Detailed information NTG0468834

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: HU024_RS00065
• Genome accession: NZ_CP059344
• Coordinates: 13610..14773 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain K01
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 8610..19773

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HU024_RS00045 (HU024_00045)	-	9050..10246 (+)	1197	WP_032876154.1	glycosyltransferase	-
HU024_RS00050 (HU024_00050)	-	10379..11455 (+)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
HU024_RS00055 (HU024_00055)	-	11554..12735 (-)	1182	WP_032876157.1	LCP family protein	-
HU024_RS00060 (HU024_00060)	-	12740..13387 (-)	648	WP_007614107.1	YigZ family protein	-
HU024_RS00065 (HU024_00065)	degS	13610..14773 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
HU024_RS00070 (HU024_00070)	degU	14850..15539 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
HU024_RS00075 (HU024_00075)	-	15637..16485 (+)	849	WP_032876160.1	DegV family protein	-
HU024_RS00080 (HU024_00080)	comFA	16594..17979 (+)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
HU024_RS00085 (HU024_00085)	-	18037..18321 (+)	285	WP_003151389.1	late competence development ComFB family protein	-
HU024_RS00090 (HU024_00090)	comFC	18327..19016 (+)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
HU024_RS00095 (HU024_00095)	-	19090..19509 (+)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=468834 HU024_RS00065 WP_007407484.1 13610..14773(+) (degS) [Bacillus velezensis strain K01]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=468834 HU024_RS00065 WP_007407484.1 13610..14773(+) (degS) [Bacillus velezensis strain K01]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951