Detailed information NTG0046620

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SAI1T1_RS08500
• Genome accession: NC_020529
• Coordinates: 1749552..1750826 (+)
• Length: 424 a.a.
• NCBI ID: WP_001279338.1
• Uniprot ID: A0A0H2XGV4
• Organism: Staphylococcus aureus subsp. aureus ST228
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1744552..1755826

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAI1T1_RS14715	-	1745876..1745971 (+)	96	WP_031761395.1	hypothetical protein	-
SAI1T1_RS08485 (SAI1T1_2012620)	-	1745932..1747062 (-)	1131	WP_000721699.1	HAD family hydrolase	-
SAI1T1_RS08490 (SAI1T1_2012630)	nagE	1747169..1748635 (-)	1467	WP_000276367.1	N-acetylglucosamine-specific PTS transporter subunit IIBC	-
SAI1T1_RS08495 (SAI1T1_2012640)	-	1748763..1749380 (-)	618	WP_000287588.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
SAI1T1_RS08500 (SAI1T1_2012650)	htrA	1749552..1750826 (+)	1275	WP_001279338.1	trypsin-like peptidase domain-containing protein	Regulator
SAI1T1_RS08505 (SAI1T1_2012660)	tyrS	1750920..1752182 (-)	1263	WP_000186029.1	tyrosine--tRNA ligase	-
SAI1T1_RS08510 (SAI1T1_2012670)	-	1752564..1753469 (+)	906	WP_000184370.1	transglycosylase domain-containing protein	-
SAI1T1_RS14720	-	1753449..1753541 (-)	93	WP_031761401.1	hypothetical protein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 45802.98 Da
• Isoelectric Point: 9.9696

>NTDB_id=46620 SAI1T1_RS08500 WP_001279338.1 1749552..1750826(+) (htrA) [Staphylococcus aureus subsp. aureus ST228]
MSDFNHTDHSTTNHSQTPRYRRPKFPWFKTVIVALIAGIIGALLVLGIGKVLNSTILNKDGSTVQTTNNKGGNQLDGQSK
KFGTVHEMIKSVSPTIVGVINMQKASSVDDLLKGKSSKPSEAGVGSGVIYQINNNSAYIVTNNHVIDGANEIRVQLHNKK
QVKAKLVGKDAVTDIAVLKIENTKGIKAIQFANSSKVQTGDSVFAMGNPLGLQFANSVTSGIISASERTIDAETTGGNTK
VSVLQTDAAINPGNSGGALVDINGNLVGINSMKIAATQVEGIGFAIPSNEVKVTIEQLVKHGKIDRPSIGIGLINLKDIP
EEEREQLHTDREDGIYVAKADSDIDLKKGDIITEIDGKKIKDDVDLRSYLYENKKPGESVTVTVIRDGKTKEVKVKLKQQ
KEQPKRQSRSERQSPGQGDRDFFR

Nucleotide

• Length: 1275 bp

>NTDB_id=46620 SAI1T1_RS08500 WP_001279338.1 1749552..1750826(+) (htrA) [Staphylococcus aureus subsp. aureus ST228]
ATGTCAGATTTTAATCATACAGATCATTCTACAACAAACCATAGCCAAACACCTAGATACAGAAGACCTAAATTTCCATG
GTTTAAAACAGTCATCGTTGCATTGATTGCTGGAATTATTGGTGCACTTCTAGTACTTGGTATAGGCAAAGTATTAAATA
GTACAATTTTAAATAAAGATGGTTCAACTGTTCAGACAACAAATAATAAAGGTGGCAATCAATTAGACGGTCAAAGCAAG
AAATTCGGTACCGTTCATGAAATGATAAAATCTGTCTCCCCTACAATTGTTGGAGTTATTAACATGCAAAAAGCATCAAG
TGTAGACGACTTATTAAAAGGCAAATCATCTAAACCATCTGAAGCTGGAGTAGGTTCAGGTGTTATCTATCAAATAAACA
ACAATTCAGCTTATATCGTTACAAACAATCATGTTATTGATGGCGCAAATGAAATTAGAGTCCAATTACATAATAAAAAA
CAAGTTAAAGCGAAATTAGTTGGTAAAGATGCAGTAACTGATATTGCTGTACTTAAAATTGAAAATACAAAAGGTATTAA
AGCGATTCAATTTGCCAACTCTTCAAAAGTACAAACTGGCGATAGCGTATTCGCAATGGGTAACCCATTAGGATTACAAT
TTGCTAACTCTGTAACATCTGGTATCATTTCAGCAAGCGAACGTACGATTGACGCTGAGACAACTGGTGGCAATACAAAA
GTTAGCGTTCTTCAAACAGATGCTGCTATTAACCCAGGTAACTCAGGTGGCGCATTAGTAGATATTAATGGTAATTTAGT
TGGTATTAACTCAATGAAAATTGCTGCGACACAAGTTGAAGGTATCGGGTTTGCTATTCCAAGTAATGAAGTTAAAGTAA
CAATTGAACAACTTGTAAAACATGGTAAAATTGACCGCCCTTCGATTGGTATTGGTTTAATTAATTTGAAAGATATTCCT
GAAGAAGAGCGCGAGCAACTTCATACTGATAGAGAAGACGGTATTTATGTCGCCAAAGCTGATAGTGATATTGATCTTAA
AAAAGGTGATATTATTACAGAAATTGATGGCAAGAAAATTAAAGATGATGTTGATTTAAGAAGCTATTTATATGAAAATA
AAAAACCTGGTGAATCAGTCACTGTTACCGTTATCCGTGATGGTAAAACAAAAGAAGTTAAAGTGAAATTAAAACAACAA
AAAGAACAACCAAAACGTCAAAGCCGATCAGAACGTCAATCACCTGGCCAAGGCGATAGAGATTTCTTTAGATAA

Domains

Predicted by InterProScan.

• Trypsin-like peptidase domain (Trypsin_2) (125-269)

• PDZ domain (PDZ_2) (307-397)

3D structure

• AlphaFold DB: A0A0H2XGV4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	39.055	94.811	0.37