Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/comE3   Type   Machinery gene
Locus tag   HMPREF0462_RS00230 Genome accession   NC_017375
Coordinates   45733..47046 (+) Length   437 a.a.
NCBI ID   WP_000653536.1    Uniprot ID   F4D2P8
Organism   Helicobacter pylori 83     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 40733..52046
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0462_RS00210 (HMPREF0462_0041) crdR 41053..41694 (+) 642 WP_001169802.1 copper response regulator transcription factor CrdR -
  HMPREF0462_RS00215 (HMPREF0462_0042) crdS 41660..42862 (+) 1203 WP_080006302.1 copper-sensing histidine kinase CrdS -
  HMPREF0462_RS00220 (HMPREF0462_0043) - 42865..44259 (+) 1395 WP_000954070.1 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase -
  HMPREF0462_RS00225 (HMPREF0462_0044) - 44270..45736 (+) 1467 WP_000349784.1 replicative DNA helicase -
  HMPREF0462_RS00230 (HMPREF0462_0045) comEC/comE3 45733..47046 (+) 1314 WP_000653536.1 ComEC/Rec2 family competence protein Machinery gene
  HMPREF0462_RS00235 (HMPREF0462_0046) mqnP 47117..47959 (+) 843 WP_229108911.1 menaquinone biosynthesis prenyltransferase MqnP -
  HMPREF0462_RS00240 (HMPREF0462_0047) - 47952..48446 (+) 495 WP_014536371.1 hypothetical protein -
  HMPREF0462_RS00245 (HMPREF0462_0048) - 48459..48962 (+) 504 WP_000953083.1 DUF6115 domain-containing protein -
  HMPREF0462_RS00250 (HMPREF0462_0049) - 48959..49762 (+) 804 WP_000561104.1 phosphatidylserine decarboxylase -
  HMPREF0462_RS00255 (HMPREF0462_0050) nadA 49752..50762 (+) 1011 WP_001141777.1 quinolinate synthase NadA -
  HMPREF0462_RS00260 (HMPREF0462_0051) nadC 50762..51583 (+) 822 WP_000404028.1 carboxylating nicotinate-nucleotide diphosphorylase -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 50275.43 Da        Isoelectric Point: 9.9069

>NTDB_id=46996 HMPREF0462_RS00230 WP_000653536.1 45733..47046(+) (comEC/comE3) [Helicobacter pylori 83]
MKDKTFQGAFELLATPKEYLLCGIILSLLLALNLYLEYLNYQKLDFSKPTSLNAQILLQYPKTKDQKTYFVLKLQSKGMI
FYTTIKEPLKNLQYRHAQFFGKIKPCSFLESLKSCFFQTYSFSLMRKQDFKSHWRHFIDSAHSSALVGNLYRALFIGDSL
NKDLRDRANTLGINHLLAISGFHLGILSASVYFLFSLFYTPLQKRYFPYRNAFYDIGVLVWVFLLGYLLLLNFLPSFFRA
FLMGLLGFLACFFGVRLLSFKLLILACCIAIALLPKLLFSVGFLLSVCGVWYIFLFLKHTQAFFKTSSFLMRSFQVISLS
TLIFLNMLIVAHAFFPMFSPYQLFSIPLGLIFIVFFPLSLFLHAVGLGSLLDGILNMPLTIPTISVFSPLWLLGVHLFLM
ILSVRFFKVYLSMNVLSAGFFLYCCYQYIIMPSLIVG

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=46996 HMPREF0462_RS00230 WP_000653536.1 45733..47046(+) (comEC/comE3) [Helicobacter pylori 83]
TTGAAAGATAAAACTTTTCAGGGGGCGTTTGAACTTCTTGCAACCCCCAAAGAATACTTGTTATGTGGGATTATTTTAAG
CCTTTTGTTAGCACTCAATCTTTATTTAGAATACTTGAATTACCAAAAGCTTGATTTTTCAAAACCCACAAGCTTAAACG
CTCAAATCTTGTTGCAATACCCCAAAACTAAAGATCAAAAAACCTATTTTGTTTTAAAGCTCCAATCAAAGGGCATGATC
TTTTATACCACCATTAAAGAGCCTTTAAAGAACCTCCAATACCGCCATGCGCAATTTTTTGGCAAAATCAAACCTTGCTC
ATTTTTGGAGTCTTTAAAATCATGCTTTTTTCAAACTTATTCTTTTTCTTTAATGCGAAAACAAGATTTCAAATCGCATT
GGCGCCATTTCATTGATAGCGCTCATTCAAGCGCTTTAGTGGGTAATTTATACCGAGCGTTGTTTATAGGGGATAGCTTG
AATAAAGACTTAAGAGATAGGGCTAACACGCTAGGGATCAACCACTTACTAGCCATTAGCGGATTCCATTTAGGGATTTT
GAGCGCGAGCGTGTATTTCCTTTTCTCTCTTTTTTATACCCCCTTACAAAAACGCTATTTCCCTTATAGGAACGCTTTTT
ATGATATAGGGGTTTTGGTGTGGGTTTTTTTGCTAGGGTATTTGTTGCTATTGAATTTTTTACCCTCTTTTTTCAGGGCG
TTTTTAATGGGCTTATTAGGGTTTTTGGCATGCTTTTTTGGGGTAAGGCTTTTGAGTTTTAAACTTTTGATTTTAGCGTG
CTGTATCGCTATAGCGTTACTCCCTAAATTGCTTTTTAGCGTGGGGTTTTTGCTTTCTGTTTGTGGGGTGTGGTATATCT
TTTTATTTTTAAAACACACTCAAGCCTTTTTTAAAACCTCTTCTTTTTTGATGCGATCTTTTCAGGTCATAAGCTTAAGC
ACGCTAATTTTTTTGAACATGCTCATCGTTGCGCATGCCTTTTTCCCTATGTTTTCGCCCTACCAACTCTTTAGCATTCC
TTTAGGCTTGATTTTTATCGTGTTTTTCCCTTTGAGTTTGTTTTTGCATGCTGTGGGTTTGGGGTCTTTGCTGGATGGTA
TTTTAAACATGCCTTTAACAATCCCTACGATTTCGGTTTTTTCGCCTTTATGGCTTTTGGGGGTGCATTTATTTTTAATG
ATTCTAAGCGTGCGTTTTTTTAAAGTTTATTTAAGCATGAATGTTTTAAGCGCAGGCTTTTTCTTGTATTGTTGCTATCA
ATATATTATAATGCCTAGTTTAATTGTAGGTTAG

Domains

Predicted by InterproScan.

Competence protein (Competence)

(159-400)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F4D2P8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/comE3 Helicobacter pylori 26695

94.05

100

0.941

Multiple sequence alignment