Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HPSA_RS00105 Genome accession   NC_017361
Coordinates   14411..16774 (+) Length   787 a.a.
NCBI ID   WP_000890256.1    Uniprot ID   -
Organism   Helicobacter pylori SouthAfrica7     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 9411..21774
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPSA_RS00075 (HPSA_00050) groES 9425..9781 (-) 357 WP_000671961.1 co-chaperone GroES -
  HPSA_RS00080 (HPSA_00055) dnaG 10072..11751 (+) 1680 WP_000601595.1 DNA primase -
  HPSA_RS00085 (HPSA_00060) - 11748..12800 (+) 1053 WP_000721166.1 MnmA/TRMU family protein -
  HPSA_RS00090 (HPSA_00065) - 12892..13719 (+) 828 WP_001154937.1 DUF5718 family protein -
  HPSA_RS00095 (HPSA_00070) comB2 13865..14146 (+) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  HPSA_RS00100 (HPSA_00075) comB3 14146..14409 (+) 264 WP_000584967.1 hypothetical protein Machinery gene
  HPSA_RS00105 (HPSA_00080) comB4 14411..16774 (+) 2364 WP_000890256.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HPSA_RS00110 (HPSA_00085) - 17075..18415 (+) 1341 WP_014534700.1 COG3014 family protein -
  HPSA_RS00115 (HPSA_00090) cheV1 18510..19475 (+) 966 WP_000785503.1 chemotaxis protein CheV1 -
  HPSA_RS00120 (HPSA_00095) nspC 19472..20689 (+) 1218 WP_000808864.1 carboxynorspermidine decarboxylase -
  HPSA_RS00125 (HPSA_00100) lpxE 20731..21264 (-) 534 WP_234701631.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90218.62 Da        Isoelectric Point: 8.5097

>NTDB_id=46805 HPSA_RS00105 WP_000890256.1 14411..16774(+) (comB4) [Helicobacter pylori SouthAfrica7]
MLEKFLGAIKQKVSNYFLGALPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDYKQSIQSDSQYLQAILNQFENKEVYENRYFLVLESTHSLHGVLEHKKKSFMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLNSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQEGFNQKTYN
RLIGIKAYESERITSIAVGALLYQETPLDIIFSIEPMSVNKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNVLIKAPSLEDLDAQTSLVLGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLVIGATGSGKSTLISYLMMSTLKYQNMRLLAFDRMQGL
YSFTEFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMLDLAPSRDKEALEDMNAISGAIKSLYETLYPKDFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSNAFLNVINLDAITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHNFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLEGLGRYLKIFNSDSSHVNKVKALQKDYPKEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=46805 HPSA_RS00105 WP_000890256.1 14411..16774(+) (comB4) [Helicobacter pylori SouthAfrica7]
ATGCTAGAAAAGTTTTTAGGCGCTATCAAGCAAAAAGTTTCAAATTATTTTTTAGGGGCTTTGCCTAAAAGCTATTCAAT
GAGTGAAGAAAACAATATTTTAGGCTTGTATGATGAGCATTTTTTACTCACTAAAAACGAAAACTTAGTGGGCATCCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACCGAGCGTCAGATGGCGTTGGAT
TCTTTAGAAAAGGTCGTGGCACGCCTGGTGGTTAAAAGGCGTAAAATTGATTATAAACAAAGCATTCAATCTGACTCTCA
ATACTTGCAAGCGATCTTGAACCAGTTTGAAAATAAAGAAGTGTATGAAAATCGGTATTTTTTAGTTTTAGAAAGCACTC
ACTCTTTGCATGGGGTTTTAGAGCATAAGAAAAAATCTTTCATGCACGCTAATAGAGAAAATTTTAAGGATATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCTTAGAAATCCAGCTCAAAAACTATGCCCCCAAACTCTTAAACTC
TAAAGAGGTTTTGAATTTTTATGCAGAATACATTAACGGGTTTGATCTCCCTTTAAAGCCTCTAGTAGGAGGGTATTTGA
GCGATAGCTATATCGCTAGTTCTATCACTTTTGAAAAAGATTACTTCATTCAAGAGGGTTTTAACCAAAAAACCTATAAC
CGCTTGATTGGCATTAAGGCTTATGAGAGCGAACGCATCACTTCTATAGCGGTGGGAGCGCTTTTATACCAAGAGACGCC
TTTGGATATTATCTTTTCCATAGAGCCTATGAGCGTCAATAAAACGCTGAGTTTTTTAAAAGAGAGAGCCAAGTTTAGCA
TGTCCAATCTCGTTAAAAACGAGCTGCTAGAATACCAAGAATTAGTCAAAACCAAACGCCTATCCATGCAAAAATTCGCC
CTAAACGTTCTTATCAAAGCCCCCAGTTTAGAGGATTTAGACGCTCAAACGAGCTTAGTTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCATTTAAACC
ACCGCTTGCGTTTTTTAACCTCTAAAGCCCTAGCGTGTTTAATGGTGTTTGAAAGGCAAAATTTAGGCTTTAAAGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAATAACGCTAAAGAAATTGCTAGAGTGAATGGGCATACTTTAGTTATAGGGGCAACCGGAAGCGGTAAAAGCA
CGCTGATTAGCTATTTAATGATGAGCACTTTGAAATACCAAAACATGCGCCTTTTAGCTTTTGACAGGATGCAAGGGCTG
TATTCTTTTACCGAATTTTTTAAAGGGCATTACCATGACGGCCAATCCTTTAGCATCAACCCCTTTTGTTTAGAGCCTAA
TTTACAGAATTTAGAATTTTTGCAATCCTTTTTTTTGAGCATGTTGGATCTCGCCCCTTCAAGGGATAAAGAAGCCTTGG
AAGATATGAATGCGATTTCTGGCGCGATTAAGAGCCTTTATGAGACCTTATACCCTAAAGATTTTAGTTTGCTAGATTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAACTGGGCTTGAGTTTAGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCGTTCAATTCCAACGCTTTTTTAAATGTGATAAACTTAGATGCGATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTATTTGTTTTATAAGATCTTAGAAGAGTCTAGGAAAAACGACAGCGGGTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTGTTGAACACTAAAATCAACGCTTTAATCACGCAAGCCAGGAAAGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGACATTTACCAACTCAGCGGGGTCAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTTATTTTGTATCCGCAAAAAAACGCTAGGGAATTGAAACACAATTTCAATGTGCCTTTGAGCGAGACTGAAATTTCT
TTTTTAGAAAACACCCCCTTGTATGCCAGGCAGGTTTTAGTCAAAAATTTAGGCAATGGGAGTTCTAACATGATTGATGT
GAGTTTGGAGGGCTTGGGGCGTTATTTGAAAATCTTTAATTCGGATTCTAGTCATGTGAATAAAGTGAAAGCGTTGCAAA
AAGACTACCCTAAAGAGTGGCGTGAAAAACTTTTGAAGAGTTAG

Domains

Predicted by InterproScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

96.569

100

0.966

Multiple sequence alignment