 - 6427521..6428177 (+) 657 WP_167154035.1 MBL fold metallo-hydrolase -
  GWQ54_RS28460 - 6428412..6429698 (+) 1287 WP_167156347.1 MFS transporter -
  GWQ54_RS28465 - 6429719..6430699 (-) 981 WP_161244846.1 TerC family protein -

Sequence

Protein


Download         Length: 1004 a.a.        Molecular weight: 110023.34 Da        Isoelectric Point: 8.0991

>NTDB_id=474081 GWQ54_RS28445 WP_167154039.1 6423579..6426593(-) (uvrA) [Streptomyces sp. MBT27]
MADRLIVRGAREHNLKNVSLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSSYARQFLGQMDKPDVDFIEGL
SPAVSIDQKSTSRNPRSTVGTITEVYDYLRLLFARIGKPHCPECRRPISRQSPQAIVDKVLELPEGSRFQVLSPLVRERK
GEFVDLFADLQTKGYSRARVDGETIQLAEPPKLKKQEKHTIEVVIDRLTVKEGAKRRLTDSVETALGLSGGMVVLDFVDL
AADDPERERMYSEHLYCPYDDLSFEELEPRSFSFNSPFGACPDCTGIGTRMEVDPDLIIPDEDKSLDEGAVSPWSLGHTK
DYFARLVGALAGELGFRTDIPWAGLPQRAKKALLYGHKTQIEVRYRNRYGRERAYTTAFEGAVPFVKRRHSEAETDGARE
RFEGYMREVPCPTCEGTRLKPLVLAVTVMERSIAEVAAMSISDCADFLAKLKLNSRDKKIAERVLKEVNERLKFLVDVGL
DYLSLNRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNHRLIETLVRLRDMGNTLIVVEHDEDTIKVAD
WVVDIGPGAGEHGGKVVHSGPLKQLLSNKESMTGQYLAGKRSIPLPDVRRPVDPARRLTVHGAKENNLRDIDVSFPLGVL
TAVTGVSGSGKSTLVNDILYTHLARELNGARSVPGRHTRVDGDDLVDKVVHVDQSPIGRTPRSNPATYTGVFDHVRRLFA
ETMEAKVRGYLPGRFSFNVKGGRCENCSGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKSIAEVLDMPIEEG
LEFFEAVPTIARHLRTLNEVGLGYVRLGQSAPTLSGGEAQRVKLASELQKRSTGRTVYVLDEPTTGLHFEDISKLIKVLS
GLVDKGNSVIVIEHNLDVIKTADWVIDMGPEGGNGGGLVIAEGTPEEVASEPASHTGKFLRDILGADRISDAASSPGRKS
AKRAAPAKKAASAAKAAPAARKAASAAATKKAAPAKKATRARKA

Nucleotide


Download         Length: 3015 bp        

>NTDB_id=474081 GWQ54_RS28445 WP_167154039.1 6423579..6426593(-) (uvrA) [Streptomyces sp. MBT27]
GTGGCCGACCGTCTCATCGTCCGTGGCGCGCGCGAGCACAACCTCAAGAACGTCTCGCTCGACCTGCCGCGCGATTCCCT
CATCGTCTTCACGGGTCTTTCCGGGTCGGGCAAGTCCTCGCTCGCCTTCGACACGATCTTCGCCGAGGGCCAGCGCCGGT
ACGTCGAGTCGCTGTCCTCGTACGCCCGCCAGTTCCTCGGCCAGATGGACAAGCCGGACGTCGACTTCATCGAAGGACTG
TCGCCCGCCGTCTCCATCGACCAGAAGTCGACCTCGCGCAACCCGCGCTCCACGGTCGGCACCATCACCGAGGTCTACGA
CTACCTGCGTCTGCTGTTCGCGCGCATCGGCAAGCCGCACTGCCCCGAGTGCCGCAGGCCCATCTCGCGCCAGTCGCCCC
AGGCCATCGTCGACAAGGTGCTCGAACTGCCCGAGGGCAGCCGCTTCCAGGTGCTCTCGCCGCTGGTCCGTGAGCGCAAG
GGCGAGTTCGTCGACCTGTTCGCCGACCTCCAGACCAAGGGCTACAGCCGGGCCCGGGTCGACGGCGAGACCATCCAGCT
CGCCGAGCCGCCCAAGCTGAAGAAGCAGGAGAAGCACACCATCGAGGTGGTCATCGACCGCCTCACGGTGAAGGAGGGCG
CCAAGCGCCGCCTCACCGACTCGGTGGAGACCGCGCTCGGCCTGTCCGGCGGCATGGTCGTGCTCGACTTCGTCGACCTG
GCGGCCGACGACCCCGAGCGCGAGCGGATGTACTCGGAGCACCTGTACTGCCCGTACGACGACCTCTCCTTCGAGGAGCT
GGAGCCCCGCTCCTTCTCCTTCAACTCGCCGTTCGGCGCCTGCCCCGACTGCACCGGCATCGGCACGCGCATGGAGGTCG
ACCCCGACCTGATCATCCCGGACGAGGACAAGTCCCTGGACGAGGGCGCGGTCTCGCCGTGGTCGCTCGGCCACACCAAG
GACTACTTCGCCCGTCTGGTGGGGGCGCTCGCCGGTGAGCTGGGCTTCCGCACCGACATCCCCTGGGCCGGCCTTCCGCA
GCGCGCCAAGAAGGCGCTCCTGTACGGCCACAAGACGCAGATCGAGGTCCGCTACCGCAACCGGTACGGGCGCGAGCGCG
CGTACACCACCGCCTTCGAGGGCGCGGTGCCGTTCGTCAAGCGGCGCCACTCCGAGGCGGAGACCGACGGCGCGCGCGAG
CGCTTCGAGGGCTACATGCGCGAGGTGCCCTGCCCCACCTGTGAGGGCACGCGCCTGAAGCCGCTGGTGCTCGCGGTCAC
CGTGATGGAGCGGTCCATCGCCGAGGTCGCCGCGATGTCGATCAGCGACTGCGCGGACTTCCTGGCGAAGCTCAAGCTCA
ACAGCCGCGACAAGAAGATCGCCGAGCGGGTCCTGAAGGAGGTCAACGAGCGGCTGAAGTTCCTGGTCGACGTCGGCCTC
GACTACCTCTCGCTCAACCGCGCGGCCGGCACGCTCTCCGGCGGCGAGGCCCAGCGCATCCGGCTCGCCACCCAGATCGG
CTCCGGCCTGGTCGGCGTGCTCTACGTCCTGGACGAGCCCTCGATCGGGCTGCACCAGCGCGACAACCACCGTCTGATCG
AGACGCTGGTCCGCCTGCGCGACATGGGCAACACCCTGATCGTCGTCGAGCACGACGAGGACACCATCAAGGTGGCCGAC
TGGGTCGTCGACATCGGCCCCGGCGCCGGTGAGCACGGCGGAAAGGTCGTCCACAGCGGTCCGTTGAAGCAGCTGCTCAG
CAACAAGGAGTCGATGACGGGGCAGTACCTCGCGGGCAAGCGGTCGATCCCGCTGCCCGACGTGCGCCGTCCCGTCGACC
CCGCGCGCCGGCTCACCGTGCACGGCGCGAAGGAGAACAACCTCCGCGACATCGACGTCTCGTTCCCCCTCGGTGTGCTG
ACCGCCGTCACGGGCGTCTCCGGGTCGGGCAAGTCGACGCTGGTCAACGACATCCTCTACACGCACCTGGCGCGCGAGCT
GAACGGGGCGCGCAGCGTGCCGGGCCGGCACACCCGGGTCGACGGGGACGACCTGGTCGACAAGGTCGTGCACGTCGACC
AGTCGCCGATCGGCCGCACCCCGCGGTCCAACCCGGCGACGTACACCGGCGTCTTCGACCACGTCCGCAGGCTGTTCGCC
GAGACGATGGAGGCGAAGGTCCGGGGTTACCTGCCGGGCCGCTTCTCCTTCAACGTCAAGGGCGGCCGCTGCGAGAACTG
CTCGGGCGACGGCACGATCAAGATCGAGATGAACTTCCTGCCGGACGTGTACGTCCCCTGCGAGGTCTGCCACGGGGCGC
GCTACAACCGGGAGACCCTGGAGGTCCACTACAAGGGCAAGTCCATCGCCGAGGTCCTGGACATGCCGATCGAGGAGGGC
CTGGAGTTCTTCGAGGCCGTTCCGACGATCGCCCGTCACCTGCGGACGCTGAACGAGGTCGGGCTCGGCTACGTCCGGCT
CGGGCAGTCCGCGCCGACCCTGTCGGGTGGTGAGGCGCAGCGCGTCAAGCTGGCCTCCGAGCTGCAGAAGCGGTCCACGG
GCCGCACGGTGTACGTCCTCGACGAGCCCACCACCGGGCTCCACTTCGAGGACATCTCGAAGCTGATCAAGGTGCTTTCG
GGCCTGGTCGACAAGGGCAACTCGGTGATCGTCATCGAGCACAACCTGGACGTCATCAAGACGGCGGACTGGGTGATCGA
CATGGGTCCCGAGGGCGGCAACGGCGGTGGCCTCGTCATCGCGGAGGGCACGCCCGAGGAGGTCGCCTCCGAGCCGGCCA
GCCACACCGGAAAGTTCCTGCGGGACATTCTGGGGGCGGACCGGATCAGTGACGCGGCGTCCTCGCCGGGGCGGAAGTCC
GCGAAGCGGGCTGCCCCGGCCAAGAAGGCGGCGTCCGCGGCCAAGGCCGCGCCGGCCGCCCGGAAGGCGGCCTCGGCGGC
CGCCACGAAGAAGGCCGCCCCGGCGAAGAAGGCGACCCGGGCCCGCAAGGCCTGA

Domains

Predicted by InterProScan.

UvrA interaction domain (UvrA_inter)

(131-238)

UvrA DNA-binding domain (UvrA_DNA-bind)

(294-403)

ABC transporter (ABC_tran)

(628-864)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

56.931

94.124

0.536
  uvrA Streptococcus pneumoniae TIGR4

56.931

94.124

0.536
  uvrA Streptococcus pneumoniae D39

56.931

94.124

0.536