Detailed information NTG0465264

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SSU10_RS07680
• Genome accession: NZ_CP058742
• Coordinates: 1542336..1543385 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain 10
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1537336..1548385

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSU10_RS07660 (SSU10_01539)	nadE	1537742..1538566 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
SSU10_RS07665 (SSU10_01540)	-	1539862..1540389 (-)	528	WP_012027591.1	VanZ family protein	-
SSU10_RS07670 (SSU10_01541)	rlmN	1540386..1541498 (-)	1113	WP_074413233.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
SSU10_RS07675 (SSU10_01542)	-	1541507..1542148 (-)	642	WP_012027595.1	YutD-like domain-containing protein	-
SSU10_RS07680 (SSU10_01543)	sepM	1542336..1543385 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
SSU10_RS07685 (SSU10_01544)	coaD	1543372..1543860 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
SSU10_RS07690 (SSU10_01545)	rsmD	1543850..1544389 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SSU10_RS07695 (SSU10_01546)	-	1544697..1545419 (-)	723	WP_012027598.1	lipoprotein	-
SSU10_RS07700 (SSU10_01547)	-	1545476..1545862 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
SSU10_RS07705 (SSU10_01548)	-	1545862..1546080 (-)	219	WP_004194736.1	YqgQ family protein	-
SSU10_RS07710 (SSU10_01549)	-	1546388..1546990 (-)	603	WP_012027601.1	response regulator transcription factor	-
SSU10_RS07715 (SSU10_01550)	-	1546987..1548081 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=465264 SSU10_RS07680 WP_012775295.1 1542336..1543385(-) (sepM) [Streptococcus suis strain 10]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=465264 SSU10_RS07680 WP_012775295.1 1542336..1543385(-) (sepM) [Streptococcus suis strain 10]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605