NTDB

Overview

Name	comGA	Type	Machinery gene
Locus tag	SAURSH1000_RS07280	Genome accession	NZ_CP059180
Coordinates	1521852..1522826 (-)	Length	324 a.a.
NCBI ID	WP_000697228.1	Uniprot ID	A0A0D3Q868
Organism	Staphylococcus aureus strain SH1000
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1516852..1527826

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAURSH1000_RS07240 (SAURSH1000_001446)	gcvT	1517353..1518444 (-)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-
SAURSH1000_RS07245 (SAURSH1000_001447)	-	1518603..1519127 (-)	525	WP_001015117.1	shikimate kinase	-
SAURSH1000_RS07250 (SAURSH1000_001448)	-	1519117..1519263 (-)	147	WP_001789879.1	hypothetical protein	-
SAURSH1000_RS07255 (SAURSH1000_001449)	comGF	1519360..1519857 (-)	498	WP_001789864.1	competence type IV pilus minor pilin ComGF	Machinery gene
SAURSH1000_RS07260 (SAURSH1000_001450)	comGE	1519775..1520074 (-)	300	WP_000844413.1	hypothetical protein	Machinery gene
SAURSH1000_RS07265 (SAURSH1000_001451)	comGD	1520061..1520507 (-)	447	WP_001790850.1	competence type IV pilus minor pilin ComGD	Machinery gene
SAURSH1000_RS07270 (SAURSH1000_001452)	comGC	1520485..1520796 (-)	312	WP_000472256.1	competence type IV pilus major pilin ComGC	Machinery gene
SAURSH1000_RS07275 (SAURSH1000_001453)	comGB	1520810..1521880 (-)	1071	Protein_1428	competence type IV pilus assembly protein ComGB	-
SAURSH1000_RS07280 (SAURSH1000_001454)	comGA	1521852..1522826 (-)	975	WP_000697228.1	competence type IV pilus ATPase ComGA	Machinery gene
SAURSH1000_RS07285 (SAURSH1000_001455)	-	1522878..1523501 (-)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
SAURSH1000_RS07290 (SAURSH1000_001456)	-	1523498..1523827 (-)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
SAURSH1000_RS07295 (SAURSH1000_001457)	-	1523827..1524813 (-)	987	WP_000161314.1	ROK family glucokinase	-
SAURSH1000_RS07300 (SAURSH1000_001458)	-	1524810..1525013 (-)	204	WP_000087561.1	YqgQ family protein	-
SAURSH1000_RS07305 (SAURSH1000_001459)	-	1524994..1526457 (-)	1464	WP_001017863.1	rhomboid family intramembrane serine protease	-
SAURSH1000_RS07310 (SAURSH1000_001460)	-	1526469..1527008 (-)	540	WP_000164545.1	5-formyltetrahydrofolate cyclo-ligase	-
SAURSH1000_RS07315 (SAURSH1000_001461)	rpmG	1527217..1527366 (-)	150	WP_001265709.1	50S ribosomal protein L33	-

Sequence

Protein

Download Length: 324 a.a. Molecular weight: 36865.01 Da Isoelectric Point: 9.0399

                                >NTDB_id=467688 SAURSH1000_RS07280 WP_000697228.1 1521852..1522826(-) (comGA) [Staphylococcus aureus strain SH1000]

MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYLF

NKIYFLRISTLPLSLGQESCVIRIVPQFFQPQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN

VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI

LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM

HKYI

Nucleotide

Download Length: 975 bp

                                >NTDB_id=467688 SAURSH1000_RS07280 WP_000697228.1 1521852..1522826(-) (comGA) [Staphylococcus aureus strain SH1000]

TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA

TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT

TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCTTTTC

AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA

ATTTTTTCAACCACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT

TTAGTGGACCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT

GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTCCAAATTAATGTGAATGATAAAGCTGGCATAAA

CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG

CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT

TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC

TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT

CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG

CATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A0D3Q868

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGA	Staphylococcus aureus MW2	99.074	100	0.991
comGA	Staphylococcus aureus N315	99.074	100	0.991

Detailed information NTG0467688