Detailed information NTG0473853

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: LLUL021_RS12360
• Genome accession: NZ_CP070263
• Coordinates: 2417229..2419751 (-)
• Length: 840 a.a.
• NCBI ID: WP_003131999.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain UL021
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2412229..2424751

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLUL021_RS12340 (LLUL021_12295)	ruvB	2412486..2413487 (-)	1002	WP_003131994.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
LLUL021_RS12345 (LLUL021_12300)	ruvA	2413614..2414207 (-)	594	WP_003131995.1	Holliday junction branch migration protein RuvA	Machinery gene
LLUL021_RS12350 (LLUL021_12305)	hexB	2414320..2416290 (-)	1971	WP_014570854.1	DNA mismatch repair endonuclease MutL	Machinery gene
LLUL021_RS12355 (LLUL021_12310)	-	2416419..2417114 (-)	696	WP_003131997.1	hypothetical protein	-
LLUL021_RS12360 (LLUL021_12315)	hexA	2417229..2419751 (-)	2523	WP_003131999.1	DNA mismatch repair protein MutS	Machinery gene
LLUL021_RS12365 (LLUL021_12320)	-	2419945..2420292 (-)	348	WP_012898702.1	RicAFT regulatory complex protein RicA family protein	-
LLUL021_RS12370 (LLUL021_12325)	-	2420508..2421389 (-)	882	WP_003132001.1	NAD(P)-dependent oxidoreductase	-
LLUL021_RS12375 (LLUL021_12330)	-	2421431..2421637 (-)	207	WP_003132002.1	hypothetical protein	-
LLUL021_RS12385 (LLUL021_12340)	-	2421932..2422309 (-)	378	WP_003132003.1	DUF1634 domain-containing protein	-
LLUL021_RS12390 (LLUL021_12345)	-	2422309..2423160 (-)	852	WP_010906392.1	sulfite exporter TauE/SafE family protein	-
LLUL021_RS12395 (LLUL021_12350)	-	2423346..2423525 (+)	180	WP_003132007.1	hypothetical protein	-

Sequence

Protein

• Length: 840 a.a.
• Molecular weight: 94279.25 Da
• Isoelectric Point: 4.6787

>NTDB_id=473853 LLUL021_RS12360 WP_003131999.1 2417229..2419751(-) (hexA) [Lactococcus lactis subsp. lactis strain UL021]
MAERISPGMQQYLDIKQDYPDAFLLFRMGDFYELFYDDAVNAAQILELTLTSRNKNSENPIPMAGVPHHAAAEYIDKLVD
LGYKVAVAEQMEDPKKAVGIVKRAVTQVITPGTTIDTANSVDNNFLVAIDFKDKHYALSYMDLSTGEFKVTELSEFSAVV
GEIASLKAREIVAGFTLDESQLKVFERQMNLLISEQIEIPENLLIDLSGLTALENQVASKLLAYVKETQMRDLSHLQEVE
HYEIKDFLQMDFATKSSLELTANKRENKKHGTLYWLLDETKTAMGTRMLRSWIDRPLVSNSAIQKRMEIVQIFLDHFFER
SDLIEALKGVYDLERLASRVSFGKAVPVDFLQLANSLSNVPAIKNILGMLNEAPLEELKSQLDEIPELSGLINSAISENA
SRTITEGGIIKKGYNAQLDKYREALENGTSWIAKLEADEKAKTGISTLRIDYNRKDGYYFHITQSQLNSVPEHFYRKATL
KNSERFGSQELTEIEEIMLEAREKSSSLEYDLFMDLRTETEQYIGRLQALAKTIAEIDCLQSLSVVAEKQGYIRPTLTDG
SRIVEIKGGRHAVVEAVMGAQEYVPNDIELPEQTDIQLITGPNMSGKSTYMRQFALTVIMAQIGSFVPAETANLPIFDAI
FTRIGASDNLISGESTFMVEMSEANHAIQKASSRSLIIFDELGRGTATYDGMALAQAIIEYVHDHIGAKTLFATHYHELT
DLDEALVHLDNVHVATLEQNGNVTFLHKITEGPADKSYGIHVAKIAGLPQPLLERADLILQKLENKPLPAKKVADEQEQL
SLFDFTENSSEIIEKIKRQNVDNMTAREALNFLWELKDSL

Nucleotide

• Length: 2523 bp

>NTDB_id=473853 LLUL021_RS12360 WP_003131999.1 2417229..2419751(-) (hexA) [Lactococcus lactis subsp. lactis strain UL021]
ATGGCTGAAAGAATTTCACCAGGAATGCAACAATATTTAGACATCAAACAAGATTATCCCGATGCTTTCTTGCTCTTTCG
GATGGGCGATTTTTATGAGCTTTTCTATGATGATGCAGTGAATGCTGCCCAAATATTAGAATTAACCCTGACTTCAAGAA
ATAAAAATTCAGAAAATCCAATTCCAATGGCTGGTGTTCCCCACCATGCAGCAGCTGAATACATTGATAAATTGGTTGAT
TTAGGCTACAAAGTGGCTGTTGCTGAACAAATGGAAGACCCGAAAAAAGCGGTCGGAATTGTTAAACGGGCAGTAACACA
GGTGATTACCCCAGGGACAACGATTGACACTGCAAATTCGGTTGATAATAATTTCTTGGTGGCAATTGACTTCAAAGATA
AACATTATGCTCTTTCCTATATGGACTTATCAACTGGGGAATTCAAGGTGACAGAGCTCAGCGAATTTTCAGCGGTGGTG
GGAGAAATTGCTTCACTCAAGGCGCGAGAAATTGTAGCTGGTTTTACTTTAGATGAAAGTCAGTTAAAAGTTTTTGAAAG
ACAAATGAATCTTTTGATTTCAGAACAAATTGAAATTCCGGAAAATTTACTGATAGATTTGTCAGGATTGACCGCCCTAG
AAAATCAAGTCGCTTCAAAATTGTTGGCTTATGTTAAAGAAACACAAATGCGTGATTTGAGTCACTTACAAGAAGTTGAA
CATTATGAAATTAAAGACTTTTTGCAAATGGACTTTGCGACAAAATCATCTTTAGAGCTGACGGCAAATAAAAGAGAAAA
TAAAAAACATGGCACACTTTATTGGTTGCTTGATGAGACGAAAACAGCGATGGGAACCAGAATGTTACGGTCGTGGATTG
ACCGCCCTTTGGTTTCAAATTCAGCCATTCAAAAACGAATGGAAATTGTTCAAATTTTCTTAGACCATTTCTTTGAGCGT
TCCGATTTGATAGAAGCCTTAAAAGGGGTCTATGATTTAGAACGTTTGGCTTCACGTGTTTCTTTTGGTAAGGCTGTTCC
GGTTGATTTTTTGCAGCTGGCTAATTCTTTATCAAATGTCCCTGCTATCAAAAATATTTTGGGAATGCTTAATGAAGCTC
CATTAGAAGAGTTAAAAAGCCAATTAGACGAAATTCCAGAATTATCTGGTTTAATTAATTCAGCTATTAGTGAGAATGCC
TCAAGAACGATTACTGAAGGGGGCATTATTAAAAAAGGCTACAATGCTCAATTAGATAAATATCGGGAGGCGCTTGAAAA
TGGGACTTCTTGGATTGCTAAATTGGAAGCAGATGAAAAAGCCAAGACAGGAATTTCCACACTGCGAATTGATTATAATC
GTAAGGATGGTTATTATTTTCATATTACTCAAAGTCAGCTGAATAGTGTTCCTGAACATTTTTATCGTAAGGCAACTTTG
AAAAATTCTGAGCGTTTTGGTTCTCAGGAATTAACTGAAATTGAAGAAATTATGTTGGAAGCGCGTGAAAAATCATCATC
TCTAGAATATGATTTATTCATGGACCTTCGGACTGAAACGGAGCAATATATTGGCAGACTACAAGCTCTAGCCAAAACAA
TTGCTGAAATTGATTGTTTACAAAGTCTATCTGTCGTTGCCGAAAAACAAGGATATATCCGTCCGACGCTTACAGACGGT
TCAAGAATTGTTGAAATTAAAGGCGGTCGTCATGCGGTCGTTGAAGCGGTCATGGGTGCTCAAGAATATGTGCCAAATGA
TATTGAACTGCCTGAACAAACAGATATTCAACTCATCACAGGACCGAATATGTCAGGTAAATCAACCTACATGCGTCAAT
TTGCTTTGACGGTGATTATGGCTCAAATTGGATCTTTTGTTCCAGCCGAAACAGCCAATTTACCAATTTTTGATGCCATC
TTTACACGGATTGGTGCCAGTGATAACTTGATTTCAGGGGAATCGACCTTTATGGTTGAAATGTCTGAGGCCAATCATGC
CATTCAAAAGGCAAGCAGTCGCAGCCTGATTATTTTTGATGAATTAGGGCGAGGAACGGCAACTTATGATGGGATGGCTC
TAGCTCAAGCAATTATTGAATATGTTCATGACCATATTGGGGCAAAAACCTTGTTTGCTACGCATTATCATGAATTGACA
GACTTAGATGAAGCGCTCGTTCATCTTGATAATGTCCATGTTGCTACTTTGGAACAAAATGGGAATGTGACTTTTTTGCA
TAAAATAACAGAGGGACCAGCTGATAAATCCTATGGGATTCATGTGGCGAAAATTGCAGGTTTACCACAGCCTTTGTTAG
AGCGAGCAGATTTGATTTTGCAGAAGTTAGAAAATAAACCTTTGCCTGCTAAAAAAGTTGCTGATGAACAAGAACAACTT
AGTTTATTTGATTTTACCGAAAATTCTTCAGAAATTATTGAAAAGATAAAAAGGCAAAATGTTGATAATATGACTGCAAG
AGAGGCATTGAATTTCTTGTGGGAACTTAAAGATTCACTTTGA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (7-116)

• MutS family domain IV (MutS_IV) (413-503)

• MutS domain II (MutS_II) (124-237)

• MutS domain III (MutS_III) (254-544)

• MutS domain V (MutS_V) (598-784)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	64.336	100	0.646
mutS	Pseudomonas stutzeri strain ATCC 17587	37.806	100	0.386