Detailed information NTG0046533

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ECTR2_RS13270
• Genome accession: NC_017343
• Coordinates: 2627784..2628671 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus subsp. aureus ECT-R
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2622784..2633671

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ECTR2_RS13235	-	2622803..2622895 (+)	93	WP_010956583.1	hypothetical protein	-
ECTR2_RS13240 (ECTR2_2475)	-	2623003..2623500 (-)	498	WP_001065268.1	glutathione peroxidase	-
ECTR2_RS13245	-	2623510..2623770 (-)	261	WP_001791974.1	hypothetical protein	-
ECTR2_RS13250	-	2624152..2624265 (-)	114	Protein_2524	hypothetical protein	-
ECTR2_RS13260 (ECTR2_2476)	-	2624924..2626924 (-)	2001	WP_000776751.1	ABC transporter permease	-
ECTR2_RS13265 (ECTR2_2477)	-	2626921..2627676 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ECTR2_RS13270 (ECTR2_2478)	braS	2627784..2628671 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ECTR2_RS13275 (ECTR2_2479)	braR	2628682..2629347 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ECTR2_RS13280 (ECTR2_2480)	-	2629373..2629573 (-)	201	WP_000604730.1	hypothetical protein	-
ECTR2_RS13290 (ECTR2_2481)	-	2629771..2631195 (+)	1425	WP_000953755.1	alkaline phosphatase	-
ECTR2_RS15170	-	2631255..2631356 (-)	102	WP_000731976.1	SE2200 family small protein	-
ECTR2_RS13295 (ECTR2_2482)	-	2631478..2631933 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ECTR2_RS13300 (ECTR2_2483)	-	2632178..2632939 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=46533 ECTR2_RS13270 WP_000143425.1 2627784..2628671(-) (braS) [Staphylococcus aureus subsp. aureus ECT-R]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=46533 ECTR2_RS13270 WP_000143425.1 2627784..2628671(-) (braS) [Staphylococcus aureus subsp. aureus ECT-R]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1