Detailed information NTG0046997

Bioinformatically predicted

Overview

• Name: comB10
• Type: Machinery gene
• Locus tag: HMPREF0462_RS00495
• Genome accession: NC_017375
• Coordinates: 97999..99201 (-)
• Length: 400 a.a.
• NCBI ID: WP_000814200.1
• Uniprot ID: F4D335
• Organism: Helicobacter pylori 83
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 92999..104201

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF0462_RS08880 (HMPREF0462_0095)	-	93009..93221 (-)	213	Protein_88	SMI1/KNR4 family protein	-
HMPREF0462_RS00475 (HMPREF0462_0096)	tnpA	93294..93740 (-)	447	WP_014536385.1	IS200/IS605 family transposase	-
HMPREF0462_RS00480 (HMPREF0462_0098)	-	93792..95074 (+)	1283	Protein_90	RNA-guided endonuclease InsQ/TnpB family protein	-
HMPREF0462_RS00485 (HMPREF0462_0099)	-	95092..95715 (-)	624	Protein_91	hypothetical protein	-
HMPREF0462_RS00490 (HMPREF0462_0100)	-	95728..98015 (-)	2288	Protein_92	collagen-like protein	-
HMPREF0462_RS00495 (HMPREF0462_0102)	comB10	97999..99201 (-)	1203	WP_000814200.1	DNA type IV secretion system protein ComB10	Machinery gene
HMPREF0462_RS00500	-	99198..100868 (-)	1671	Protein_94	TrbG/VirB9 family P-type conjugative transfer protein	-
HMPREF0462_RS00505 (HMPREF0462_0106)	-	100865..101998 (-)	1134	WP_000067667.1	VirB8/TrbF family protein	-
HMPREF0462_RS00510 (HMPREF0462_0107)	-	101991..102125 (-)	135	WP_000738749.1	hypothetical protein	-

Sequence

Protein

• Length: 400 a.a.
• Molecular weight: 44737.43 Da
• Isoelectric Point: 10.0509

>NTDB_id=46997 HMPREF0462_RS00495 WP_000814200.1 97999..99201(-) (comB10) [Helicobacter pylori 83]
MKQSLLKKIGLVIGGFGALMALGLLANKGSNNNNKEEIFQVNESKFPLSDYFFEEVKEEPKKEESPKTITTPQPTAPTTT
NVSTNPIITDYSHLNSNLNKQNDTITHLQQVLQSPPKMKPKLKHTKEQLEFLNTRLKPLEPTKPATKPETEYGVDSFSNL
RYKDIGTNEHKLLRTITADRMIPAFLITPISSQIAGKVTAQVESDIFASMGRAVLIPKGSKVIGYYNNNNQIGQYRLNIA
WTRIITPQGINIMLTNARGADVKGYNGLVGKYISRNFQRYGIPLLTNTLSNGLLIGITSALANQQNKKGDGNPFFGDYLL
MQLTRNTGMGINQIINQMLRQYGAQNPIIIIREGSRVFISPNLDIFIPKPKDGEVLAEFFKEKKPLIKKSNEEVNNEEEI

Nucleotide

• Length: 1203 bp

>NTDB_id=46997 HMPREF0462_RS00495 WP_000814200.1 97999..99201(-) (comB10) [Helicobacter pylori 83]
ATGAAACAATCCTTACTTAAAAAAATCGGCTTAGTTATAGGGGGCTTTGGTGCTTTAATGGCATTAGGATTGCTTGCTAA
TAAAGGTTCAAACAATAACAATAAAGAAGAAATCTTTCAAGTAAATGAGAGTAAATTCCCACTAAGTGATTATTTCTTTG
AAGAAGTCAAAGAAGAACCAAAAAAAGAAGAAAGCCCCAAAACAATAACTACGCCACAACCTACAGCTCCAACTACTACT
AATGTTTCAACTAATCCTATCATTACAGATTATAGTCATCTTAACAGCAATCTCAACAAGCAAAATGACACCATCACGCA
TTTGCAACAAGTCTTACAAAGCCCCCCTAAAATGAAACCTAAATTAAAGCATACTAAAGAGCAATTAGAGTTTTTAAACA
CACGCCTTAAACCTTTAGAACCAACTAAACCAGCCACTAAGCCTGAGACGGAATATGGCGTGGATAGTTTTAGCAATTTA
AGATATAAAGACATCGGCACTAATGAGCATAAGCTCTTAAGAACTATAACCGCTGATAGAATGATACCAGCCTTTTTAAT
CACGCCTATTAGTTCTCAAATCGCTGGAAAAGTAACCGCTCAAGTAGAGAGTGATATTTTTGCTTCTATGGGTAGAGCGG
TGCTAATTCCTAAAGGCTCTAAGGTTATAGGCTATTACAATAACAATAATCAAATTGGGCAATACCGCTTAAACATTGCT
TGGACTAGAATTATCACCCCTCAAGGCATAAATATCATGCTCACTAATGCAAGGGGGGCTGATGTGAAAGGCTATAATGG
CTTAGTAGGCAAATATATTAGCCGAAATTTTCAACGCTATGGTATCCCCTTACTCACTAACACGCTTTCTAATGGGCTTT
TAATAGGAATTACTTCAGCCTTAGCTAATCAACAAAATAAAAAAGGTGATGGCAACCCTTTTTTTGGGGATTACTTGCTT
ATGCAACTCACTAGAAACACAGGTATGGGGATTAACCAAATTATCAATCAAATGCTAAGACAATATGGAGCGCAAAACCC
CATTATCATCATTAGAGAGGGGAGCAGAGTGTTTATTAGTCCTAATTTAGACATCTTTATCCCTAAACCAAAAGATGGGG
AGGTCCTAGCGGAGTTTTTTAAAGAGAAAAAACCGCTAATCAAAAAATCAAACGAGGAAGTTAATAATGAAGAAGAAATC
TAA

Domains

Predicted by InterproScan.

• Bacterial conjugation TrbI-like protein (TrbI) (175-365)

3D structure

• AlphaFold DB: F4D335

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB10	Helicobacter pylori P1	53.181	98.25	0.523