Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HP2018_RS03925 Genome accession   NC_017381
Coordinates   815550..817334 (+) Length   594 a.a.
NCBI ID   WP_000774420.1    Uniprot ID   -
Organism   Helicobacter pylori 2018     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 810550..822334
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HP2018_RS03895 (hp2018_0798) motB 811314..812087 (+) 774 WP_001085350.1 flagellar motor protein MotB -
  HP2018_RS03900 (hp2018_0799) - 812093..812530 (+) 438 WP_041202439.1 hypothetical protein -
  HP2018_RS03905 (hp2018_0801) - 812599..814260 (+) 1662 WP_001133311.1 ABC transporter permease/substrate-binding protein -
  HP2018_RS03910 (hp2018_0802) - 814263..814913 (+) 651 WP_000659401.1 ATP-binding cassette domain-containing protein -
  HP2018_RS03915 (hp2018_0803) - 814917..815096 (-) 180 WP_001876614.1 hypothetical protein -
  HP2018_RS03920 (hp2018_0804) - 815088..815549 (+) 462 WP_000437174.1 hypothetical protein -
  HP2018_RS03925 (hp2018_0805) uvrC 815550..817334 (+) 1785 WP_000774420.1 excinuclease ABC subunit UvrC Machinery gene
  HP2018_RS03930 (hp2018_0806) - 817344..818609 (+) 1266 WP_000746739.1 homoserine dehydrogenase -
  HP2018_RS03935 (hp2018_0807) - 818610..818954 (+) 345 WP_001211718.1 YraN family protein -
  HP2018_RS03940 (hp2018_0808) trxA 819046..819366 (+) 321 WP_000020188.1 thioredoxin -
  HP2018_RS03945 (hp2018_0809) trxB 819372..820307 (+) 936 WP_000564458.1 thioredoxin-disulfide reductase -
  HP2018_RS03950 (hp2018_0810) - 820679..821500 (+) 822 WP_001263362.1 glycosyltransferase family 25 protein -
  HP2018_RS03955 (hp2018_0811) - 821718..821966 (-) 249 WP_000790555.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68690.80 Da        Isoelectric Point: 9.6763

>NTDB_id=47092 HP2018_RS03925 WP_000774420.1 815550..817334(+) (uvrC) [Helicobacter pylori 2018]
MADLLSSLKNLSSSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNPRASLRVQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNETLKELQEFISHQYSKKIVLNIPKKGDKLALIEIAMKNAQEIFSQEKTSSEDRILEEARSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENNVFQKDSYRRYHLKGSNEYDQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDVIHTISNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLRKRN

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=47092 HP2018_RS03925 WP_000774420.1 815550..817334(+) (uvrC) [Helicobacter pylori 2018]
ATGGCTGATTTATTATCCAGTTTGAAAAACCTTTCTAGTAGTAGTGGCGTTTATCAATATTTTGATAAAAACCGCCAATT
ACTCTACATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCGTAATAATGAAATCACGCCCA
ATCCTCGCGCAAGCTTACGAGTCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTGATCAAGCAGCTCAAGCCTAAATACAACATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGACTTCCCCATCCCTTTAATCACACGAAAAATCTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTCACGAGTGGGGCTAAGGACATTTTGGACAGCTTGTATGAATTGCTCCCTTTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACTAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTATAGGGATAGGATTGCTAAAATCCAAAAAATC
GCCCCCTTCACTTGCATGGATTTAGCCAAACTCTACGATCTGGATATTTTTGCTTTTTATGGTGGGAACAATAAAGCGGT
GTTAGTGAAAATGTTCATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAGC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATATTCTAAAAAAATCGTTCTTAATATCCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
GTGAAGATCGGATTTTAGAAGAAGCGCGATCGCTCTTCAATTTAGAGTGCGTGCCTTATAGGGTAGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGTATTTCAAAAAGACTCTTATCGGCG
TTACCATTTAAAAGGCTCTAACGAATACGATCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCTAAAGAAC
CACCGCCTAATTTGTGGGTGATAGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGCTCTAAAGGGGGCGCTAAAGACGTTAT
CCATACGATTAGTAATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAGAAAACGAAATTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

95.784

99.832

0.956

Multiple sequence alignment