Detailed information NTG0468090

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: HS055_RS01870
• Genome accession: NZ_CP059243
• Coordinates: 361340..362665 (+)
• Length: 441 a.a.
• NCBI ID: WP_240020007.1
• Uniprot ID: -
• Organism: Mannheimia haemolytica strain 0002
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 356340..367665

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HS055_RS01845 (HS055_01820)	-	356488..359058 (-)	2571	WP_409042056.1	penicillin-binding protein 1A	-
HS055_RS01850 (HS055_01825)	-	359182..359880 (+)	699	WP_240020005.1	competence protein ComA	-
HS055_RS01855 (HS055_01830)	-	359856..360377 (+)	522	WP_006247934.1	hypothetical protein	-
HS055_RS01860 (HS055_01835)	-	360379..360915 (+)	537	WP_006247935.1	hypothetical protein	-
HS055_RS01865 (HS055_01840)	-	360918..361331 (+)	414	WP_006247936.1	hypothetical protein	-
HS055_RS01870 (HS055_01845)	comE	361340..362665 (+)	1326	WP_240020007.1	type IV pilus secretin PilQ	Machinery gene
HS055_RS01875 (HS055_01850)	nusB	362735..363148 (+)	414	WP_006247938.1	transcription antitermination factor NusB	-
HS055_RS01880 (HS055_01855)	thiL	363204..364190 (+)	987	WP_240021822.1	thiamine-phosphate kinase	-
HS055_RS01885 (HS055_01860)	-	364195..364668 (+)	474	WP_240028074.1	phosphatidylglycerophosphatase A	-
HS055_RS01890 (HS055_01865)	-	364675..365298 (+)	624	WP_006247941.1	LysE family transporter	-
HS055_RS01895 (HS055_01870)	ruvA	365410..366015 (+)	606	WP_006247943.1	Holliday junction branch migration protein RuvA	-
HS055_RS01900 (HS055_01875)	ruvB	366152..367156 (+)	1005	WP_006247944.1	Holliday junction branch migration DNA helicase RuvB	-

Sequence

Protein

• Length: 441 a.a.
• Molecular weight: 48891.06 Da
• Isoelectric Point: 7.1883

>NTDB_id=468090 HS055_RS01870 WP_240020007.1 361340..362665(+) (comE) [Mannheimia haemolytica strain 0002]
MWRIFIYFLCGFSLAYANTISIVLKNAPTSLIFTYLAEETGKNMVLDDNIETKSTLRLENKSVDEIFKTLGKVNKLSLTQ
EDDIVYIHXKEEKAADLTPLPIMNLQNNGQNTPLVTAPKLITKTLKLHYAKASXEVIESLTKGSGTFLSENGYIHFDERS
NSLIVKDSAKSLKNIENLVKQLDQPTEQIAIEARIVTISSEHLQELGVRWGIFSRGAGHYKFGGRLEGNGLNNVTNNLNV
NFPITGGASAVLQVSSINSRVLDLELSALEQENSVEIIASPRLLTTNKKPASIKQGTEIPYVMYNTKSEATDVEFKEAVL
GLEVVPHLSTQNQILLDLIVTQNSPNSQSGSSGLITIDKQELNTQVFAKHGETIVLGGIFQHLTXKGEDKVPILGSIPFI
KRLFSQTRDKISKRELVIFVTPYILQSNEKSSNRKNQNSTS

Nucleotide

• Length: 1326 bp

>NTDB_id=468090 HS055_RS01870 WP_240020007.1 361340..362665(+) (comE) [Mannheimia haemolytica strain 0002]
ATGTGGCGAATTTTTATATATTTCTTATGCGGTTTTTCATTAGCCTATGCGAATACCATTTCCATAGTTTTAAAAAATGC
TCCAACTTCGCTTATTTTTACTTATTTAGCGGAAGAAACCGGTAAAAATATGGTGCTTGATGATAATATTGAAACCAAAT
CAACACTACGATTAGAAAATAAATCGGTTGACGAGATTTTTAAAACGCTTGGCAAAGTCAATAAATTATCCTTAACGCAA
GAAGATGATATTGTTTATATTCACAANAAAGAGGAAAAAGCGGCTGACTTAACGCCTCTGCCAATAATGAATTTGCAAAA
TAATGGGCAAAATACACCGCTTGTCACCGCCCCTAAGTTAATCACAAAAACCTTGAAACTACATTATGCAAAGGCTTCCN
NAGAGGTGATTGAGTCGTTAACCAAAGGCAGCGGAACGTTTTTATCGGAAAACGGTTATATTCACTTTGATGAAAGAAGC
AATAGCCTGATTGTGAAAGACAGTGCAAAATCGCTTAAAAATATCGAGAATTTAGTAAAACAGCTCGACCAACCCACCGA
GCAAATTGCGATTGAGGCTAGAATTGTCACTATCAGTAGCGAGCATTTGCAAGAGCTTGGCGTTCGCTGGGGAATTTTTT
CTCGTGGGGCTGGGCACTATAAATTTGGCGGACGGCTGGAAGGCAATGGACTCAACAATGTCACCAATAACTTAAATGTA
AATTTTCCGATTACTGGTGGAGCATCTGCCGTATTACAGGTTTCGTCCATTAATAGCAGAGTGCTTGATTTAGAATTAAG
TGCATTAGAACAAGAAAATAGTGTGGAAATTATTGCCAGCCCACGCCTGTTAACCACCAATAAAAAGCCGGCAAGTATCA
AGCAAGGCACGGAAATTCCTTATGTGATGTACAACACCAAATCGGAAGCCACCGATGTCGAATTTAAAGAAGCGGTATTA
GGGCTTGAAGTCGTTCCACACCTTTCAACCCAAAATCAAATTCTACTCGATCTGATCGTTACCCAAAATTCGCCAAATTC
CCAATCCGGCAGTAGTGGCTTAATTACGATTGATAAACAAGAGCTAAATACGCAAGTATTTGCCAAACACGGCGAAACCA
TTGTACTTGGTGGTATTTTTCAACATTTAACCCANAAAGGCGAAGATAAAGTGCCGATTTTAGGCTCAATTCCCTTCATC
AAGCGGTTATTTAGTCAAACTCGAGATAAAATCAGCAAAAGAGAGCTAGTCATTTTTGTGACGCCTTATATCCTTCAATC
TAATGAAAAGAGCAGCAACCGCAAAAATCAAAATAGCACATCATAA

Domains

Predicted by InterproScan.

• Bacterial type II and III secretion system protein (Secretin) (268-425)

• Bacterial type II/III secretion system short domain (Secretin_N) (58-188)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Glaesserella parasuis strain SC1401	63.785	97.052	0.619
comE	Haemophilus influenzae Rd KW20	50.337	100	0.508
comE	Haemophilus influenzae 86-028NP	50.229	98.866	0.497
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	38.152	95.692	0.365
pilQ	Vibrio cholerae strain A1552	38.152	95.692	0.365
pilQ	Vibrio campbellii strain DS40M4	37.442	97.506	0.365