Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   H3L95_RS10935 Genome accession   NZ_CP059566
Coordinates   2289303..2290745 (-) Length   480 a.a.
NCBI ID   WP_003755930.1    Uniprot ID   C6M1T5
Organism   Neisseria sicca strain DSM 17713     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2284303..2295745
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H3L95_RS10910 (H3L95_10910) bioH 2285374..2286120 (-) 747 WP_003755919.1 pimeloyl-ACP methyl ester esterase BioH -
  H3L95_RS10915 (H3L95_10915) - 2286134..2286871 (+) 738 WP_070493550.1 ComF family protein -
  H3L95_RS10920 (H3L95_10920) trmL 2286936..2287400 (+) 465 WP_003755921.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
  H3L95_RS10925 (H3L95_10925) - 2287549..2288274 (+) 726 WP_003741901.1 septal ring lytic transglycosylase RlpA family protein -
  H3L95_RS10930 (H3L95_10930) - 2288510..2288842 (+) 333 WP_003741903.1 zinc ribbon domain-containing protein YjdM -
  H3L95_RS10935 (H3L95_10935) pilA 2289303..2290745 (-) 1443 WP_003755930.1 signal recognition particle-docking protein FtsY Machinery gene
  H3L95_RS10940 (H3L95_10940) - 2290976..2291422 (+) 447 WP_003755932.1 hypothetical protein -
  H3L95_RS10945 (H3L95_10945) - 2291449..2291649 (+) 201 WP_164907879.1 hypothetical protein -
  H3L95_RS10955 (H3L95_10955) - 2292188..2292475 (-) 288 WP_003755935.1 DUF924 family protein -
  H3L95_RS10960 (H3L95_10960) - 2292478..2293227 (-) 750 WP_003755938.1 SDR family oxidoreductase -
  H3L95_RS10965 (H3L95_10965) - 2293294..2293653 (-) 360 WP_164907876.1 hypothetical protein -
  H3L95_RS10970 (H3L95_10970) - 2293819..2295198 (-) 1380 WP_003755944.1 hypothetical protein -
  H3L95_RS10975 (H3L95_10975) - 2295289..2295618 (-) 330 WP_040667937.1 hypothetical protein -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 51584.97 Da        Isoelectric Point: 4.3993

>NTDB_id=470747 H3L95_RS10935 WP_003755930.1 2289303..2290745(-) (pilA) [Neisseria sicca strain DSM 17713]
MFSFFRRKKKQETPAQEETRIQETAAEAVENAEAAVSQTLETVQENIGEKAEELTAAVETAVESAKERTEEICETVVEHV
SETVEHVREAVGETSSETVEKVEERVEAVSETVAENVSAAVEHVHEAVSEGSSETAEAVETQAEAAPTTSEEHSVPAFEN
TAVATSSETSEPSETEPKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELETVLITSDMGMEATEYLMKDVRN
RVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPDTKEPFVIMLAGINGAGKTTSIGKLAKYFQAQGKSVLLAAGDTFR
AAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHLMEEIKKVKRVLQKAMPDAPHE
IIVVLDANIGQNAVNQVKAFDEALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGVGEGIDDLRPFDARAFVDALLD

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=470747 H3L95_RS10935 WP_003755930.1 2289303..2290745(-) (pilA) [Neisseria sicca strain DSM 17713]
ATGTTCAGCTTCTTCCGCCGCAAGAAAAAACAGGAAACGCCAGCTCAAGAAGAAACCCGCATTCAGGAAACCGCCGCCGA
AGCCGTAGAGAACGCTGAAGCTGCCGTTTCGCAAACGCTTGAAACGGTTCAGGAAAACATCGGCGAAAAAGCGGAAGAGC
TGACGGCGGCAGTTGAAACGGCGGTAGAAAGTGCCAAAGAGCGCACCGAAGAAATCTGCGAGACTGTGGTTGAACATGTT
TCCGAAACGGTCGAACACGTCCGCGAGGCAGTCGGCGAAACGTCGTCTGAAACGGTCGAAAAAGTGGAAGAACGCGTGGA
AGCGGTCAGCGAAACCGTTGCCGAAAATGTTTCCGCAGCGGTAGAACACGTCCATGAAGCGGTCAGCGAAGGGTCGTCTG
AAACCGCAGAAGCCGTCGAAACCCAAGCTGAAGCCGCGCCGACAACATCCGAAGAACATTCCGTACCGGCCTTTGAAAAT
ACAGCCGTCGCAACGTCGTCTGAAACCTCTGAACCGTCCGAAACCGAACCCAAACTCGGCTGGGCGGCGCGTTTGAAACA
GGGTTTGACCAAATCGCGCGACAAAATGGCGAAATCGCTGGCGGGCGTGTTCGGCGGCGGGCAAATCGACGAAGACTTGT
ACGAAGAGCTGGAAACCGTGCTGATTACCAGCGACATGGGCATGGAAGCGACGGAATATCTGATGAAAGACGTGCGCAAC
CGCGTCAGCCTCAAGGGGCTGAAAGACGGCAACGAGTTGCGCGGCGCATTGAAAGAAGCTTTGTACGACTTGATTAAGCC
GTTGGAAAAACCGCTGGTCTTGCCCGACACGAAAGAGCCGTTCGTCATCATGTTGGCGGGCATCAACGGCGCGGGTAAAA
CCACTTCCATCGGCAAACTCGCCAAATATTTCCAAGCTCAGGGCAAATCCGTGCTGCTTGCCGCAGGCGACACCTTCCGC
GCCGCCGCCCGCGAGCAGCTTCAGGCATGGGGCGAACGCAACAACGTTACCGTCATTTCGCAAACCACAGGCGATTCCGC
CGCCGTCTGCTTCGATGCCGTCCAAGCCGCCAAAGCGCGCGGCATCGACATCGTGCTTGCCGACACCGCCGGCCGCCTGC
CCACGCAGCTTCATTTGATGGAAGAAATCAAAAAAGTGAAGCGCGTGCTGCAAAAAGCAATGCCCGACGCGCCGCACGAA
ATCATCGTCGTCCTCGATGCCAACATCGGGCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGAAGCGTTAGGACTGAC
CGGTCTGATTGTGACCAAACTCGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTTGCCTCCGACCGCCCCGTCCCCG
TCCGCTACATTGGCGTGGGCGAAGGCATAGACGATTTGCGCCCGTTTGACGCGCGCGCTTTTGTGGACGCGTTGTTGGAC
TAA

Domains

Predicted by InterproScan.

SRP54-type protein, helical bundle domain (SRP54_N)

(195-261)

SRP54-type protein, GTPase domain (SRP54)

(280-479)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C6M1T5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

74.792

100

0.748