Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HPF32_RS04045 Genome accession   NC_017366
Coordinates   851370..853154 (+) Length   594 a.a.
NCBI ID   WP_000774362.1    Uniprot ID   -
Organism   Helicobacter pylori F32     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 846370..858154
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPF32_RS04015 (HPF32_0783) motB 847048..847821 (+) 774 WP_001085359.1 flagellar motor protein MotB -
  HPF32_RS04020 (HPF32_0784) - 847827..848264 (+) 438 WP_001875641.1 hypothetical protein -
  HPF32_RS04025 (HPF32_0785) - 848419..850080 (+) 1662 WP_001139664.1 ABC transporter permease/substrate-binding protein -
  HPF32_RS04030 (HPF32_0786) - 850084..850725 (+) 642 WP_000665989.1 ATP-binding cassette domain-containing protein -
  HPF32_RS04035 (HPF32_0787) - 850737..850916 (-) 180 WP_000468796.1 hypothetical protein -
  HPF32_RS04040 (HPF32_0788) - 850908..851369 (+) 462 WP_000437189.1 hypothetical protein -
  HPF32_RS04045 (HPF32_0789) uvrC 851370..853154 (+) 1785 WP_000774362.1 excinuclease ABC subunit UvrC Machinery gene
  HPF32_RS04050 (HPF32_0790) - 853165..854430 (+) 1266 WP_000746786.1 homoserine dehydrogenase -
  HPF32_RS04055 (HPF32_0791) - 854431..854775 (+) 345 WP_001211683.1 YraN family protein -
  HPF32_RS04060 (HPF32_0792) trxA 854864..855184 (+) 321 WP_000020200.1 thioredoxin -
  HPF32_RS04065 (HPF32_0793) trxB 855190..856125 (+) 936 WP_000564372.1 thioredoxin-disulfide reductase -
  HPF32_RS04070 (HPF32_0794) - 856432..857253 (+) 822 WP_001263431.1 glycosyltransferase family 25 protein -
  HPF32_RS04075 (HPF32_0795) - 857458..857706 (-) 249 WP_000790564.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68804.11 Da        Isoelectric Point: 9.7098

>NTDB_id=46872 HPF32_RS04045 WP_000774362.1 851370..853154(+) (uvrC) [Helicobacter pylori F32]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNHRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDV
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=46872 HPF32_RS04045 WP_000774362.1 851370..853154(+) (uvrC) [Helicobacter pylori F32]
ATGGCTGATTTGTTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGTTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ATCATCGCACCAGCTTACGAATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTAATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCCTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATAGCGGGAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCTATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCCCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGACAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGTA
AGCCACCATGCCAACAGCCAATGCGTGGGAGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGTAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGAGGCGCTAAAGACATTAT
CCATACACCTAGCGATACTTTTAAGTTGCTCCCTAGCGACAAGCGCTTGCAATGGGTTCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCACTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCTGTTTTAAAAAAACGGATTTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.643

100

0.976

Multiple sequence alignment