Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HPGAM_RS04100 Genome accession   NC_017371
Coordinates   857901..859685 (+) Length   594 a.a.
NCBI ID   WP_000774392.1    Uniprot ID   -
Organism   Helicobacter pylori Gambia94/24     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 852901..864685
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPGAM_RS04070 (HPGAM_04210) motB 853621..854394 (+) 774 WP_001085371.1 flagellar motor protein MotB -
  HPGAM_RS04075 (HPGAM_04215) - 854391..854837 (+) 447 WP_001081239.1 hypothetical protein -
  HPGAM_RS04080 (HPGAM_04220) - 854951..856612 (+) 1662 WP_000901293.1 glycine betaine ABC transporter substrate-binding protein -
  HPGAM_RS04085 (HPGAM_04225) - 856615..857265 (+) 651 WP_000659393.1 ATP-binding cassette domain-containing protein -
  HPGAM_RS04090 - 857268..857447 (-) 180 WP_000468798.1 hypothetical protein -
  HPGAM_RS04095 (HPGAM_04230) - 857439..857900 (+) 462 WP_000437175.1 hypothetical protein -
  HPGAM_RS04100 (HPGAM_04235) uvrC 857901..859685 (+) 1785 WP_000774392.1 excinuclease ABC subunit UvrC Machinery gene
  HPGAM_RS04105 (HPGAM_04240) - 859696..860961 (+) 1266 WP_000746761.1 homoserine dehydrogenase -
  HPGAM_RS04110 (HPGAM_04245) - 860961..861305 (+) 345 WP_001211714.1 YraN family protein -
  HPGAM_RS04115 (HPGAM_04250) trxA 861397..861717 (+) 321 WP_000020193.1 thioredoxin -
  HPGAM_RS04120 (HPGAM_04255) trxB 861723..862658 (+) 936 WP_000564386.1 thioredoxin-disulfide reductase -
  HPGAM_RS04125 (HPGAM_04260) - 863018..863839 (+) 822 WP_001263360.1 glycosyltransferase family 25 protein -
  HPGAM_RS04130 (HPGAM_04265) - 864051..864299 (-) 249 WP_000790555.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68778.91 Da        Isoelectric Point: 9.7560

>NTDB_id=46939 HPGAM_RS04100 WP_000774392.1 857901..859685(+) (uvrC) [Helicobacter pylori Gambia94/24]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNSRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGSKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNEVLKELQEFISHQYSKKIALNIPKKGDKLALIEIAMKNAQEIFSQEKTSSEDRILEETRSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYDQMSELLTRRALDFAKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLRKRK

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=46939 HPGAM_RS04100 WP_000774392.1 857901..859685(+) (uvrC) [Helicobacter pylori Gambia94/24]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAACAGCAGTGGGGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTACATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCGTAATAATGAAATCACGCCCA
ATTCTCGCACCAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTGATCAAGCAGCTCAAGCCTAAATATAATATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGTCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCTTTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACTAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAATTTGCGTTTTGAAGAAGCCCTAATTTACAGGGATAGGATAGCTAAAATCCAAAAAATC
GCCCCCTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCCTTTTATGGTGGGAACAATAAGGCGGT
GTTAGTGAAAATGTTCATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAGC
GCTTGCTCTAATGAAGTGCTTAAAGAATTGCAAGAGTTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAATATCCC
TAAAAAGGGCGATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAGGAAAAAACCTCTA
GTGAAGATCGGATTTTAGAAGAAACGCGATCGCTCTTCAATTTAGAGTGCGTGCCTTATAGGGTAGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCATTTCAAAAAAACTCTTATCGGCG
TTACCATTTAAAAGGCTCTAACGAATACGATCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTGATAGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTGGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCTAGCAATACTTTTAAATTACTCCCTAGCGACAAACGCTTGCAATGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAGAAAACGAAAATAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.121

99.832

0.96

Multiple sequence alignment