Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   H3L96_RS10545 Genome accession   NZ_CP059565
Coordinates   2209028..2211283 (-) Length   751 a.a.
NCBI ID   WP_009116924.1    Uniprot ID   G4CRS3
Organism   Neisseria wadsworthii strain DSM 22245     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 2204028..2216283
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H3L96_RS10535 (H3L96_10525) modA 2204745..2205494 (-) 750 WP_009116922.1 molybdate ABC transporter substrate-binding protein -
  H3L96_RS10540 (H3L96_10530) - 2205657..2208818 (-) 3162 WP_009116923.1 Ig-like domain-containing protein -
  H3L96_RS10545 (H3L96_10535) comA 2209028..2211283 (-) 2256 WP_009116924.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  H3L96_RS10550 (H3L96_10540) - 2211397..2212272 (-) 876 WP_040667569.1 DMT family transporter -
  H3L96_RS10555 (H3L96_10545) - 2212393..2212824 (-) 432 WP_244963443.1 hypothetical protein -
  H3L96_RS10560 (H3L96_10550) ybaK 2212852..2213337 (-) 486 WP_040667571.1 Cys-tRNA(Pro) deacylase -
  H3L96_RS10565 (H3L96_10555) - 2213420..2213776 (+) 357 WP_009116928.1 RidA family protein -
  H3L96_RS10570 (H3L96_10560) - 2214078..2214692 (-) 615 WP_156792988.1 glutathione S-transferase family protein -
  H3L96_RS10575 (H3L96_10565) pdxA 2214868..2215848 (+) 981 WP_009116930.1 4-hydroxythreonine-4-phosphate dehydrogenase PdxA -

Sequence

Protein


Download         Length: 751 a.a.        Molecular weight: 81765.01 Da        Isoelectric Point: 10.0454

>NTDB_id=470715 H3L96_RS10545 WP_009116924.1 2209028..2211283(-) (comA) [Neisseria wadsworthii strain DSM 22245]
MRFFERCLPAWVVGITASFALPAVPAWYVAAMAGLGLLLAARRSGVAAVLLVALLGAVYGTWRTELVLANQWPVAQVEAN
MLTLKVTGLPQREERWVRFEAQVQDFSGRQWRVQLSDYSLRDWPIGSVWRAKVRVRAPVGEVNLRGFNREAWALANGLSG
TGTVGKERERIGQGQEIGLQQLRAAVSGNWQQVQGFEQGVALMRALSIGEQSALPNRAWQAFRPLGLTHLVSISGLHVSM
VGLLAALLARMVLRRLPFSFKRPRTVMLLVGLSAAFAYALLAGFGVPTQRTVLMLAAFAWIWHSRKGQSVWFAWWAALAA
VLLFDPLAVLGVGTWLSFGLVAALLWVSAWRLEEKGQVVFWRGQYALLLVSLVALGFMFAALPLISSLVNLIAVPWFSWV
LVPLALAASAFPVEPLQMLAAGAGEYTMRALFWLGSWAPEWSMAAAPVSLLWLAVAAVLVALLPRGLGLKPWAFVVLAGF
TFYRPPAVPKQALKIMVWDVGQGLAVSFHTASKTLLFDTGTEAAAQTQLIPSLRAMGVHKLDGAVFSHHDNDHDGGAMLI
RQAFSPATLWAGQPEFYPNALSCHEAEAWDWDGVHFEFLSLSEKAGDDNEQSCVLRVVAAEKALLVTGDLSQRGEQALIS
RYGSGLYSQVLILGHHGSSSASSGAFLNAVAPQYAIASSGFANAYGHPAKAVKTRLRAHGIQLLRTDLQGARLVGFEPEE
ALSLGAERHENKAYWQKKPFGKEAGQNESMP

Nucleotide


Download         Length: 2256 bp        

>NTDB_id=470715 H3L96_RS10545 WP_009116924.1 2209028..2211283(-) (comA) [Neisseria wadsworthii strain DSM 22245]
GTGCGCTTTTTTGAACGCTGTCTGCCTGCGTGGGTGGTTGGAATTACAGCTTCTTTTGCGCTGCCGGCCGTGCCCGCTTG
GTATGTTGCGGCTATGGCAGGTTTGGGTTTGCTGCTTGCTGCGCGGCGTAGTGGTGTGGCGGCTGTGTTGCTGGTGGCAC
TTTTGGGCGCCGTTTACGGTACATGGCGCACAGAGCTCGTGCTGGCAAACCAATGGCCGGTCGCGCAGGTTGAAGCAAAT
ATGCTGACGCTTAAGGTAACGGGCTTACCGCAGCGGGAAGAGCGGTGGGTGCGTTTTGAAGCTCAAGTGCAGGATTTTTC
CGGGCGGCAATGGCGGGTTCAGCTTTCCGATTATTCGCTTCGCGACTGGCCGATAGGCAGTGTGTGGCGGGCGAAAGTGC
GGGTGAGGGCGCCTGTGGGCGAGGTGAATCTGCGTGGGTTTAACCGGGAGGCATGGGCTTTGGCCAATGGATTGAGCGGT
ACGGGAACGGTTGGGAAAGAACGTGAGCGTATCGGGCAGGGACAGGAGATCGGTTTGCAGCAGCTGCGCGCGGCTGTTAG
CGGCAACTGGCAGCAGGTGCAGGGATTTGAACAGGGTGTGGCATTGATGCGGGCTTTGAGTATAGGCGAGCAAAGTGCGC
TGCCGAATCGGGCTTGGCAAGCATTCCGCCCTTTGGGTTTGACGCATTTGGTCAGCATATCCGGCCTGCATGTCAGCATG
GTGGGGTTGCTGGCGGCATTGCTGGCGCGGATGGTGTTGCGCCGTTTGCCGTTTTCATTTAAACGGCCGCGCACGGTGAT
GCTGCTTGTTGGTTTGTCGGCGGCATTTGCTTATGCGCTGCTGGCAGGGTTTGGTGTGCCGACTCAGCGCACGGTGTTGA
TGTTGGCGGCATTTGCCTGGATTTGGCATTCGAGGAAAGGGCAGTCGGTTTGGTTTGCCTGGTGGGCGGCGCTTGCCGCG
GTGTTGTTGTTTGATCCGCTGGCTGTGCTGGGTGTGGGCACATGGCTTTCGTTTGGTTTAGTAGCTGCTTTGCTGTGGGT
AAGTGCTTGGCGGCTGGAAGAAAAAGGACAGGTTGTGTTTTGGCGCGGCCAGTACGCGTTGTTGCTGGTATCTTTGGTGG
CGCTGGGATTTATGTTTGCGGCGTTGCCCTTAATCAGCTCTTTGGTAAATTTGATTGCTGTACCGTGGTTTTCATGGGTG
TTGGTGCCGTTGGCATTGGCGGCTTCTGCTTTTCCTGTTGAGCCTTTGCAAATGCTGGCGGCAGGTGCGGGCGAATATAC
GATGCGGGCATTGTTTTGGCTGGGAAGCTGGGCGCCTGAGTGGAGTATGGCTGCGGCGCCGGTAAGTTTGTTGTGGCTGG
CTGTTGCTGCGGTGTTGGTGGCTTTGTTGCCTCGGGGGCTGGGGCTGAAGCCGTGGGCATTTGTTGTGTTGGCAGGTTTT
ACTTTTTACCGCCCGCCTGCCGTGCCGAAACAGGCTTTGAAGATTATGGTGTGGGATGTCGGACAGGGGCTGGCTGTGAG
TTTTCATACTGCTTCTAAAACGCTGTTGTTTGATACGGGCACGGAAGCAGCGGCGCAAACGCAGTTGATACCGAGCTTGC
GTGCAATGGGTGTGCATAAGCTGGATGGAGCCGTGTTTTCACATCATGATAATGATCACGACGGCGGCGCAATGCTTATC
AGACAGGCATTCAGCCCGGCAACACTGTGGGCGGGGCAACCTGAATTTTACCCAAATGCACTGTCTTGCCATGAGGCGGA
AGCATGGGATTGGGATGGTGTGCATTTTGAATTTTTAAGCCTGTCTGAAAAAGCGGGTGATGACAATGAACAAAGCTGTG
TGTTGCGTGTAGTGGCGGCTGAAAAAGCGTTGCTGGTTACAGGGGATTTGAGCCAGCGGGGTGAGCAGGCATTAATCTCG
CGTTACGGCAGCGGGCTATACAGCCAAGTGCTGATACTCGGCCATCACGGCAGCAGTAGCGCTTCTTCCGGGGCATTTTT
AAACGCGGTTGCACCGCAATATGCTATTGCCTCCAGCGGTTTTGCCAATGCTTACGGGCATCCGGCAAAAGCGGTAAAAA
CACGTTTGCGGGCACATGGCATTCAGCTTTTACGCACCGATTTGCAAGGAGCCCGGCTAGTTGGTTTTGAGCCGGAAGAG
GCTTTATCGCTAGGTGCGGAGCGGCATGAGAACAAAGCATATTGGCAGAAAAAGCCTTTTGGGAAAGAAGCCGGGCAAAA
CGAATCAATGCCGTAG

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(25-166)

Metallo-beta-lactamase superfamily (Lactamase_B)

(509-676)

Competence protein (Competence)

(206-463)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G4CRS3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Neisseria gonorrhoeae MS11

56.157

98.402

0.553