Detailed information NTG0046666

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MS7_RS14160
• Genome accession: NC_017351
• Coordinates: 2744872..2745759 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus subsp. aureus 11819-97
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2739872..2750759

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MS7_RS14125	-	2739890..2739982 (+)	93	WP_010956583.1	hypothetical protein	-
MS7_RS14130 (MS7_2626)	-	2740090..2740587 (-)	498	WP_001065268.1	glutathione peroxidase	-
MS7_RS14135	-	2740597..2740857 (-)	261	WP_001791974.1	hypothetical protein	-
MS7_RS14140	-	2741239..2741352 (-)	114	Protein_2678	hypothetical protein	-
MS7_RS14150 (MS7_2627)	-	2742011..2744011 (-)	2001	WP_000776751.1	ABC transporter permease	-
MS7_RS14155 (MS7_2628)	-	2744008..2744763 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
MS7_RS14160 (MS7_2629)	braS	2744872..2745759 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MS7_RS14165 (MS7_2630)	braR	2745770..2746435 (-)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MS7_RS14170 (MS7_2631)	-	2746461..2746661 (-)	201	WP_000604727.1	hypothetical protein	-
MS7_RS14180 (MS7_2632)	-	2746859..2748283 (+)	1425	WP_000953757.1	alkaline phosphatase	-
MS7_RS15540	-	2748353..2748463 (+)	111	WP_001791296.1	hypothetical protein	-
MS7_RS14185 (MS7_2633)	-	2748566..2749021 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MS7_RS14190 (MS7_2634)	-	2749266..2750027 (-)	762	WP_000323447.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=46666 MS7_RS14160 WP_000143420.1 2744872..2745759(-) (braS) [Staphylococcus aureus subsp. aureus 11819-97]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=46666 MS7_RS14160 WP_000143420.1 2744872..2745759(-) (braS) [Staphylococcus aureus subsp. aureus 11819-97]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993