Detailed information
Bioinformatically predicted
Overview
| Name | comH | Type | Machinery gene |
| Locus tag | HPLT_RS07355 | Genome accession | NC_017362 |
| Coordinates | 1508954..1510393 (-) | Length | 479 a.a. |
| NCBI ID | WP_000748985.1 | Uniprot ID | - |
| Organism | Helicobacter pylori Lithuania75 | ||
| Function | import of DNA into the periplasm (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1511202..1590520 | 1508954..1510393 | flank | 809 |
Gene organization within MGE regions
Location: 1508954..1590520
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HPLT_RS07355 (HPLT_07600) | comH | 1508954..1510393 (-) | 1440 | WP_000748985.1 | hypothetical protein | Machinery gene |
| HPLT_RS07365 (HPLT_07605) | dnaA | 1510614..1511981 (-) | 1368 | WP_000380603.1 | chromosomal replication initiator protein DnaA | - |
| HPLT_RS07370 (HPLT_07610) | - | 1512134..1512676 (+) | 543 | WP_000923021.1 | hypothetical protein | - |
| HPLT_RS07375 (HPLT_07615) | - | 1512719..1512958 (+) | 240 | WP_000461837.1 | DUF2443 domain-containing protein | - |
| HPLT_RS07380 (HPLT_07620) | glmS | 1512959..1514752 (+) | 1794 | WP_000334382.1 | glutamine--fructose-6-phosphate transaminase (isomerizing) | - |
| HPLT_RS07385 (HPLT_07625) | thyX | 1514775..1515401 (+) | 627 | WP_000451941.1 | FAD-dependent thymidylate synthase | - |
| HPLT_RS08390 (HPLT_07645) | - | 1516029..1516654 (-) | 626 | Protein_1418 | restriction endonuclease subunit S | - |
| HPLT_RS07395 (HPLT_07650) | - | 1517467..1519500 (+) | 2034 | WP_000886950.1 | relaxase/mobilization nuclease domain-containing protein | - |
| HPLT_RS07400 (HPLT_07655) | - | 1520655..1521722 (+) | 1068 | WP_000933799.1 | tyrosine-type recombinase/integrase | - |
| HPLT_RS07405 (HPLT_07660) | - | 1522039..1522842 (-) | 804 | WP_000009095.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| HPLT_RS07410 (HPLT_07665) | - | 1522814..1523065 (-) | 252 | WP_000006537.1 | hypothetical protein | - |
| HPLT_RS07415 | - | 1523265..1524279 (+) | 1015 | Protein_1423 | hypothetical protein | - |
| HPLT_RS07420 | - | 1524284..1525561 (-) | 1278 | Protein_1424 | hypothetical protein | - |
| HPLT_RS07425 (HPLT_07695) | - | 1525558..1526820 (-) | 1263 | WP_001008751.1 | type IV secretion system protein | - |
| HPLT_RS08770 | - | 1526817..1528249 (-) | 1433 | Protein_1426 | hypothetical protein | - |
| HPLT_RS07440 | - | 1528259..1530136 (-) | 1878 | Protein_1427 | hypothetical protein | - |
| HPLT_RS07445 (HPLT_07720) | - | 1530136..1530450 (-) | 315 | Protein_1428 | hypothetical protein | - |
| HPLT_RS07455 (HPLT_07730) | - | 1530984..1531745 (-) | 762 | WP_000841050.1 | transposase | - |
| HPLT_RS07460 (HPLT_07735) | - | 1531732..1532610 (-) | 879 | WP_000180576.1 | hypothetical protein | - |
| HPLT_RS07465 (HPLT_07740) | - | 1532627..1533508 (-) | 882 | WP_000781015.1 | hypothetical protein | - |
| HPLT_RS07470 (HPLT_07745) | - | 1533563..1533889 (-) | 327 | WP_001146133.1 | hypothetical protein | - |
| HPLT_RS08570 | - | 1533893..1534464 (-) | 572 | Protein_1433 | hypothetical protein | - |
| HPLT_RS07480 | - | 1534447..1535201 (-) | 755 | Protein_1434 | ArdC family protein | - |
| HPLT_RS08575 (HPLT_07765) | - | 1535202..1535366 (-) | 165 | WP_000189760.1 | hypothetical protein | - |
| HPLT_RS07485 (HPLT_07770) | - | 1536003..1536671 (+) | 669 | WP_000150823.1 | ParA family protein | - |
| HPLT_RS07490 (HPLT_07775) | - | 1536718..1537095 (+) | 378 | WP_000365707.1 | hypothetical protein | - |
| HPLT_RS07495 (HPLT_07780) | - | 1537073..1537737 (+) | 665 | Protein_1438 | hypothetical protein | - |
| HPLT_RS07500 (HPLT_07785) | - | 1537811..1538615 (-) | 805 | Protein_1439 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| HPLT_RS07505 (HPLT_07790) | - | 1538585..1539055 (-) | 471 | WP_000965788.1 | hypothetical protein | - |
| HPLT_RS07510 (HPLT_07795) | - | 1539110..1541170 (-) | 2061 | WP_001066146.1 | type IA DNA topoisomerase | - |
| HPLT_RS07515 (HPLT_07800) | - | 1541183..1541566 (-) | 384 | WP_000410259.1 | hypothetical protein | - |
| HPLT_RS07520 (HPLT_07805) | - | 1541635..1541886 (-) | 252 | WP_001105124.1 | hypothetical protein | - |
| HPLT_RS08815 (HPLT_07810) | - | 1541966..1542091 (-) | 126 | WP_014535104.1 | hypothetical protein | - |
| HPLT_RS07530 (HPLT_07815) | - | 1542212..1550812 (-) | 8601 | WP_000323618.1 | SNF2-related protein | - |
| HPLT_RS07535 (HPLT_07820) | - | 1550832..1551365 (-) | 534 | Protein_1446 | conjugal transfer protein TraG | - |
| HPLT_RS07540 (HPLT_07825) | - | 1551357..1553102 (+) | 1746 | Protein_1447 | UvrB domain 3-containing protein | - |
| HPLT_RS07545 (HPLT_07830) | - | 1553102..1553809 (+) | 708 | WP_000995238.1 | SprT family zinc-dependent metalloprotease | - |
| HPLT_RS07550 | - | 1553900..1556425 (-) | 2526 | Protein_1449 | TonB-dependent receptor family protein | - |
| HPLT_RS07555 (HPLT_07845) | rocF | 1556774..1557742 (-) | 969 | WP_000604407.1 | arginase | - |
| HPLT_RS07560 (HPLT_07850) | - | 1557946..1559088 (+) | 1143 | WP_000152124.1 | alanine dehydrogenase | - |
| HPLT_RS07565 (HPLT_07855) | - | 1559206..1560972 (+) | 1767 | WP_001062512.1 | DUF262 domain-containing protein | - |
| HPLT_RS07570 (HPLT_07860) | - | 1560983..1561711 (-) | 729 | WP_000713144.1 | outer membrane protein | - |
| HPLT_RS07575 (HPLT_07865) | - | 1561897..1562751 (+) | 855 | WP_014535106.1 | NAD(+)/NADH kinase | - |
| HPLT_RS07580 (HPLT_07870) | - | 1562773..1564347 (+) | 1575 | WP_001204436.1 | DNA repair protein RecN | - |
| HPLT_RS07585 (HPLT_07875) | - | 1564344..1565651 (+) | 1308 | WP_000667833.1 | NFACT family protein | - |
| HPLT_RS07590 (HPLT_07880) | - | 1565670..1565966 (+) | 297 | WP_000539112.1 | hypothetical protein | - |
| HPLT_RS07595 (HPLT_07885) | - | 1566058..1566306 (+) | 249 | Protein_1458 | hypothetical protein | - |
| HPLT_RS07600 (HPLT_07890) | - | 1566296..1566883 (+) | 588 | WP_000506587.1 | hypothetical protein | - |
| HPLT_RS07605 (HPLT_07895) | - | 1566905..1567465 (+) | 561 | Protein_1460 | DNA cytosine methyltransferase | - |
| HPLT_RS07610 (HPLT_07900) | - | 1567566..1567769 (-) | 204 | WP_014535108.1 | hypothetical protein | - |
| HPLT_RS07615 (HPLT_07905) | - | 1567769..1568641 (-) | 873 | WP_000384724.1 | class 1 fructose-bisphosphatase | - |
| HPLT_RS07620 (HPLT_07910) | rpe | 1568712..1569365 (+) | 654 | WP_000861495.1 | ribulose-phosphate 3-epimerase | - |
| HPLT_RS07625 (HPLT_07915) | - | 1569343..1570206 (+) | 864 | WP_001122172.1 | 3'-5' exonuclease | - |
| HPLT_RS07630 (HPLT_07920) | - | 1570517..1571131 (-) | 615 | Protein_1465 | hypothetical protein | - |
| HPLT_RS07635 (HPLT_07925) | tsf | 1571192..1572259 (-) | 1068 | WP_000014434.1 | translation elongation factor Ts | - |
| HPLT_RS07640 (HPLT_07930) | rpsB | 1572259..1573053 (-) | 795 | WP_000258276.1 | 30S ribosomal protein S2 | - |
| HPLT_RS07645 (HPLT_07935) | - | 1573303..1576158 (+) | 2856 | WP_000380063.1 | RecB-like helicase | - |
| HPLT_RS07650 (HPLT_07940) | nhaA | 1576182..1577498 (+) | 1317 | WP_001049651.1 | sodium/proton antiporter NhaA | - |
| HPLT_RS07655 (HPLT_07945) | yajC | 1577546..1577929 (+) | 384 | WP_000529776.1 | preprotein translocase subunit YajC | - |
| HPLT_RS07660 (HPLT_07950) | secD | 1577926..1579506 (+) | 1581 | WP_000765464.1 | protein translocase subunit SecD | - |
| HPLT_RS07665 (HPLT_07955) | secF | 1579515..1580486 (+) | 972 | WP_000418596.1 | protein translocase subunit SecF | - |
| HPLT_RS07670 (HPLT_07960) | - | 1580496..1580834 (+) | 339 | WP_000383764.1 | DUF6394 family protein | - |
| HPLT_RS07675 (HPLT_07965) | leuS | 1580844..1583264 (+) | 2421 | WP_000348284.1 | leucine--tRNA ligase | - |
| HPLT_RS07680 (HPLT_07970) | lptE | 1583261..1583773 (+) | 513 | WP_001264889.1 | LPS assembly lipoprotein LptE | - |
| HPLT_RS07685 (HPLT_07975) | - | 1583763..1584938 (+) | 1176 | WP_000798436.1 | bifunctional folylpolyglutamate synthase/dihydrofolate synthase | - |
| HPLT_RS07690 (HPLT_07980) | csd2 | 1584938..1585864 (+) | 927 | WP_001136030.1 | M23B family cell shape-determining DD-metalloendopeptidase Csd2 | - |
| HPLT_RS07695 (HPLT_07985) | csd1 | 1585873..1586811 (+) | 939 | WP_000478047.1 | peptidoglycan DD-metalloendopeptidase Csd1 | - |
| HPLT_RS07700 (HPLT_07990) | - | 1586730..1587140 (+) | 411 | WP_014535109.1 | bactofilin family protein | - |
| HPLT_RS07705 (HPLT_07995) | mfd | 1587144..1590143 (+) | 3000 | WP_000616338.1 | transcription-repair coupling factor | - |
Sequence
Protein
Download Length: 479 a.a. Molecular weight: 54860.78 Da Isoelectric Point: 6.8237
>NTDB_id=46840 HPLT_RS07355 WP_000748985.1 1508954..1510393(-) (comH) [Helicobacter pylori Lithuania75]
MKKSLCLSFFLTFSNPLQALVIELLEEIKTSPHKGTFKAKVLDSKEPRQVLGVYNISPHKKLTLTITHISTAIVYQPLDE
KLSLETTLNPNRPTIPRNTQIVFSSKELKESHSHQMPSLNAPMQKPQNKPHSSQQPSQNFSYPEPKLGSKNSKNSLLQPL
AIPSKISPTNETQTPTNDTKPPLKHSSEDQENNLFITPPTEKTLPNNTSNTGISENNESNENRDNVEKQAIRDPNVKEFA
CGKWVYDDENLQAYRPSILKRVDEDKQTATDITPCDYSTAENKSGKIITPYTKISVHKTEPLEEPQTFEAKNNFAILQAR
SSTEKCKRARARKDGTTRQCYLIEEPLKQAWESEYEITTQLVKAIYERPKQDDQIEPTFYETSELAYSSTRKSEITQNEL
NLNEKFMEFVEVYEGHYLNDIIKESSEYKEWVKNHVRFKEGVCMVLEIEEQPRAKSTPLSIENSRVVCIKKGNYLFNEV
MKKSLCLSFFLTFSNPLQALVIELLEEIKTSPHKGTFKAKVLDSKEPRQVLGVYNISPHKKLTLTITHISTAIVYQPLDE
KLSLETTLNPNRPTIPRNTQIVFSSKELKESHSHQMPSLNAPMQKPQNKPHSSQQPSQNFSYPEPKLGSKNSKNSLLQPL
AIPSKISPTNETQTPTNDTKPPLKHSSEDQENNLFITPPTEKTLPNNTSNTGISENNESNENRDNVEKQAIRDPNVKEFA
CGKWVYDDENLQAYRPSILKRVDEDKQTATDITPCDYSTAENKSGKIITPYTKISVHKTEPLEEPQTFEAKNNFAILQAR
SSTEKCKRARARKDGTTRQCYLIEEPLKQAWESEYEITTQLVKAIYERPKQDDQIEPTFYETSELAYSSTRKSEITQNEL
NLNEKFMEFVEVYEGHYLNDIIKESSEYKEWVKNHVRFKEGVCMVLEIEEQPRAKSTPLSIENSRVVCIKKGNYLFNEV
Nucleotide
Download Length: 1440 bp
>NTDB_id=46840 HPLT_RS07355 WP_000748985.1 1508954..1510393(-) (comH) [Helicobacter pylori Lithuania75]
ATGAAAAAATCCCTTTGTCTGTCTTTCTTTCTGACTTTCTCTAACCCTCTTCAAGCCCTTGTGATCGAGCTTTTAGAAGA
AATTAAAACTTCACCGCATAAAGGCACTTTTAAGGCTAAAGTCCTTGATTCTAAAGAACCAAGACAAGTTTTAGGCGTTT
ATAATATCTCCCCACACAAAAAACTCACGCTCACTATCACCCACATATCCACTGCAATCGTCTATCAACCCCTTGATGAA
AAACTTTCTTTAGAAACGACCTTAAACCCTAACCGCCCTACTATCCCTAGAAACACCCAAATTGTTTTTTCTTCAAAAGA
ATTGAAAGAGTCGCACTCGCACCAAATGCCTTCTTTAAACGCGCCCATGCAAAAACCACAAAACAAGCCCCATTCATCAC
AACAACCTTCTCAAAACTTTTCTTACCCAGAGCCCAAACTAGGCTCTAAAAACTCTAAAAACAGCCTTTTACAGCCTTTA
GCAATTCCTAGCAAAATAAGCCCCACTAACGAAACTCAAACGCCAACAAACGACACTAAACCCCCTTTAAAGCATTCTTC
AGAAGATCAAGAAAACAACCTTTTTATAACGCCACCCACCGAAAAAACACTCCCTAACAACACCTCTAACACTGGTATTA
GTGAAAACAATGAAAGCAACGAAAATAGGGACAATGTGGAAAAACAAGCGATTAGAGATCCCAATGTTAAAGAATTTGCG
TGCGGGAAGTGGGTCTATGACGATGAAAACTTGCAAGCTTACCGCCCAAGCATTTTAAAACGCGTTGATGAAGACAAACA
GACTGCGACAGATATTACCCCTTGCGATTACAGCACCGCTGAAAATAAAAGCGGTAAAATCATTACCCCCTATACTAAAA
TCTCCGTTCATAAAACAGAGCCTTTAGAAGAGCCGCAAACTTTTGAAGCTAAAAACAATTTCGCCATTCTTCAAGCCAGA
AGCTCTACAGAAAAATGCAAAAGGGCTAGAGCGCGAAAAGACGGCACGACTAGGCAATGCTATCTAATAGAAGAGCCTTT
AAAACAAGCGTGGGAAAGTGAGTATGAAATCACCACGCAATTAGTGAAAGCCATTTATGAACGCCCCAAACAAGACGATC
AAATAGAGCCGACTTTTTATGAAACCAGCGAATTGGCTTATTCTTCCACACGAAAAAGCGAAATAACGCAAAACGAATTG
AATTTGAATGAAAAATTCATGGAATTTGTGGAAGTGTATGAAGGGCATTATTTAAACGATATAATCAAAGAAAGCAGTGA
ATACAAAGAATGGGTTAAAAACCATGTGCGCTTTAAAGAAGGAGTGTGCATGGTTTTAGAAATAGAAGAGCAACCACGAG
CTAAAAGCACGCCTTTGAGTATTGAAAACTCTCGTGTGGTGTGTATCAAAAAAGGGAATTATTTATTCAACGAAGTTTGA
ATGAAAAAATCCCTTTGTCTGTCTTTCTTTCTGACTTTCTCTAACCCTCTTCAAGCCCTTGTGATCGAGCTTTTAGAAGA
AATTAAAACTTCACCGCATAAAGGCACTTTTAAGGCTAAAGTCCTTGATTCTAAAGAACCAAGACAAGTTTTAGGCGTTT
ATAATATCTCCCCACACAAAAAACTCACGCTCACTATCACCCACATATCCACTGCAATCGTCTATCAACCCCTTGATGAA
AAACTTTCTTTAGAAACGACCTTAAACCCTAACCGCCCTACTATCCCTAGAAACACCCAAATTGTTTTTTCTTCAAAAGA
ATTGAAAGAGTCGCACTCGCACCAAATGCCTTCTTTAAACGCGCCCATGCAAAAACCACAAAACAAGCCCCATTCATCAC
AACAACCTTCTCAAAACTTTTCTTACCCAGAGCCCAAACTAGGCTCTAAAAACTCTAAAAACAGCCTTTTACAGCCTTTA
GCAATTCCTAGCAAAATAAGCCCCACTAACGAAACTCAAACGCCAACAAACGACACTAAACCCCCTTTAAAGCATTCTTC
AGAAGATCAAGAAAACAACCTTTTTATAACGCCACCCACCGAAAAAACACTCCCTAACAACACCTCTAACACTGGTATTA
GTGAAAACAATGAAAGCAACGAAAATAGGGACAATGTGGAAAAACAAGCGATTAGAGATCCCAATGTTAAAGAATTTGCG
TGCGGGAAGTGGGTCTATGACGATGAAAACTTGCAAGCTTACCGCCCAAGCATTTTAAAACGCGTTGATGAAGACAAACA
GACTGCGACAGATATTACCCCTTGCGATTACAGCACCGCTGAAAATAAAAGCGGTAAAATCATTACCCCCTATACTAAAA
TCTCCGTTCATAAAACAGAGCCTTTAGAAGAGCCGCAAACTTTTGAAGCTAAAAACAATTTCGCCATTCTTCAAGCCAGA
AGCTCTACAGAAAAATGCAAAAGGGCTAGAGCGCGAAAAGACGGCACGACTAGGCAATGCTATCTAATAGAAGAGCCTTT
AAAACAAGCGTGGGAAAGTGAGTATGAAATCACCACGCAATTAGTGAAAGCCATTTATGAACGCCCCAAACAAGACGATC
AAATAGAGCCGACTTTTTATGAAACCAGCGAATTGGCTTATTCTTCCACACGAAAAAGCGAAATAACGCAAAACGAATTG
AATTTGAATGAAAAATTCATGGAATTTGTGGAAGTGTATGAAGGGCATTATTTAAACGATATAATCAAAGAAAGCAGTGA
ATACAAAGAATGGGTTAAAAACCATGTGCGCTTTAAAGAAGGAGTGTGCATGGTTTTAGAAATAGAAGAGCAACCACGAG
CTAAAAGCACGCCTTTGAGTATTGAAAACTCTCGTGTGGTGTGTATCAAAAAAGGGAATTATTTATTCAACGAAGTTTGA
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comH | Helicobacter pylori 26695 |
97.495 |
100 |
0.975 |