Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   H3L95_RS02380 Genome accession   NZ_CP059566
Coordinates   478650..480875 (-) Length   741 a.a.
NCBI ID   WP_040667839.1    Uniprot ID   -
Organism   Neisseria sicca strain DSM 17713     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 473650..485875
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H3L95_RS02355 (H3L95_02355) xerD 474066..474941 (+) 876 WP_003755327.1 site-specific tyrosine recombinase XerD -
  H3L95_RS02360 (H3L95_02360) clpA 475011..477296 (-) 2286 WP_003755325.1 ATP-dependent Clp protease ATP-binding subunit ClpA -
  H3L95_RS02365 (H3L95_02365) clpS 477298..477609 (-) 312 WP_003755322.1 ATP-dependent Clp protease adapter ClpS -
  H3L95_RS02370 (H3L95_02370) - 477922..478125 (+) 204 WP_002217533.1 cold-shock protein -
  H3L95_RS02375 (H3L95_02375) - 478208..478435 (+) 228 WP_003763006.1 hypothetical protein -
  H3L95_RS02380 (H3L95_02380) comA 478650..480875 (-) 2226 WP_040667839.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  H3L95_RS02385 (H3L95_02385) - 481034..481942 (-) 909 WP_003755313.1 Dyp-type peroxidase -
  H3L95_RS02390 (H3L95_02390) - 482075..483160 (+) 1086 WP_003755310.1 metallophosphoesterase -
  H3L95_RS02395 (H3L95_02395) - 483603..483803 (+) 201 WP_003755307.1 (2Fe-2S)-binding protein -
  H3L95_RS02400 (H3L95_02400) - 483928..484182 (+) 255 WP_003755305.1 glutaredoxin family protein -
  H3L95_RS02405 (H3L95_02405) - 484291..484725 (-) 435 WP_003755302.1 hypothetical protein -

Sequence

Protein


Download         Length: 741 a.a.        Molecular weight: 80004.75 Da        Isoelectric Point: 9.5480

>NTDB_id=470722 H3L95_RS02380 WP_040667839.1 478650..480875(-) (comA) [Neisseria sicca strain DSM 17713]
MLKYYGLPFWAVGVIASFALPSVPHWAAWLAAALVLLAASRRFAVAGMMLCVLLGAAYGVFRTEAALSAQWPLNGASESV
LTVEVADMPRGDGRRVQFAAKAWTEDGRQFDLLLSDYQKRDWAVGSRWKVSARLKPVIGEVNLRGLNREAWALANGLDGA
GTLGKGRSLVREGGGVGLAVWRDAVSRRWQAVEADSPDFSDGIGLMRALSIGEQSALRPELWQAFRPLGLTHLVSISGLH
VTMVAVLAGWLVKLIFRRLSWIPAKPRVWILAGGAAGALFYALLAGFSVPTQRSVLMLAAFAWAWWRGSLSSGWTAWWQA
LAVVVLIDPLAVLGVGTWLSFGLVAALIWASAGRLKERGWRLAVRGQWAATVLSVVLLGYIFASLPIISPLVNAAMIPWF
SWVLTPLALLGSVLPFAPLQWAAAGLAEYTLRGLVWLAEVSPEFAVAAAPVPLLVLAFAAALLWLLPRGLGLRPWACLVL
AGFVFYRPDRLDDGLARITVMDAGQGLSVLVQTRSRNLLFDTGTVQAAQTGIVPSLNAMGVRRLDTLILSHHDSDHDGGL
DAVSDIEIGETLAGQPEFYPNAKFCAEAQWQWDGVNFELLRSSENPVGEDNDRSCVLRVVSDGQALLVTGDLGVKGEAGL
VERYGSSLYSQILILGHHGSNTASSGGFLNTVAPKYAVASSGYANAYKHPTPAVQTRVRAHGATLLRTDLSGALVFELGG
DEVFKGRLKKDKFYWQKKPFE

Nucleotide


Download         Length: 2226 bp        

>NTDB_id=470722 H3L95_RS02380 WP_040667839.1 478650..480875(-) (comA) [Neisseria sicca strain DSM 17713]
TTGCTGAAATATTATGGATTGCCGTTTTGGGCAGTCGGCGTCATTGCCTCGTTCGCTTTGCCGTCCGTACCGCATTGGGC
TGCGTGGCTGGCGGCGGCATTGGTTTTGCTGGCGGCTTCACGGCGGTTTGCGGTGGCGGGAATGATGCTGTGCGTCCTGC
TCGGCGCGGCTTACGGCGTGTTTCGGACGGAAGCGGCTTTGTCGGCGCAATGGCCGCTGAACGGGGCTTCGGAGTCGGTG
TTGACGGTTGAAGTCGCGGATATGCCGCGCGGCGACGGGCGGCGGGTGCAGTTTGCGGCGAAGGCGTGGACGGAGGACGG
GCGGCAGTTTGATTTATTGCTGTCGGATTATCAGAAACGCGATTGGGCGGTAGGCAGCCGCTGGAAGGTGTCGGCACGGC
TCAAGCCGGTTATCGGCGAAGTGAACCTGCGCGGGTTGAACCGCGAGGCTTGGGCGTTGGCAAACGGTTTGGATGGTGCG
GGTACCCTGGGCAAAGGCAGGAGCTTGGTTCGCGAGGGCGGCGGTGTCGGCTTGGCGGTGTGGCGCGATGCGGTCAGCCG
CCGTTGGCAGGCTGTCGAGGCGGACAGCCCGGATTTTTCGGACGGTATCGGTCTGATGCGGGCTTTGAGCATAGGCGAAC
AATCGGCGTTGAGGCCCGAACTGTGGCAGGCGTTCCGACCTTTGGGCTTGACGCACTTGGTCAGCATTTCGGGGCTGCAC
GTTACGATGGTGGCGGTGTTGGCGGGTTGGCTGGTCAAACTAATTTTCAGACGACTGTCTTGGATACCGGCAAAACCGCG
CGTGTGGATTTTGGCGGGCGGCGCGGCAGGGGCTTTGTTTTATGCGCTGCTGGCGGGTTTTTCCGTGCCGACGCAGCGCA
GTGTTTTGATGTTGGCGGCGTTTGCCTGGGCTTGGTGGCGCGGCAGTCTGTCTTCGGGCTGGACGGCATGGTGGCAGGCT
TTGGCGGTGGTGGTGTTGATTGATCCATTGGCGGTTTTGGGTGTTGGCACTTGGCTATCGTTCGGCTTGGTTGCCGCCTT
GATTTGGGCTTCGGCAGGTCGTCTGAAAGAACGCGGCTGGCGTTTGGCTGTACGCGGACAATGGGCGGCGACGGTTTTGT
CAGTGGTACTGCTGGGCTATATTTTTGCGTCGTTGCCCATCATCAGCCCTTTGGTCAATGCGGCGATGATTCCTTGGTTT
TCTTGGGTATTGACGCCTTTGGCGCTGCTGGGGTCGGTGTTGCCGTTCGCACCTTTGCAATGGGCGGCGGCAGGTTTGGC
AGAATACACTTTGCGCGGCTTGGTTTGGCTGGCGGAGGTGTCGCCCGAATTTGCCGTAGCCGCCGCGCCTGTGCCGCTGT
TGGTTTTGGCTTTTGCGGCGGCTTTGCTGTGGCTGTTGCCGCGCGGACTGGGTCTGCGGCCTTGGGCGTGTTTGGTGTTG
GCTGGATTTGTGTTTTACCGCCCCGACCGTTTGGACGACGGGTTGGCGCGAATTACCGTGATGGATGCGGGACAGGGTTT
GTCGGTGTTGGTACAAACGCGCAGCCGCAACCTGCTGTTTGACACGGGTACGGTGCAGGCGGCGCAAACAGGTATCGTGC
CAAGCCTGAACGCCATGGGCGTGCGCCGTTTGGACACGCTGATTCTGTCGCATCACGACAGCGACCACGACGGCGGGTTG
GACGCCGTTTCCGATATTGAAATCGGCGAAACGCTGGCGGGACAGCCTGAGTTTTATCCGAACGCAAAATTTTGCGCCGA
AGCACAATGGCAATGGGACGGCGTGAATTTCGAGTTATTGAGGTCGTCTGAAAACCCGGTCGGCGAAGACAATGACCGAA
GCTGCGTCTTGCGCGTCGTTTCCGACGGGCAGGCATTGCTGGTTACGGGCGATTTGGGCGTCAAAGGCGAAGCGGGGCTG
GTAGAACGCTACGGCAGCTCGCTGTACAGCCAGATTTTGATATTGGGACACCACGGCAGCAATACGGCTTCATCCGGCGG
TTTCCTCAACACGGTCGCCCCCAAATACGCCGTCGCCTCCAGCGGCTACGCCAATGCTTACAAACACCCCACTCCCGCCG
TCCAAACCCGCGTCCGCGCACACGGCGCGACTTTGTTGCGGACGGATTTGTCGGGTGCATTGGTATTTGAGCTGGGCGGC
GATGAAGTCTTTAAAGGTCGTCTGAAAAAGGATAAGTTTTATTGGCAGAAAAAGCCGTTTGAGTAA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(209-466)

Metallo-beta-lactamase superfamily (Lactamase_B)

(503-664)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Neisseria gonorrhoeae MS11

72.335

100

0.723