Detailed information NTG0046620

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SARLGA251_RS13310
• Genome accession: NC_017349
• Coordinates: 2648491..2649378 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus subsp. aureus LGA251
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2643491..2654378

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SARLGA251_RS13275	-	2643494..2643586 (+)	93	WP_010956583.1	hypothetical protein	-
SARLGA251_RS13280 (SARLGA251_23930)	-	2643694..2644191 (-)	498	WP_001065267.1	glutathione peroxidase	-
SARLGA251_RS13285	-	2644201..2644461 (-)	261	WP_014532715.1	hypothetical protein	-
SARLGA251_RS13290	-	2644843..2644956 (-)	114	WP_072357681.1	hypothetical protein	-
SARLGA251_RS13300 (SARLGA251_23940)	-	2645631..2647631 (-)	2001	WP_000776732.1	ABC transporter permease	-
SARLGA251_RS13305 (SARLGA251_23950)	-	2647628..2648383 (-)	756	WP_000923772.1	ABC transporter ATP-binding protein	-
SARLGA251_RS13310 (SARLGA251_23960)	braS	2648491..2649378 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SARLGA251_RS13315 (SARLGA251_23970)	braR	2649389..2650054 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SARLGA251_RS13320 (SARLGA251_23980)	-	2650080..2650280 (-)	201	WP_000604727.1	hypothetical protein	-
SARLGA251_RS13330 (SARLGA251_23990)	-	2650478..2651902 (+)	1425	WP_000948997.1	alkaline phosphatase	-
SARLGA251_RS14805	-	2651962..2652063 (-)	102	WP_000731972.1	SE2200 family small protein	-
SARLGA251_RS13335 (SARLGA251_24000)	-	2652185..2652640 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SARLGA251_RS13340 (SARLGA251_24010)	-	2652885..2653646 (-)	762	WP_000323443.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=46620 SARLGA251_RS13310 WP_000143420.1 2648491..2649378(-) (braS) [Staphylococcus aureus subsp. aureus LGA251]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=46620 SARLGA251_RS13310 WP_000143420.1 2648491..2649378(-) (braS) [Staphylococcus aureus subsp. aureus LGA251]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993