Detailed information NTG0468173

Bioinformatically predicted

Overview

• Name: lytF
• Type: Regulator
• Locus tag: I6J38_RS07725
• Genome accession: NZ_CP069558
• Coordinates: 1541435..1543363 (-)
• Length: 642 a.a.
• NCBI ID: WP_020997517.1
• Uniprot ID: U2ZRW2
• Organism: Streptococcus constellatus strain FDAARGOS_1208
• Function: cell lysis (predicted from homology) Cell lysis

Genomic Context

Location: 1536435..1548363

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J38_RS07705 (I6J38_07705)	purM	1537400..1538422 (+)	1023	WP_148290519.1	phosphoribosylformylglycinamidine cyclo-ligase	-
I6J38_RS07710 (I6J38_07710)	purN	1538422..1538976 (+)	555	WP_006268966.1	phosphoribosylglycinamide formyltransferase	-
I6J38_RS07715 (I6J38_07715)	-	1539083..1539790 (+)	708	WP_020999305.1	suppressor of fused domain protein	-
I6J38_RS07720 (I6J38_07720)	purH	1539832..1541379 (+)	1548	WP_020997516.1	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	-
I6J38_RS07725 (I6J38_07725)	lytF	1541435..1543363 (-)	1929	WP_020997517.1	GBS Bsp-like repeat-containing protein	Regulator
I6J38_RS07730 (I6J38_07730)	purD	1543559..1544827 (+)	1269	WP_020997518.1	phosphoribosylamine--glycine ligase	-
I6J38_RS07735 (I6J38_07735)	purE	1545028..1545519 (+)	492	WP_006268920.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
I6J38_RS07740 (I6J38_07740)	purK	1545506..1546597 (+)	1092	WP_006269021.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
I6J38_RS07745 (I6J38_07745)	-	1546597..1547258 (+)	662	Protein_1504	hypothetical protein	-
I6J38_RS07750 (I6J38_07750)	-	1547274..1547501 (+)	228	WP_006269208.1	hypothetical protein	-
I6J38_RS07755 (I6J38_07755)	-	1547506..1548255 (+)	750	WP_022525721.1	hypothetical protein	-

Sequence

Protein

• Length: 642 a.a.
• Molecular weight: 71103.63 Da
• Isoelectric Point: 8.7315

>NTDB_id=468173 I6J38_RS07725 WP_020997517.1 1541435..1543363(-) (lytF) [Streptococcus constellatus strain FDAARGOS_1208]
MKKYSQLFLLSSALLSVFSAQLTVQASEANNASKNSNPTTLASDVTVNVSGNSVSINYIRSQAQNPYTISHAVWSDENGQ
DDLKWYSASQTSTTVDLSQHSGYGTFHVHTYININGKMIGLNGTTFKVEKPANSTVSTVFGKNAQISFTRNKDQTNANIL
HAVWSDEKGQDDIKWYTAGQHKTEIDLSNHRGYGIYHVHTYENKNGKMTGLNGTTFNLEKPNPTIQTSFPEPGIMDIRIK
NVPETIYKLTVPTWSDKNGQDDLQWYAATKNPDGSYNVRVELKKHNYDTGTYHIHLYGESYVKPEFTGLAGTTVQVRSDQ
LPSEEEQKPFFSVENINQEQGTYTVKVSETSKSKPIQSVRVPIWSTSNQSNIKWYAATNNGDGTFTATFDIRNHQVLSGT
YTNHIYVKYKDGSEHSYATDSVTMSAEKIKTKVSVNKRSTYLYEVTVTDAYGDGTITLPTWSEVNGQDDIQWYTATKAGN
GIYKFTVDTQKHTGSGLFHTHVYRNLNGQMIGLAGTSYQVEKPAVSFQPNYAAATTYPKGQCTWGAKALAPWAGNYWGNG
GDWAASARRAGFKTGTTPQVGAIICWTDGSYGHVGVVTHVASNTRIQIQEANYAGKQYIGNFRGWFNPHAAGQGVVSYIY
PK

Nucleotide

• Length: 1929 bp

>NTDB_id=468173 I6J38_RS07725 WP_020997517.1 1541435..1543363(-) (lytF) [Streptococcus constellatus strain FDAARGOS_1208]
ATGAAAAAATATAGTCAATTGTTTTTACTATCCAGCGCCCTTTTGAGTGTTTTTTCAGCTCAACTAACAGTTCAAGCCTC
GGAAGCAAATAATGCTTCAAAAAACTCAAATCCAACAACTCTTGCTAGCGATGTTACTGTCAATGTTTCTGGCAATAGCG
TTTCTATCAACTACATACGTTCACAAGCCCAAAACCCCTACACCATTTCCCATGCTGTTTGGTCTGATGAAAATGGGCAA
GATGACCTTAAATGGTATTCCGCATCTCAAACATCAACAACTGTTGATTTGAGCCAACATTCTGGGTACGGTACTTTCCA
TGTCCATACATATATCAACATCAATGGAAAAATGATCGGTTTAAATGGAACGACTTTCAAAGTGGAAAAACCCGCTAATA
GCACGGTTTCTACAGTTTTTGGAAAGAATGCTCAAATATCCTTCACTCGAAACAAGGATCAAACCAATGCTAATATTTTA
CACGCTGTTTGGTCTGACGAAAAAGGGCAAGATGACATCAAGTGGTATACAGCAGGTCAACATAAGACAGAAATTGACTT
ATCTAATCATAGAGGCTATGGCATTTACCATGTTCATACTTATGAAAATAAAAACGGAAAAATGACTGGTTTAAACGGTA
CCACTTTTAACCTTGAAAAACCAAATCCTACTATTCAAACTAGTTTTCCAGAACCTGGTATTATGGATATTCGGATAAAA
AATGTCCCTGAAACAATCTATAAACTAACTGTTCCAACTTGGTCTGATAAAAACGGACAAGATGATCTTCAATGGTATGC
AGCTACTAAAAATCCTGATGGAAGCTACAATGTTAGAGTTGAGCTAAAAAAACACAACTATGACACAGGAACTTATCACA
TTCATCTTTACGGAGAAAGCTATGTCAAACCAGAGTTTACTGGCTTAGCTGGAACTACGGTACAAGTTCGTTCCGATCAA
TTGCCTTCTGAAGAAGAGCAAAAACCATTCTTCTCTGTTGAAAATATCAATCAAGAACAAGGGACTTATACCGTCAAAGT
TAGTGAAACTTCAAAGTCCAAGCCGATTCAATCCGTCCGAGTACCTATTTGGAGCACGAGCAATCAAAGCAATATCAAGT
GGTATGCAGCCACTAATAACGGTGACGGAACATTTACGGCAACCTTTGATATTCGCAATCATCAAGTTTTGTCCGGAACA
TATACCAATCATATTTATGTGAAATATAAAGACGGTAGCGAGCATAGTTACGCAACGGATTCGGTTACTATGTCCGCAGA
AAAGATTAAAACCAAAGTGTCTGTTAATAAACGCTCAACTTATCTTTATGAGGTGACAGTGACAGATGCCTACGGTGACG
GAACGATTACCCTACCGACTTGGTCTGAAGTCAACGGCCAAGATGATATTCAGTGGTACACCGCTACTAAAGCTGGAAAT
GGAATTTACAAATTCACAGTTGATACGCAAAAACATACTGGCAGCGGGCTTTTCCATACACATGTCTACCGCAATCTCAA
CGGTCAAATGATTGGACTAGCAGGTACAAGCTATCAGGTAGAGAAGCCTGCTGTCTCTTTCCAACCAAATTATGCCGCAG
CAACGACTTATCCAAAAGGTCAATGCACTTGGGGCGCCAAAGCTCTTGCGCCTTGGGCTGGCAATTATTGGGGCAACGGT
GGTGACTGGGCTGCTAGTGCCAGACGAGCTGGTTTTAAAACAGGAACAACTCCACAAGTCGGAGCCATTATTTGTTGGAC
AGATGGTAGTTACGGACACGTTGGAGTCGTCACTCACGTGGCCTCAAACACACGCATTCAGATTCAAGAGGCAAACTACG
CTGGGAAACAGTACATTGGCAACTTTCGTGGCTGGTTTAATCCCCATGCAGCTGGGCAAGGAGTAGTCAGTTACATTTAT
CCAAAATAA

Domains

Predicted by InterProScan.

• CHAP domain (CHAP) (535-612)

• GBS Bsp-like repeat (GBS_Bsp-like) (67-125)

• GBS Bsp-like repeat (GBS_Bsp-like) (157-216)

• GBS Bsp-like repeat (GBS_Bsp-like) (333-419)

• GBS Bsp-like repeat (GBS_Bsp-like) (435-517)

• GBS Bsp-like repeat (GBS_Bsp-like) (230-300)

3D structure

• AlphaFold DB: U2ZRW2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
lytF	Streptococcus gordonii strain NCTC7865	45.349	80.374	0.364