Detailed information NTG0466801

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: HZ322_RS02830
• Genome accession: NZ_CP059049
• Coordinates: 551333..553783 (+)
• Length: 816 a.a.
• NCBI ID: WP_017864215.1
• Uniprot ID: A0AAE4NT58
• Organism: Lactococcus lactis strain N8
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 546333..558783

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HZ322_RS02805 (HZ322_02805)	-	547097..547609 (+)	513	WP_012897343.1	adenine phosphoribosyltransferase	-
HZ322_RS02810 (HZ322_02810)	rpoE	547826..548389 (+)	564	WP_017864213.1	DNA-directed RNA polymerase subunit delta	-
HZ322_RS02815 (HZ322_02815)	mltG	548526..550178 (+)	1653	WP_017864214.1	endolytic transglycosylase MltG	-
HZ322_RS02820 (HZ322_02820)	greA	550238..550711 (+)	474	WP_025016857.1	transcription elongation factor GreA	-
HZ322_RS02825 (HZ322_02825)	-	550888..551343 (+)	456	WP_010905471.1	CtsR family transcriptional regulator	-
HZ322_RS02830 (HZ322_02830)	clpC	551333..553783 (+)	2451	WP_017864215.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
HZ322_RS02835 (HZ322_02835)	hpf	553918..554475 (+)	558	WP_003129564.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
HZ322_RS02840 (HZ322_02840)	eno	554660..555961 (+)	1302	WP_010905473.1	surface-displayed alpha-enolase	-
HZ322_RS02845 (HZ322_02845)	-	556076..556747 (-)	672	WP_017864216.1	ABC transporter ATP-binding protein	-
HZ322_RS02850 (HZ322_02850)	-	556750..557823 (-)	1074	WP_017864217.1	ABC transporter permease	-
HZ322_RS02855 (HZ322_02855)	-	557835..558404 (-)	570	WP_017864218.1	TetR/AcrR family transcriptional regulator	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90416.81 Da
• Isoelectric Point: 6.4806

>NTDB_id=466801 HZ322_RS02830 WP_017864215.1 551333..553783(+) (clpC) [Lactococcus lactis strain N8]
MKFENIKYTPTLDRILEKAEEYAQQYQYGTIESAHLLAAMATTSGSIAYSLLAGMNVDSSDLLIDLEDLSSHVKVKRSTL
RFSPRAEEVMTAASFLAIHNNSEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKELEKRTGLKVPESKKAVTPMSK
RKMAKGVAENSTTPTLDSVSSDLTEEARLGKLDPMIGREAEIDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSSDPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVKFTDQAIKSAVMLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQQTKRLDLEKELAEAQEELSEAVIKLDIKASRTKEKAVEKIADKIYKFSVKEDKRQEV
TDQAVVAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMKSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAVKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
VSIGASNKKIKIAQIV

Nucleotide

• Length: 2451 bp

>NTDB_id=466801 HZ322_RS02830 WP_017864215.1 551333..553783(+) (clpC) [Lactococcus lactis strain N8]
ATGAAATTTGAAAATATAAAATATACACCAACGCTTGACCGAATTTTAGAAAAAGCGGAAGAGTATGCTCAACAATATCA
ATATGGCACCATTGAAAGTGCTCATTTACTAGCTGCAATGGCAACGACCTCAGGCTCAATTGCTTACAGCCTTCTTGCAG
GAATGAATGTTGATTCTTCTGACTTACTGATTGATTTAGAGGATTTATCAAGTCATGTTAAGGTCAAACGTTCAACTTTA
CGTTTTTCACCTCGTGCAGAGGAAGTGATGACTGCGGCAAGTTTTTTAGCAATTCATAATAACTCAGAAGCCGTTGGAAC
AGAACACTTGCTTTATGCCCTACTTCAAGTAGAAGATGGATTTGGTCTTCAACTTCTGAAATTACAAAAAATCAATATTG
TATCTTTGCGAAAAGAGCTTGAGAAAAGAACTGGACTCAAAGTTCCAGAAAGTAAAAAAGCTGTGACTCCAATGTCAAAA
CGTAAGATGGCAAAGGGAGTTGCAGAAAATTCAACGACGCCAACGTTAGACTCTGTATCCTCAGATTTAACCGAAGAAGC
TCGCTTGGGTAAACTTGACCCAATGATTGGACGAGAAGCTGAAATTGACCGTTTGATTCATATTCTCAGCCGCAGAACAA
AAAATAATCCTGTCTTAGTTGGAGAGCCCGGTGTTGGGAAATCAGCAATTATTGAAGGTTTGGCTCAAAGAATTGTCAAT
GGTCAAGTTCCAATTGGTTTGATGAATAGTCGAATTATGGCCTTGAATATGGCGACTGTTGTTGCTGGGACAAAATTTAG
AGGTGAATTTGAGGATCGTTTGACAGCTATTGTTGAAGAAGTTAGCAGTGATCCAGATGTCATTATTTTCATTGATGAAT
TACACACAATCATCGGTGCTGGTGGCGGTATGGATTCTGTCAATGATGCCGCAAATATTTTGAAACCAGCGCTTGCTCGT
GGTGATTTTCAAATGGTCGGAGCAACAACCTATCATGAATATCAAAAATATATTGAAAAAGATGAAGCTTTAGAACGCCG
TTTGGCGAGAATAAATGTTGATGAGCCAAGTCCAGATGAAGCGATTGCTATTTTGCAAGGCTTACGTGAAAAATTTGAAG
ACTATCATCAAGTGAAATTTACTGACCAAGCCATTAAAAGTGCTGTAATGCTCAGTGTTCGTTATATGACTAGCCGAAAA
TTGCCTGACAAAGCCATTGATTTACTTGATGAAGCTGCAGCAGCAGTGAAAATTTCTGTCAAAAATCAACAAACAAAACG
TCTTGATTTAGAAAAAGAATTAGCGGAAGCTCAAGAAGAATTATCAGAAGCTGTCATTAAACTTGATATCAAAGCGTCTC
GTACAAAAGAAAAAGCAGTTGAAAAAATTGCTGACAAGATTTATAAATTCTCAGTAAAAGAAGATAAACGTCAAGAAGTT
ACTGACCAAGCTGTTGTTGCTGTTGCCTCAACACTGACAGGTGTTCCAATCACACAAATGACTAAGTCTGAAAGTGATCG
TTTAATCAATCTTGAAAAAGAATTACACAAACGAGTTGTTGGACAAGAAGAAGCTATTTCTGCCGTTTCAAGAGCCATTC
GTCGGGCACGTTCCGGTGTTGCTGACAGCCGTCGTCCAATGGGTTCTTTCATGTTCCTTGGACCAACAGGGGTCGGTAAA
ACCGAACTTGCTAAAGCACTGGCTGACAGTGTGTTTGGTAGTGAAGATAATATGATTCGTGTTGACATGAGTGAATTCAT
GGAAAAACATTCGACTTCACGCTTGATTGGAGCTCCTCCAGGGTATGTAGGTTATGATGAGGGTGGTCAATTGACAGAAC
GCGTTCGTAATAAACCTTATTCTGTTGTTCTTTTAGATGAAGTCGAAAAAGCTCATCCTGACGTTTTCAACATCATGTTG
CAAATTCTAGATGATGGCTTTGTGACTGATACTAAAGGTCGTAAAGTTGATTTCAGAAATACAATTATTATCATGACTTC
AAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACAGTTGGTTTTGGCGCTAAAAATATCACAGCTGATTATTCAGCCA
TGAAATCAAGAATATTAGAAGAGCTTAAACGTCATTATCGTCCTGAGTTTCTTAATCGAATTGATGAAAATATTGTTTTC
CACTCATTGGAAAGTCAAGAGATTGAACAAATTGTTAAAATTATGAGTAAATCTTTGATTAAACGTCTGGCAGAACAAGA
TATTCATGTTAAACTCACACCGTCAGCGGTGAAATTAATTGCTGAGGTAGGTTTTGACCCAGAATATGGTGCACGTCCGC
TCCGCAAGGCTCTTCAAAAAGAAGTTGAAGACCTTTTAAGTGAACAATTGCTCTCTGGTGAAATCAAAGCAGGTAATCAT
GTTTCAATTGGGGCATCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-802)

• AAA lid domain (AAA_lid_9) (357-453)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-334)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-144)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	99.877	100	0.999
clpC	Streptococcus thermophilus LMD-9	50.542	100	0.515
clpC	Streptococcus thermophilus LMG 18311	50.421	100	0.513
clpC	Streptococcus pneumoniae Rx1	48.798	100	0.498
clpC	Streptococcus pneumoniae D39	48.798	100	0.498
clpC	Bacillus subtilis subsp. subtilis str. 168	50.499	98.284	0.496
clpC	Streptococcus pneumoniae TIGR4	48.678	100	0.496
clpC	Streptococcus mutans UA159	48.558	100	0.495
clpE	Streptococcus mutans UA159	47.846	79.657	0.381
clpC	Lactococcus lactis subsp. cremoris KW2	47.023	80.27	0.377
clpE	Streptococcus pneumoniae TIGR4	47.687	76.838	0.366
clpE	Streptococcus pneumoniae Rx1	47.687	76.838	0.366
clpE	Streptococcus pneumoniae D39	47.687	76.838	0.366
clpE	Streptococcus pneumoniae R6	47.687	76.838	0.366