Detailed information
Bioinformatically predicted
Overview
| Name | sxy/tfoX | Type | Regulator |
| Locus tag | HZT12_RS14925 | Genome accession | NZ_CP058796 |
| Coordinates | 2992043..2992672 (-) | Length | 209 a.a. |
| NCBI ID | WP_000839153.1 | Uniprot ID | A0A9Q6Y251 |
| Organism | Shigella flexneri strain STLIN_8 | ||
| Function | positive regulator of competence gene (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 2982871..3020395 | 2992043..2992672 | within | 0 |
Gene organization within MGE regions
Location: 2982871..3020395
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HZT12_RS14875 (HZT12_14760) | tusE | 2983142..2983471 (+) | 330 | WP_000904442.1 | sulfurtransferase TusE | - |
| HZT12_RS14880 (HZT12_14765) | yccX | 2983468..2983746 (-) | 279 | WP_000048252.1 | acylphosphatase | - |
| HZT12_RS14885 (HZT12_14770) | rlmI | 2983841..2985031 (+) | 1191 | WP_000116297.1 | 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI | - |
| HZT12_RS14890 (HZT12_14775) | hspQ | 2985089..2985406 (+) | 318 | WP_001295356.1 | heat shock protein HspQ | - |
| HZT12_RS14895 (HZT12_14780) | - | 2985451..2985864 (-) | 414 | WP_000665217.1 | CoA-binding protein | - |
| HZT12_RS14900 (HZT12_14785) | - | 2986037..2986699 (+) | 663 | WP_000847785.1 | DUF2057 family protein | - |
| HZT12_RS14905 (HZT12_14790) | mgsA | 2986795..2987253 (+) | 459 | WP_000424181.1 | methylglyoxal synthase | - |
| HZT12_RS14910 (HZT12_14795) | helD | 2987285..2989339 (-) | 2055 | WP_240765526.1 | DNA helicase IV | - |
| HZT12_RS14915 (HZT12_14800) | - | 2989462..2989908 (+) | 447 | WP_001261235.1 | YccF domain-containing protein | - |
| HZT12_RS14920 (HZT12_14805) | yccS | 2989918..2992080 (+) | 2163 | WP_000875061.1 | YccS family putative transporter | - |
| HZT12_RS14925 (HZT12_14810) | sxy/tfoX | 2992043..2992672 (-) | 630 | WP_000839153.1 | CRP-S regulon transcriptional coactivator Sxy | Regulator |
| HZT12_RS14930 (HZT12_14815) | sulA | 2992891..2993400 (+) | 510 | WP_000288710.1 | SOS-induced cell division inhibitor SulA | - |
| HZT12_RS14935 (HZT12_14820) | ompA | 2993757..2994797 (+) | 1041 | WP_000750416.1 | porin OmpA | - |
| HZT12_RS14940 (HZT12_14825) | matP | 2994873..2995325 (-) | 453 | WP_000877161.1 | macrodomain Ter protein MatP | - |
| HZT12_RS14945 (HZT12_14830) | - | 2995511..2997271 (+) | 1761 | WP_000156518.1 | Lon protease family protein | - |
| HZT12_RS14950 (HZT12_14835) | fabA | 2997340..2997858 (+) | 519 | WP_000227927.1 | bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase | - |
| HZT12_RS14955 (HZT12_14840) | rmf | 2997928..2998095 (-) | 168 | WP_000828648.1 | ribosome modulation factor | - |
| HZT12_RS14960 (HZT12_14845) | pqiC | 2998351..2998914 (-) | 564 | WP_032173938.1 | membrane integrity-associated transporter subunit PqiC | - |
| HZT12_RS14965 (HZT12_14850) | pqiB | 2998911..3000551 (-) | 1641 | WP_000445533.1 | intermembrane transport protein PqiB | - |
| HZT12_RS14970 (HZT12_14855) | pqiA | 3000556..3001809 (-) | 1254 | WP_000333176.1 | membrane integrity-associated transporter subunit PqiA | - |
| HZT12_RS14975 (HZT12_14860) | - | 3001939..3003846 (-) | 1908 | WP_000053099.1 | ABC transporter ATP-binding protein | - |
| HZT12_RS14980 (HZT12_14865) | rlmKL | 3003858..3005966 (-) | 2109 | WP_001086539.1 | bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL | - |
| HZT12_RS14985 (HZT12_14870) | ycbX | 3006210..3007319 (+) | 1110 | WP_000212426.1 | 6-N-hydroxylaminopurine resistance protein YcbX | - |
| HZT12_RS14990 (HZT12_14875) | zapC | 3007316..3007858 (-) | 543 | WP_001295353.1 | cell division protein ZapC | - |
| HZT12_RS14995 (HZT12_14880) | pyrD | 3008032..3009042 (-) | 1011 | WP_001295352.1 | quinone-dependent dihydroorotate dehydrogenase | - |
| HZT12_RS15000 (HZT12_14885) | - | 3009153..3009890 (-) | 738 | WP_001111465.1 | fimbrial chaperone | - |
| HZT12_RS15005 (HZT12_14890) | - | 3009856..3010371 (-) | 516 | WP_000919497.1 | fimbrial protein | - |
| HZT12_RS15010 (HZT12_14895) | - | 3010379..3010921 (-) | 543 | WP_000730614.1 | fimbrial protein | - |
| HZT12_RS15015 (HZT12_14900) | - | 3010933..3012003 (-) | 1071 | WP_016242025.1 | fimbrial protein | - |
| HZT12_RS15020 (HZT12_14905) | - | 3011994..3014594 (-) | 2601 | WP_016242024.1 | fimbrial biogenesis usher protein | - |
| HZT12_RS15025 (HZT12_14910) | - | 3014619..3015320 (-) | 702 | WP_016242023.1 | molecular chaperone | - |
| HZT12_RS15030 (HZT12_14915) | - | 3015403..3015666 (-) | 264 | Protein_2952 | fimbrial protein | - |
| HZT12_RS15035 (HZT12_14920) | - | 3015729..3016880 (+) | 1152 | WP_001254932.1 | IS30-like element IS30 family transposase | - |
| HZT12_RS15040 (HZT12_14925) | - | 3016887..3017165 (-) | 279 | Protein_2954 | fimbrial protein | - |
| HZT12_RS15045 (HZT12_14930) | ssuE | 3017521..3018096 (+) | 576 | WP_001263933.1 | NADPH-dependent FMN reductase | - |
| HZT12_RS15050 (HZT12_14935) | ssuA | 3018089..3019048 (+) | 960 | WP_001244342.1 | aliphatic sulfonate ABC transporter substrate-binding protein SsuA | - |
| HZT12_RS15055 (HZT12_14940) | ssuD | 3019045..3020190 (+) | 1146 | WP_000056006.1 | FMNH2-dependent alkanesulfonate monooxygenase | - |
Sequence
Protein
Download Length: 209 a.a. Molecular weight: 24147.02 Da Isoelectric Point: 9.2180
>NTDB_id=465475 HZT12_RS14925 WP_000839153.1 2992043..2992672(-) (sxy/tfoX) [Shigella flexneri strain STLIN_8]
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLN
YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLN
YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE
Nucleotide
Download Length: 630 bp
>NTDB_id=465475 HZT12_RS14925 WP_000839153.1 2992043..2992672(-) (sxy/tfoX) [Shigella flexneri strain STLIN_8]
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAATCACAAGAATACCTGGCAACGTTGGGCACAATTGAATACCGATCATT
GTTTGGCAGTTACAGCCTGACCGTTGACGACACGGTGTTTGCGATGGTTTCTGATGGTGAGTTGTATCTTCGGGCTTGTG
AGCAAAGTGCACAGTACTGTGTAAAACATCCGCCTGTCTGGCTGACATATAAAAAGTGTGGCCGATCCGTTACCCTCAAT
TACTATCGGGTTGATGAAAGTCTATGGCGAAATCAACTGAAGCTGGTGCGTCTGTCGAAATATTCTCTCGATGCAGCGCT
GAAAGAGAAAAGCACGCGCAATACCCGGGAAAGACTGAAAGATTTGCCCAATATGTCTTTTCATCTGGAAGCGATTCTCG
GGGAGGTGGGGATTAAGGATGTACGGGCGTTACGTATACTTGGGGCAAAAATGTGTTGGTTGCGACTGCGGCAGCAAAAC
AGTCTGGTGACAGAAAAGATTCTGTTTATGCTTGAAGGTGCCATTATCGGCATTCATGAAGCTGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCAGAATGGGCTGACTCTCTTACGCCGAAACAGGAGTTTCCTGCGGAACTTGAGTAA
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAATCACAAGAATACCTGGCAACGTTGGGCACAATTGAATACCGATCATT
GTTTGGCAGTTACAGCCTGACCGTTGACGACACGGTGTTTGCGATGGTTTCTGATGGTGAGTTGTATCTTCGGGCTTGTG
AGCAAAGTGCACAGTACTGTGTAAAACATCCGCCTGTCTGGCTGACATATAAAAAGTGTGGCCGATCCGTTACCCTCAAT
TACTATCGGGTTGATGAAAGTCTATGGCGAAATCAACTGAAGCTGGTGCGTCTGTCGAAATATTCTCTCGATGCAGCGCT
GAAAGAGAAAAGCACGCGCAATACCCGGGAAAGACTGAAAGATTTGCCCAATATGTCTTTTCATCTGGAAGCGATTCTCG
GGGAGGTGGGGATTAAGGATGTACGGGCGTTACGTATACTTGGGGCAAAAATGTGTTGGTTGCGACTGCGGCAGCAAAAC
AGTCTGGTGACAGAAAAGATTCTGTTTATGCTTGAAGGTGCCATTATCGGCATTCATGAAGCTGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCAGAATGGGCTGACTCTCTTACGCCGAAACAGGAGTTTCCTGCGGAACTTGAGTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| sxy/tfoX | Escherichia coli BW25113 strain K-12 |
100 |
100 |
1 |