Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HPF16_RS02740 Genome accession   NC_017368
Coordinates   545466..547250 (-) Length   594 a.a.
NCBI ID   WP_000774337.1    Uniprot ID   -
Organism   Helicobacter pylori F16     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 540466..552250
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPF16_RS02710 (HPF16_0533) - 541053..541301 (+) 249 WP_000790557.1 RNA-binding protein -
  HPF16_RS02715 (HPF16_0534) - 541507..542328 (-) 822 WP_001263434.1 glycosyltransferase family 25 protein -
  HPF16_RS02720 (HPF16_0535) trxB 542495..543430 (-) 936 WP_000564421.1 thioredoxin-disulfide reductase -
  HPF16_RS02725 (HPF16_0536) trxA 543436..543756 (-) 321 WP_000020199.1 thioredoxin -
  HPF16_RS02730 (HPF16_0537) - 543845..544189 (-) 345 WP_001211650.1 YraN family protein -
  HPF16_RS02735 (HPF16_0538) - 544190..545455 (-) 1266 WP_000746791.1 homoserine dehydrogenase -
  HPF16_RS02740 (HPF16_0539) uvrC 545466..547250 (-) 1785 WP_000774337.1 excinuclease ABC subunit UvrC Machinery gene
  HPF16_RS02745 (HPF16_0540) - 547251..547712 (-) 462 WP_000437148.1 hypothetical protein -
  HPF16_RS02750 (HPF16_0541) - 547704..547883 (+) 180 WP_000468795.1 hypothetical protein -
  HPF16_RS02755 (HPF16_0542) - 547895..548536 (-) 642 WP_000659438.1 ABC transporter ATP-binding protein -
  HPF16_RS02760 (HPF16_0543) - 548538..550094 (-) 1557 WP_000992666.1 ABC transporter permease/substrate-binding protein -
  HPF16_RS02765 (HPF16_0544) - 550194..550631 (-) 438 WP_001031792.1 hypothetical protein -
  HPF16_RS02770 (HPF16_0545) motB 550635..551402 (-) 768 WP_001085288.1 flagellar motor protein MotB -
  HPF16_RS02775 (HPF16_0546) motA 551405..552178 (-) 774 WP_000366176.1 flagellar motor stator protein MotA -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68893.31 Da        Isoelectric Point: 9.7121

>NTDB_id=46914 HPF16_RS02740 WP_000774337.1 545466..547250(-) (uvrC) [Helicobacter pylori F16]
MADLLSSLKNLSHNSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNCRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDV
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDFKAYRSKGGAKDIIHTARDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=46914 HPF16_RS02740 WP_000774337.1 545466..547250(-) (uvrC) [Helicobacter pylori F16]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAATAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAGTT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGTTATTTTTCTGTCCGCAATAATGAAATCACGCCCA
ATTGTCGCGCAAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTAGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCCATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCTGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCACCAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAGGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGTA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTTTAAAGCTTATCGCTCTAAAGGGGGTGCTAAAGACATTAT
CCACACCGCTAGAGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAATGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCTGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.801

100

0.968

Multiple sequence alignment