Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HPGAM_RS00100 Genome accession   NC_017371
Coordinates   14472..16835 (+) Length   787 a.a.
NCBI ID   WP_000890474.1    Uniprot ID   -
Organism   Helicobacter pylori Gambia94/24     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 9472..21835
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPGAM_RS00070 (HPGAM_00055) groES 9500..9856 (-) 357 WP_000671962.1 co-chaperone GroES -
  HPGAM_RS00075 (HPGAM_00060) dnaG 10133..11812 (+) 1680 WP_000601597.1 DNA primase -
  HPGAM_RS00080 (HPGAM_00065) - 11809..12861 (+) 1053 WP_000809445.1 MnmA/TRMU family protein -
  HPGAM_RS00085 (HPGAM_00070) - 12954..13781 (+) 828 WP_001154925.1 DUF5718 family protein -
  HPGAM_RS00090 (HPGAM_00075) comB2 13926..14207 (+) 282 WP_001277276.1 TrbC/VirB2 family protein Machinery gene
  HPGAM_RS00095 (HPGAM_00080) comB3 14207..14470 (+) 264 WP_000584953.1 hypothetical protein Machinery gene
  HPGAM_RS00100 (HPGAM_00085) comB4 14472..16835 (+) 2364 WP_000890474.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HPGAM_RS00105 (HPGAM_00090) - 17140..18480 (+) 1341 WP_014535910.1 COG3014 family protein -
  HPGAM_RS00110 (HPGAM_00095) cheV1 18586..19551 (+) 966 WP_000785452.1 chemotaxis protein CheV1 -
  HPGAM_RS00115 (HPGAM_00100) nspC 19548..20765 (+) 1218 WP_000760923.1 carboxynorspermidine decarboxylase -
  HPGAM_RS00120 (HPGAM_00105) lpxE 20804..21337 (-) 534 WP_223823358.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90146.42 Da        Isoelectric Point: 7.7024

>NTDB_id=46927 HPGAM_RS00100 WP_000890474.1 14472..16835(+) (comB4) [Helicobacter pylori Gambia94/24]
MLEKLLGAIKQKVSNYFLGALPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDYQQSIQSDSQYLQAILNQFENKEVYENQYFLVLESTHSLHGVLEHKKKSFMHANRENFKDILS
YKAHFLQETFKSLEIQLKNYAPKLLNSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAVGALLYQETPLDIIFSIEPMSAHKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNVLIKASSLEDLDAQTSLILGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLVIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTEFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMLDLAPSRDKEALEDMNAISGAIKSLYETLYPKDFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSNAFLNVINLDAITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHNFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLEGLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=46927 HPGAM_RS00100 WP_000890474.1 14472..16835(+) (comB4) [Helicobacter pylori Gambia94/24]
ATGTTAGAAAAGCTTTTGGGCGCTATCAAACAAAAAGTTTCAAACTATTTTTTAGGGGCTTTGCCTAAAAGCTATTCAAT
GAGTGAAGAAAACAACATTTTAGGCTTGTATGATGAGCATTTTTTACTCACTAAAAACGAAAACTTAGTGGGTATCCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACCGAGCGTCAGATGGCGTTGGAT
TCTTTAGAAAAAGTCGTGGCGCGCCTGGTGGTTAAAAGGCGTAAAATTGATTATCAACAAAGCATTCAATCTGACTCTCA
ATACTTGCAAGCGATTTTGAATCAGTTTGAAAACAAAGAAGTGTATGAGAATCAGTATTTTTTAGTTTTAGAAAGTACGC
ATTCCTTACATGGCGTTTTAGAGCATAAGAAAAAATCTTTCATGCACGCTAATAGAGAAAATTTTAAGGATATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTTAAAAGCTTAGAAATCCAGCTCAAAAACTATGCCCCCAAACTCTTAAACTC
TAAAGAGGTTTTGAATTTTTATGCGGAATACATTAACGGGTTTGATCTCCCTTTAAAGCCTCTAGTAGGAGGGTATTTGA
GCGATAGCTATATCGCTAGTTCTATCACTTTTGAAAAAGATTATTTCATTCAAGAAAGCTTTAATCAAAAAACCTACAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAACGCATCACTTCTATAGCGGTGGGAGCGCTTTTATACCAAGAAACGCC
TTTGGATATTATCTTTTCCATAGAGCCTATGAGCGCGCATAAAACGCTGAGTTTTTTAAAAGAGAGAGCCAAGTTTAGCA
TGTCCAATCTTGTTAAAAACGAGCTATTAGAATACCAGGAATTAGTCAAAACCAAACGCTTATCCATGCAAAAATTCGCC
CTAAACGTTCTTATCAAAGCCTCCAGTTTGGAGGATTTAGACGCTCAAACGAGCTTAATTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCATTTAAACC
ACCGCTTGCGTTTTTTGACCTCTAAAGCCCTAGCGTGTTTGATGGTGTTTGAAAGGCAAAATTTAGGCTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAATAACGCTAAAGAAATCGCCAGAGTGAATGGGCATACTTTAGTTATAGGGGCAACCGGAAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTAAAATACCAGAACATGCGCCTTTTAGCCTTTGACAGGATGCAAGGGCTG
TATTCTTTCACCGAATTTTTTAAAGGGCATTACCATGACGGCCAATCTTTTAGCATTAACCCCTTTTGTTTAGAGCCTAA
TTTACAGAATTTAGAATTTTTGCAATCCTTTTTTTTGAGCATGTTGGATCTCGCCCCTTCAAGGGATAAAGAAGCCTTAG
AAGACATGAATGCGATTTCTGGTGCGATTAAGAGCCTTTATGAGACCCTATACCCCAAAGATTTTAGTTTGCTAGACTTT
AAAGAAACGCTTAAAAGAACTTCATCTAACCAACTGGGCTTGAGCTTGGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCGTTCAACTCCAACGCTTTTTTAAACGTGATAAACCTAGATGCGATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTACTTGTTTTATAAGATCTTAGAAGAATCCAGGAAAAACGACAGCGGCTTTTTGGTTTTTTTAGAC
GAATTTAAATCCTATGTGGAAAACGATTTGTTGAACACTAAAATCAACGCTTTAATCACGCAAGCTAGGAAAGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGACATTTACCAACTCAGCGGGGTCAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTTATTTTGTATCCGCAAAAAAACGCTAGGGAGTTGAAACACAATTTCAATGTGCCTTTGAGCGAAACTGAAATTTCA
TTTTTAGAAAACACCCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAATGGGAGCTCTAACATGATTGACGT
GAGTTTGGAGGGCTTGGGGCGTTATTTGAAAATCTTTAATTCGGATTCTAGTCATGTCAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGTTAG

Domains

Predicted by InterproScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

97.078

100

0.971

Multiple sequence alignment