Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ECTR2_RS10070 Genome accession   NC_017343
Coordinates   2010989..2011705 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus subsp. aureus ECT-R     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2005989..2016705
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ECTR2_RS10040 (ECTR2_1884) - 2006206..2006832 (+) 627 WP_000522381.1 nitroreductase family protein -
  ECTR2_RS10045 (ECTR2_1885) - 2007193..2007978 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  ECTR2_RS15150 hld 2008578..2008658 (-) 81 WP_000046022.1 delta-hemolysin -
  ECTR2_RS10055 (ECTR2_1887) - 2008948..2009511 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  ECTR2_RS10060 (ECTR2_1888) agrD 2009514..2009657 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  ECTR2_RS10065 (ECTR2_1889) agrC 2009687..2010970 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  ECTR2_RS10070 (ECTR2_1890) agrA 2010989..2011705 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ECTR2_RS10075 - 2011777..2011886 (+) 110 Protein_1915 hypothetical protein -
  ECTR2_RS10080 (ECTR2_1891) - 2012074..2013033 (-) 960 WP_001253312.1 carbohydrate kinase family protein -
  ECTR2_RS10085 (ECTR2_1892) - 2013030..2014514 (-) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  ECTR2_RS10090 (ECTR2_1893) - 2014663..2015613 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=46529 ECTR2_RS10070 WP_000688492.1 2010989..2011705(+) (agrA) [Staphylococcus aureus subsp. aureus ECT-R]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=46529 ECTR2_RS10070 WP_000688492.1 2010989..2011705(+) (agrA) [Staphylococcus aureus subsp. aureus ECT-R]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment