Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   SLUG_RS05025 Genome accession   NC_017353
Coordinates   1075204..1075920 (-) Length   238 a.a.
NCBI ID   WP_014533282.1    Uniprot ID   -
Organism   Staphylococcus lugdunensis N920143     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1070204..1080920
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SLUG_RS05005 (SLUG_10170) - 1070259..1071503 (+) 1245 WP_002477917.1 ammonium transporter -
  SLUG_RS05010 (SLUG_10180) - 1071603..1072553 (+) 951 WP_002461422.1 LacI family DNA-binding transcriptional regulator -
  SLUG_RS05015 (SLUG_10190) - 1072653..1074137 (+) 1485 WP_002477918.1 sucrose-6-phosphate hydrolase -
  SLUG_RS05020 (SLUG_10200) - 1074138..1075112 (+) 975 WP_002477919.1 carbohydrate kinase family protein -
  SLUG_RS05025 (SLUG_10210) agrA 1075204..1075920 (-) 717 WP_014533282.1 quorum-sensing response regulator AgrA Regulator
  SLUG_RS05030 (SLUG_10220) agrC 1075933..1077222 (-) 1290 WP_002477920.1 quorum-sensing sensor histidine kinase AgrC -
  SLUG_RS05035 (SLUG_10230) agrD 1077244..1077387 (-) 144 WP_002477921.1 cyclic lactone autoinducer peptide AgrD -
  SLUG_RS05040 (SLUG_10240) - 1077390..1077956 (-) 567 WP_002477922.1 accessory gene regulator AgrB -
  SLUG_RS05045 (SLUG_10250) - 1078584..1079369 (-) 786 WP_002477923.1 carbon-nitrogen family hydrolase -
  SLUG_RS05050 (SLUG_10260) - 1079504..1080127 (-) 624 WP_002461413.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27961.96 Da        Isoelectric Point: 5.6814

>NTDB_id=46675 SLUG_RS05025 WP_014533282.1 1075204..1075920(-) (agrA) [Staphylococcus lugdunensis N920143]
MKIYICEDDVKQRENMVEIINNYIMIEEKPMEIALATDNPYEILKMSKENEDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPAELKTRIIDCLETAHTRLKLLSKERTVETIELKRGSNSVYVQYDEVM
FFESSTNSHRLIAYLDNRQIEFYGNLKQISQIDDRFFRCHNSFVVNRHNISSINSKERVVYFKNGEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=46675 SLUG_RS05025 WP_014533282.1 1075204..1075920(-) (agrA) [Staphylococcus lugdunensis N920143]
ATGAAGATTTACATTTGTGAAGATGATGTTAAACAACGTGAAAATATGGTTGAGATCATCAATAACTATATCATGATTGA
AGAAAAACCAATGGAAATTGCTTTAGCTACAGATAATCCTTATGAAATTTTAAAAATGTCAAAGGAAAATGAGGATGTTG
GTTGTTATTTTTTAGATATTCAATTAGAAGCTGACATAAACGGTATCAAGTTAGGTAGCGAAATAAGAAAGTATGATCCG
ATAGGTAACATAATTTTTGTTACAAGTCATAGTGAGCTGACATATTTAACTTTTGTTTACAAAGTATCGGCTATGGATTT
TATTTTTAAAGATGACCCTGCCGAACTTAAAACTCGTATTATCGATTGCCTTGAAACCGCACATACGCGCTTAAAGTTAT
TGTCAAAAGAACGTACCGTTGAAACGATAGAGCTTAAGCGCGGTAGTAATTCTGTATATGTGCAATATGATGAAGTGATG
TTTTTTGAATCATCAACAAATTCACATCGATTGATTGCATATTTAGATAATCGTCAAATTGAGTTTTATGGTAATCTAAA
ACAAATTAGTCAAATCGATGATCGTTTCTTTAGATGCCATAATAGTTTTGTTGTCAATCGACACAATATCTCTTCAATCA
ATTCAAAAGAACGTGTTGTATATTTTAAAAATGGTGAACATTGTTATGCATCAGTACGCAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

86.134

100

0.861

Multiple sequence alignment