Detailed information NTG0468090

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: I6J38_RS00205
• Genome accession: NZ_CP069558
• Coordinates: 39797..40852 (+)
• Length: 351 a.a.
• NCBI ID: WP_020997642.1
• Uniprot ID: U2ZNX3
• Organism: Streptococcus constellatus strain FDAARGOS_1208
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 34797..45852

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J38_RS00175 (I6J38_00175)	-	35317..35952 (-)	636	WP_003035211.1	YigZ family protein	-
I6J38_RS00180 (I6J38_00180)	comFA/cflA	36009..37310 (+)	1302	WP_020997640.1	DEAD/DEAH box helicase	Machinery gene
I6J38_RS00185 (I6J38_00185)	comFC/cflB	37307..37972 (+)	666	WP_006267632.1	ComF family protein	Machinery gene
I6J38_RS00190 (I6J38_00190)	hpf	38051..38593 (+)	543	WP_006267638.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
I6J38_RS00195 (I6J38_00195)	rsmD	38790..39329 (+)	540	WP_037592514.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
I6J38_RS00200 (I6J38_00200)	coaD	39319..39816 (+)	498	WP_006267255.1	pantetheine-phosphate adenylyltransferase	-
I6J38_RS00205 (I6J38_00205)	sepM	39797..40852 (+)	1056	WP_020997642.1	SepM family pheromone-processing serine protease	Regulator
I6J38_RS00210 (I6J38_00210)	-	41139..41696 (+)	558	WP_006267391.1	YutD family protein	-
I6J38_RS00215 (I6J38_00215)	rlmN	41730..42812 (+)	1083	WP_006267478.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
I6J38_RS00220 (I6J38_00220)	-	42805..43323 (+)	519	WP_003070167.1	VanZ family protein	-
I6J38_RS00225 (I6J38_00225)	cclA/cilC	43318..43992 (-)	675	WP_020997643.1	prepilin peptidase	Machinery gene
I6J38_RS00230 (I6J38_00230)	-	44143..44670 (+)	528	WP_006267546.1	Dps family protein	-

Sequence

Protein

• Length: 351 a.a.
• Molecular weight: 38352.39 Da
• Isoelectric Point: 10.2387

>NTDB_id=468090 I6J38_RS00205 WP_020997642.1 39797..40852(+) (sepM) [Streptococcus constellatus strain FDAARGOS_1208]
MEKSRTKFKKWPIVAVVGLLLLFMSFIVPLPYYIEVPGGAADVRQVLRVDNKVDKEKGSYNFVTVGIQHATFAHLVYAWL
TPFTDIYSAKDLTGGTSDKEYMRINQFYMETSQNLAKYQGLKKAGKDISLKYLGVYVLQVTKNSTFKGILNIADTVTGVN
DKTFNSSKDLIDYVGSQKIGSKVKVNYVEDGHKKSAIGKIIKLENGKNGIGISLIDRTEVTSNIPIEFSTAGIGGPSAGL
MFSLAIYTQIADPTLRDGRNIAGTGSIDREGKVGDIGGIDKKVVSAAKNGAEIFFAPNNPVTREVKKSNPKAKTNYETAL
AAAKKIKTKMKIVPVKTLQDAIDYLKSTKKS

Nucleotide

• Length: 1056 bp

>NTDB_id=468090 I6J38_RS00205 WP_020997642.1 39797..40852(+) (sepM) [Streptococcus constellatus strain FDAARGOS_1208]
ATGGAAAAATCACGAACTAAATTTAAAAAATGGCCGATAGTGGCTGTAGTAGGGCTGCTTCTACTGTTCATGTCTTTTAT
AGTTCCTCTGCCTTATTACATTGAGGTGCCAGGTGGTGCAGCAGATGTTCGGCAAGTATTACGTGTAGATAATAAAGTGG
ATAAGGAAAAAGGTTCTTATAACTTTGTCACTGTTGGGATTCAGCATGCAACCTTTGCTCATTTGGTTTATGCTTGGTTG
ACTCCTTTTACAGATATTTATTCGGCGAAAGATCTGACTGGCGGAACTTCTGATAAAGAATATATGCGAATCAATCAATT
TTATATGGAAACATCACAAAACTTAGCCAAATATCAAGGGTTAAAAAAAGCAGGTAAGGATATTAGCTTGAAATATTTGG
GTGTTTATGTGTTGCAAGTTACCAAGAATTCAACCTTTAAAGGGATTCTAAATATTGCAGATACTGTGACAGGCGTGAAT
GATAAGACTTTCAACAGTTCAAAAGATTTGATTGATTATGTAGGCTCACAGAAAATTGGCAGCAAGGTCAAGGTGAACTA
TGTAGAAGACGGTCATAAAAAATCTGCTATAGGTAAAATTATCAAACTTGAAAATGGGAAAAATGGAATTGGTATTAGCT
TAATTGACCGAACAGAAGTCACAAGTAATATACCAATTGAATTTTCAACAGCTGGGATTGGTGGACCAAGTGCGGGTTTG
ATGTTTAGCTTGGCGATTTATACACAGATTGCAGACCCGACATTGAGAGATGGCAGAAATATTGCTGGGACAGGATCGAT
TGACCGTGAAGGAAAAGTTGGTGATATTGGTGGGATTGATAAAAAAGTTGTTTCAGCAGCTAAAAATGGCGCAGAAATTT
TCTTTGCGCCAAATAATCCAGTTACCAGGGAAGTGAAAAAATCCAATCCTAAAGCGAAAACAAATTATGAGACAGCTTTG
GCAGCTGCTAAAAAAATTAAAACTAAAATGAAAATTGTACCTGTCAAGACCTTGCAAGACGCAATTGATTACCTCAAAAG
TACTAAAAAATCTTAA

Domains

Predicted by InterProScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (234-306)

• PDZ domain (PDZ_2) (133-195)

3D structure

• AlphaFold DB: U2ZNX3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	63.372	98.006	0.621