Detailed information NTG0046572

Bioinformatically predicted

Overview

• Name: agrA
• Type: Regulator
• Locus tag: SAT0131_RS10885
• Genome accession: NC_017347
• Coordinates: 2144670..2145386 (+)
• Length: 238 a.a.
• NCBI ID: WP_000688492.1
• Uniprot ID: A0A7U7IEW1
• Organism: Staphylococcus aureus subsp. aureus T0131
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	2142633..2143805	2144670..2145386	flank	865

Gene organization within MGE regions

Location: 2142633..2145386

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAT0131_RS10875 (SAT0131_02187)	-	2142633..2143805 (+)	1173	WP_000195430.1	IS256-like element IS256 family transposase	-
SAT0131_RS10880 (SAT0131_02188)	-	2143902..2144651 (+)	750	Protein_2081	GHKL domain-containing protein	-
SAT0131_RS10885 (SAT0131_02189)	agrA	2144670..2145386 (+)	717	WP_000688492.1	LytTR family DNA-binding domain-containing protein	Regulator

Sequence

Protein

• Length: 238 a.a.
• Molecular weight: 27905.90 Da
• Isoelectric Point: 6.0927

>NTDB_id=46572 SAT0131_RS10885 WP_000688492.1 2144670..2145386(+) (agrA) [Staphylococcus aureus subsp. aureus T0131]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide

• Length: 717 bp

>NTDB_id=46572 SAT0131_RS10885 WP_000688492.1 2144670..2145386(+) (agrA) [Staphylococcus aureus subsp. aureus T0131]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-120)

• LytTr DNA-binding domain (LytTR) (151-237)

3D structure

• AlphaFold DB: A0A7U7IEW1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
agrA	Staphylococcus aureus N315	100	100	1