Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   SARLGA251_RS10135 Genome accession   NC_017349
Coordinates   2044090..2044806 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus subsp. aureus LGA251     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2039090..2049806
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SARLGA251_RS10105 (SARLGA251_18350) - 2039307..2039933 (+) 627 WP_000522384.1 nitroreductase family protein -
  SARLGA251_RS10110 (SARLGA251_18360) - 2040295..2041080 (+) 786 WP_000867945.1 carbon-nitrogen family hydrolase -
  SARLGA251_RS10115 hld 2041678..2041758 (-) 81 WP_000046022.1 delta-hemolysin -
  SARLGA251_RS10120 (SARLGA251_18380) - 2042049..2042612 (+) 564 WP_001105699.1 accessory gene regulator AgrB -
  SARLGA251_RS10125 (SARLGA251_18390) agrD 2042615..2042758 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  SARLGA251_RS10130 (SARLGA251_18400) agrC 2042788..2044071 (+) 1284 WP_000447882.1 quorum-sensing sensor histidine kinase AgrC -
  SARLGA251_RS10135 (SARLGA251_18410) agrA 2044090..2044806 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  SARLGA251_RS10140 - 2044878..2044985 (+) 108 WP_001803734.1 hypothetical protein -
  SARLGA251_RS10145 (SARLGA251_18420) - 2045173..2046132 (-) 960 WP_001253303.1 carbohydrate kinase family protein -
  SARLGA251_RS10150 (SARLGA251_18430) - 2046129..2047613 (-) 1485 WP_000141420.1 sucrose-6-phosphate hydrolase -
  SARLGA251_RS10155 (SARLGA251_18440) - 2047762..2048712 (-) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=46616 SARLGA251_RS10135 WP_000688492.1 2044090..2044806(+) (agrA) [Staphylococcus aureus subsp. aureus LGA251]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=46616 SARLGA251_RS10135 WP_000688492.1 2044090..2044806(+) (agrA) [Staphylococcus aureus subsp. aureus LGA251]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAACATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment