Detailed information NTG0466836

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: HZ322_RS11010
• Genome accession: NZ_CP059049
• Coordinates: 2281272..2282300 (-)
• Length: 342 a.a.
• NCBI ID: WP_017865178.1
• Uniprot ID: A0AAE4T0V0
• Organism: Lactococcus lactis strain N8
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2276272..2287300

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HZ322_RS10985 (HZ322_10990)	-	2276559..2277056 (-)	498	WP_003132662.1	nitroreductase family protein	-
HZ322_RS10990 (HZ322_10995)	-	2277043..2277252 (-)	210	WP_003132661.1	hypothetical protein	-
HZ322_RS10995 (HZ322_11000)	-	2277249..2278076 (-)	828	WP_026138971.1	radical SAM protein	-
HZ322_RS12815	-	2278069..2279268 (-)	1200	WP_017865175.1	MFS transporter	-
HZ322_RS12820	-	2279265..2280191 (-)	927	WP_017865176.1	radical SAM protein	-
HZ322_RS11005 (HZ322_11010)	-	2280294..2281151 (-)	858	WP_017865177.1	Rgg/GadR/MutR family transcriptional regulator	-
HZ322_RS11010 (HZ322_11015)	sepM	2281272..2282300 (-)	1029	WP_017865178.1	SepM family pheromone-processing serine protease	Regulator
HZ322_RS11015 (HZ322_11020)	coaD	2282287..2282784 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
HZ322_RS11020 (HZ322_11025)	rsmD	2282832..2283371 (-)	540	WP_050558566.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
HZ322_RS11025 (HZ322_11030)	-	2283542..2284762 (-)	1221	WP_012898647.1	MFS transporter	-
HZ322_RS11030 (HZ322_11035)	lmrP	2284846..2286072 (-)	1227	WP_017865180.1	multidrug efflux MFS transporter LmrP	-
HZ322_RS11035 (HZ322_11040)	-	2286260..2286754 (+)	495	WP_017865181.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37362.96 Da
• Isoelectric Point: 9.9183

>NTDB_id=466836 HZ322_RS11010 WP_017865178.1 2281272..2282300(-) (sepM) [Lactococcus lactis strain N8]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKNIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=466836 HZ322_RS11010 WP_017865178.1 2281272..2282300(-) (sepM) [Lactococcus lactis strain N8]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAAATATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

• PDZ domain (PDZ_2) (134-194)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.986	100	0.494