Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   H5405_RS13420 Genome accession   NZ_CP060085
Coordinates   2780108..2780764 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain HAB-2     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2775108..2785764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H5405_RS13400 (H5405_13400) spxH 2775347..2776249 (+) 903 WP_003155024.1 protease adaptor protein SpxH -
  H5405_RS13405 (H5405_13405) - 2776535..2776702 (+) 168 WP_003155026.1 hypothetical protein -
  H5405_RS13410 (H5405_13410) pepF 2776740..2778569 (-) 1830 WP_139325667.1 oligoendopeptidase F Regulator
  H5405_RS13415 (H5405_13415) - 2778797..2779957 (-) 1161 WP_007610612.1 competence protein CoiA family protein -
  H5405_RS13420 (H5405_13420) mecA 2780108..2780764 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  H5405_RS13425 (H5405_13425) - 2780747..2780857 (-) 111 Protein_2670 adaptor protein MecA -
  H5405_RS13430 (H5405_13430) - 2781040..2781696 (+) 657 WP_007610610.1 TerC family protein -
  H5405_RS13435 (H5405_13435) spx 2781753..2782148 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  H5405_RS13440 (H5405_13440) - 2782327..2782905 (-) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  H5405_RS13445 (H5405_13445) - 2783023..2784210 (-) 1188 WP_029325948.1 putative glycoside hydrolase -
  H5405_RS13450 (H5405_13450) oppF 2784317..2785234 (-) 918 WP_007610608.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=473813 H5405_RS13420 WP_003155032.1 2780108..2780764(-) (mecA) [Bacillus velezensis strain HAB-2]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=473813 H5405_RS13420 WP_003155032.1 2780108..2780764(-) (mecA) [Bacillus velezensis strain HAB-2]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATTAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895