Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   SSU1300283_RS07135 Genome accession   NZ_CP058741
Coordinates   1439603..1441831 (+) Length   742 a.a.
NCBI ID   WP_002938706.1    Uniprot ID   A0AB37G1C7
Organism   Streptococcus suis strain 13-00283-02     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1437705..1444620 1439603..1441831 within 0


Gene organization within MGE regions


Location: 1437705..1444620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSU1300283_RS07125 (SSU1300283_01441) - 1437705..1438994 (+) 1290 WP_014636745.1 IS4-like element ISSsu2 family transposase -
  SSU1300283_RS07130 (SSU1300283_01442) - 1439149..1439379 (-) 231 WP_002938704.1 DUF1797 family protein -
  SSU1300283_RS07135 (SSU1300283_01443) clpE 1439603..1441831 (+) 2229 WP_002938706.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  SSU1300283_RS07140 (SSU1300283_01444) - 1442017..1442478 (+) 462 WP_002938708.1 NUDIX hydrolase -
  SSU1300283_RS07145 (SSU1300283_01445) - 1442533..1442841 (+) 309 WP_014636826.1 DUF1827 family protein -
  SSU1300283_RS07150 (SSU1300283_01446) - 1443418..1444620 (+) 1203 WP_002935295.1 IS110-like element ISSsu7 family transposase -

Sequence

Protein


Download         Length: 742 a.a.        Molecular weight: 82668.08 Da        Isoelectric Point: 5.3518

>NTDB_id=465200 SSU1300283_RS07135 WP_002938706.1 1439603..1441831(+) (clpE) [Streptococcus suis strain 13-00283-02]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGEHNGRGGQTPPPQQPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVNLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIKLFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVE
KAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFTPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSHNGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLEHPAE
KDLRAVMSSKGTIQIKAQTKTK

Nucleotide


Download         Length: 2229 bp        

>NTDB_id=465200 SSU1300283_RS07135 WP_002938706.1 1439603..1441831(+) (clpE) [Streptococcus suis strain 13-00283-02]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAGCAGCAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTAATAATGCCATCCTACGTGGGTTGGGAGATTTAACAAATC
CTAACAACATGGATCCCTTTAGTGAATTTTTCAATCACCTAGGTGGCTATCCTGGCAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCTACTCAAGCCGGTGAGCATAATGGACGTGGTGGACAGACCCCTCCTCCGCAACAACCCCAACAACC
AAATGGGCTCCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGGGATATTGATCCAGTAATCGGTCGCG
ATCAAGAAATTACCCGTGTCATCGAAATTCTCAACCGTCGTACAAAAAACAACCCTGTTCTTATCGGTGAGCCTGGTGTA
GGTAAAACAGCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTCGATGGCGATGTCCCACAGAAATTACGAGACAAGGAAGT
CATTCGTCTGGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGTGGACAATTTGAAGAACGCATGCAAAAACTCATGG
AAGAAATCCGTAATCGTCGCGAAATCATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGCTCTGCAGGCGAT
GGTAACATGGATGCAGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAACTAGTCGGTGCAACAACGCTCAA
CGAGTACCGTATTATCGAAAAAGATGCCGCCCTAGAACGCCGTATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCGAAG
AAACCATTACCATTCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCTGCTATCGAA
GCTGCCGCAGTACTGTCCAACCGCTACATTCAAGACCGTTTCCTACCAGACAAAGCTATTGACCTTCTGGATGAAGCTGG
TTCAAAAATGAATTTAACCCTCAACTTTATTGATCCAAAGGAAATTGACCAACGCCTGATTGATGCCGAAAATCGGAAAG
CACAAGCTACACGGGATGAGGACTATGAAAAAGCGGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAG
GCAACTATCAGCGAGGAAGATATTCCACTCATTACTGAAAAAGAAATTGAGGCCATCGTTGAGCAAAAAACAAATATCCC
AGTTGGTGATTTAAAAGAAAAGGAACAGTCCCAGCTTGTGAACCTCGCTAGTGACTTAAAAGCCCATGTTATCGGACAAG
ATGAAGCAGTTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCCATTGGATCC
TTCCTCTTTGTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAACAATTAGCTATCAAACTCTTCGGTTCGGCAGA
CAGCATGATCCGCTTCGACATGTCCGAATACATGGAAAAACACGCTGTCGCTAAACTCGTCGGAGCTCCTCCAGGCTATG
TAGGCTATGAGGAGGCTGGACAATTGACAGAAAAAGTCCGTCGTAATCCTTACTCACTCATCCTCCTTGACGAAGTTGAA
AAAGCCCACCCAGATGTCATGCACATGTTCCTTCAGGTCTTAGACGATGGTCGTCTGACAGATGGACAAGGTCGGACAGT
CAGCTTCAAAGATACTATTATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTGCGG
CTATGGAAGGGCGGACTCAATCAGTCCTTGGCCAACTTAGCAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGT
ATTATTGAGTTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACGCCT
TTCTCACAATGGCATCAGCCTCCATGTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACGATCCAAAGATGG
GAGCTCGTCCACTGCGCAGAACCATCCAAGATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCAGAA
AAAGACCTACGTGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(476-639)

AAA lid domain (AAA_lid_9)

(291-389)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(647-721)

ATPase family associated with various cellular activities (AAA) (AAA)

(153-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

82.095

100

0.834
  clpE Streptococcus pneumoniae D39

82.095

100

0.834
  clpE Streptococcus pneumoniae R6

82.095

100

0.834
  clpE Streptococcus pneumoniae TIGR4

82.095

100

0.834
  clpE Streptococcus mutans UA159

82.109

100

0.829
  clpC Lactococcus lactis subsp. cremoris KW2

77.379

97.709

0.756
  clpC Bacillus subtilis subsp. subtilis str. 168

52.462

87.601

0.46
  clpC Streptococcus mutans UA159

48.558

84.097

0.408
  clpC Streptococcus thermophilus LMD-9

48.248

84.636

0.408
  clpC Streptococcus thermophilus LMG 18311

47.93

84.636

0.406
  clpC Streptococcus pneumoniae TIGR4

47.84

84.232

0.403
  clpC Streptococcus pneumoniae Rx1

47.84

84.232

0.403
  clpC Streptococcus pneumoniae D39

47.84

84.232

0.403
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.815

84.636

0.396