Detailed information    

insolico Bioinformatically predicted

Overview

Name   comH   Type   Machinery gene
Locus tag   KHP_RS07340 Genome accession   NC_017382
Coordinates   1504921..1506354 (-) Length   477 a.a.
NCBI ID   WP_000751688.1    Uniprot ID   A0AAI7ZX54
Organism   Helicobacter pylori 51     
Function   import of DNA into the periplasm (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1485080..1511358 1504921..1506354 within 0


Gene organization within MGE regions


Location: 1485080..1511358
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KHP_RS07250 - 1485080..1485517 (-) 438 WP_000248397.1 Panacea domain-containing protein -
  KHP_RS08275 - 1485741..1487369 (-) 1629 Protein_1403 RNA-directed DNA polymerase -
  KHP_RS07270 (KHP_1367) - 1487380..1487901 (-) 522 WP_000413030.1 hypothetical protein -
  KHP_RS08570 (KHP_1368) - 1487902..1490274 (-) 2373 Protein_1405 Eco57I restriction-modification methylase domain-containing protein -
  KHP_RS08575 - 1490337..1491774 (-) 1438 Protein_1406 class I SAM-dependent DNA methyltransferase -
  KHP_RS07280 - 1491901..1494055 (-) 2155 Protein_1407 hypothetical protein -
  KHP_RS07285 - 1494118..1494975 (-) 858 Protein_1408 hypothetical protein -
  KHP_RS07290 (KHP_1371) - 1495066..1495719 (+) 654 WP_001042543.1 IS607-like element IS607 family transposase -
  KHP_RS07295 (KHP_1372) - 1495694..1496951 (+) 1258 Protein_1410 RNA-guided endonuclease InsQ/TnpB family protein -
  KHP_RS07300 (KHP_1373) - 1496998..1499055 (-) 2058 Protein_1411 DEAD/DEAH box helicase family protein -
  KHP_RS07305 - 1499058..1499639 (-) 582 WP_228839929.1 site-specific DNA-methyltransferase -
  KHP_RS07310 (KHP_1374) - 1499644..1501017 (-) 1374 WP_014537410.1 site-specific DNA-methyltransferase -
  KHP_RS07315 (KHP_1375) recG 1501056..1502921 (-) 1866 WP_001158394.1 ATP-dependent DNA helicase RecG -
  KHP_RS07320 (KHP_1376) - 1503003..1503356 (+) 354 WP_000837003.1 hypothetical protein -
  KHP_RS07325 (KHP_1377) - 1503360..1503995 (+) 636 WP_000668030.1 outer membrane protein -
  KHP_RS07330 (KHP_1378) - 1503992..1504744 (-) 753 WP_000767536.1 exodeoxyribonuclease III -
  KHP_RS07340 (KHP_1379) comH 1504921..1506354 (-) 1434 WP_000751688.1 hypothetical protein Machinery gene
  KHP_RS07350 (KHP_1380) dnaA 1506576..1507943 (-) 1368 WP_000380587.1 chromosomal replication initiator protein DnaA -
  KHP_RS07355 (KHP_1381) - 1508095..1508631 (+) 537 WP_014537411.1 purine-nucleoside phosphorylase -
  KHP_RS07360 (KHP_1382) - 1508678..1508917 (+) 240 WP_000461845.1 DUF2443 domain-containing protein -
  KHP_RS07365 (KHP_1383) glmS 1508918..1510711 (+) 1794 WP_000334405.1 glutamine--fructose-6-phosphate transaminase (isomerizing) -
  KHP_RS07370 (KHP_1384) thyX 1510732..1511358 (+) 627 WP_000451936.1 FAD-dependent thymidylate synthase -

Sequence

Protein


Download         Length: 477 a.a.        Molecular weight: 54740.72 Da        Isoelectric Point: 7.2025

>NTDB_id=47118 KHP_RS07340 WP_000751688.1 1504921..1506354(-) (comH) [Helicobacter pylori 51]
MKKTLCLSFFLTFSNPLQALVIELLEEVKTSPHKGTFKAKVLDSKEPRQVLGVYNISPHKKLTLTITHISTAIVYQPLDE
KLSLEMILNPNRPTIPRNTQIVFSSKELKEPHQMPSLNAPIQKPQNKPTSSQQSLQNFPYTESKLGSKNPKNSLLQPLAT
PNKISSANEVKTPTNDTKPPLKHSSEDQENNLFVAPPTEKTLPNNTPNANINEHNESNENRDSVEKQAIRDPNVKEFACG
KWVYDDENLQAYRPSILKRVDEDKQTATDITPCDYSNAENKSGKITTPYTKISVHKTEPLEEPQTFEAKNNFTILQARSS
TEKCKRARARKDGTTRQCYLIEEPLKQAWESEYEITTQLVKATYERPKQDDQTEPTFYETSELAYSSTRKSEITHNELNL
NEKFMEFVEVYERHYLNDIVKESSEYKEWVKNHVRFKEGVCMVLEIEEQPRAKSTPLSIENSRVVCVKKGNYLFNEV

Nucleotide


Download         Length: 1434 bp        

>NTDB_id=47118 KHP_RS07340 WP_000751688.1 1504921..1506354(-) (comH) [Helicobacter pylori 51]
ATGAAAAAAACCCTTTGTCTGTCTTTCTTTCTGACTTTCTCTAACCCTCTTCAAGCCCTTGTGATCGAGCTTTTAGAAGA
AGTCAAAACTTCGCCGCATAAAGGCACTTTTAAGGCTAAAGTCCTTGATTCTAAAGAACCAAGACAAGTTTTAGGCGTTT
ATAATATCTCCCCACACAAAAAACTCACGCTCACTATCACCCACATATCCACTGCAATTGTCTATCAACCCCTTGATGAA
AAACTTTCTTTAGAAATGATCTTAAACCCTAACCGCCCTACTATTCCTAGAAACACCCAAATTGTTTTTTCTTCAAAAGA
ATTGAAAGAGCCACACCAAATGCCTTCTTTAAACGCGCCCATACAAAAACCACAAAACAAACCCACTTCATCGCAACAAT
CTCTTCAAAACTTTCCTTACACAGAGTCCAAACTAGGCTCTAAAAACCCTAAAAACAGCCTTTTACAGCCTTTAGCCACT
CCTAATAAAATAAGCTCCGCTAATGAAGTTAAAACACCAACAAACGACACTAAACCCCCTTTAAAGCATTCTTCAGAAGA
TCAAGAAAACAACCTCTTTGTAGCACCACCCACTGAAAAAACGCTCCCTAACAACACCCCTAACGCTAATATTAATGAAC
ACAATGAAAGCAATGAAAATAGGGATAGTGTGGAAAAACAAGCGATTAGAGATCCTAATGTTAAAGAATTTGCGTGCGGG
AAGTGGGTCTATGATGATGAAAATCTACAAGCCTATCGCCCAAGCATTTTAAAACGCGTTGATGAAGACAAACAGACTGC
GACAGACATTACCCCTTGCGACTACAGCAACGCTGAAAATAAAAGCGGTAAAATCACTACCCCCTATACTAAAATCTCTG
TTCATAAAACAGAGCCTTTAGAAGAGCCGCAAACTTTTGAAGCTAAAAACAATTTTACCATCCTCCAAGCCAGAAGCTCT
ACAGAAAAATGCAAAAGAGCCAGAGCGCGAAAAGACGGCACGACTAGGCAATGCTATCTCATAGAAGAGCCTTTAAAACA
AGCGTGGGAGAGTGAGTATGAAATCACCACGCAATTAGTGAAAGCCACTTATGAGCGCCCCAAACAAGACGATCAAACAG
AGCCGACTTTCTATGAAACTAGCGAATTGGCTTATTCTTCCACACGAAAAAGCGAAATAACGCATAATGAATTGAATTTG
AATGAAAAGTTCATGGAATTTGTGGAAGTGTATGAGAGGCATTATTTAAACGATATAGTCAAAGAAAGCAGTGAATACAA
AGAATGGGTTAAAAACCATGTGCGCTTTAAAGAAGGGGTGTGCATGGTTTTAGAAATAGAAGAGCAACCACGAGCCAAAA
GCACGCCTTTGAGTATTGAAAACTCTCGTGTTGTTTGTGTCAAAAAGGGGAATTATTTATTCAACGAAGTTTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comH Helicobacter pylori 26695

91.649

100

0.92

Multiple sequence alignment