Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB2   Type   Machinery gene
Locus tag   HPGAM_RS07240 Genome accession   NC_017371
Coordinates   1519414..1519698 (-) Length   94 a.a.
NCBI ID   WP_000413637.1    Uniprot ID   A0AB72ZV75
Organism   Helicobacter pylori Gambia94/24     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1514414..1524698
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPGAM_RS07215 (HPGAM_07495) - 1515049..1516185 (-) 1137 WP_000067689.1 VirB8/TrbF family protein -
  HPGAM_RS08990 (HPGAM_07500) - 1516178..1516318 (-) 141 WP_000789929.1 hypothetical protein -
  HPGAM_RS07225 (HPGAM_07505) - 1516315..1518891 (-) 2577 WP_000893951.1 VirB4 family type IV secretion/conjugal transfer ATPase -
  HPGAM_RS07230 (HPGAM_07510) - 1518891..1519127 (-) 237 WP_001168536.1 hypothetical protein -
  HPGAM_RS07235 (HPGAM_07515) comB3 1519139..1519402 (-) 264 WP_001177718.1 hypothetical protein Machinery gene
  HPGAM_RS07240 (HPGAM_07520) comB2 1519414..1519698 (-) 285 WP_000413637.1 TrbC/VirB2 family protein Machinery gene
  HPGAM_RS07245 (HPGAM_07525) - 1519686..1520174 (-) 489 WP_000571144.1 hypothetical protein -
  HPGAM_RS07250 (HPGAM_07530) - 1520167..1520397 (-) 231 WP_000189080.1 hypothetical protein -
  HPGAM_RS07255 (HPGAM_07535) - 1520400..1521188 (-) 789 WP_001140581.1 hypothetical protein -
  HPGAM_RS08580 (HPGAM_07540) - 1521166..1521714 (-) 549 WP_014536024.1 restriction endonuclease subunit S -
  HPGAM_RS07265 (HPGAM_07545) purU 1521756..1522637 (-) 882 WP_000889117.1 formyltetrahydrofolate deformylase -
  HPGAM_RS07270 (HPGAM_07550) sppA 1522640..1523518 (-) 879 WP_000269572.1 signal peptide peptidase SppA -
  HPGAM_RS07275 (HPGAM_07555) - 1523589..1523849 (+) 261 WP_000752265.1 hypothetical protein -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10753.05 Da        Isoelectric Point: 10.7837

>NTDB_id=46945 HPGAM_RS07240 WP_000413637.1 1519414..1519698(-) (comB2) [Helicobacter pylori Gambia94/24]
MEKLRHFRKLIAFLGFSPLLLQADMTTFFNSIEQQLTSPTAKGILMVIFLGLAIFIWKNLDRWKEILMTVLAIAIGAAIF
FKAPALANWFMSIF

Nucleotide


Download         Length: 285 bp        

>NTDB_id=46945 HPGAM_RS07240 WP_000413637.1 1519414..1519698(-) (comB2) [Helicobacter pylori Gambia94/24]
ATGGAAAAATTAAGGCATTTTAGAAAGCTTATCGCCTTTTTAGGTTTTTCACCTCTTTTATTACAAGCGGATATGACTAC
CTTTTTTAATTCCATTGAACAACAGCTCACTAGCCCTACGGCTAAAGGCATTTTAATGGTTATTTTTTTAGGACTTGCTA
TTTTTATATGGAAAAACTTAGATAGATGGAAAGAAATTTTAATGACCGTGCTTGCTATTGCAATTGGTGCTGCAATCTTT
TTTAAAGCCCCAGCCTTAGCTAACTGGTTTATGAGTATTTTTTAA

Domains

Predicted by InterproScan.

TrbC/VIRB2 pilin (TrbC)

(6-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB2 Helicobacter pylori 26695

57.778

95.745

0.553

Multiple sequence alignment