Detailed information NTG0465160

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SSU16085_RS08000
• Genome accession: NZ_CP058740
• Coordinates: 1655754..1656803 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain 16085/3b
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1650754..1661803

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSU16085_RS07980 (SSU16085_01625)	nadE	1651363..1652187 (+)	825	WP_024413453.1	ammonia-dependent NAD(+) synthetase	-
SSU16085_RS07985 (SSU16085_01626)	-	1653280..1653807 (-)	528	WP_002942846.1	VanZ family protein	-
SSU16085_RS07990 (SSU16085_01627)	rlmN	1653804..1654916 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
SSU16085_RS07995 (SSU16085_01628)	-	1654925..1655566 (-)	642	WP_014638483.1	YutD-like domain-containing protein	-
SSU16085_RS08000 (SSU16085_01629)	sepM	1655754..1656803 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
SSU16085_RS08005 (SSU16085_01630)	coaD	1656790..1657278 (-)	489	WP_015647233.1	pantetheine-phosphate adenylyltransferase	-
SSU16085_RS08010 (SSU16085_01631)	rsmD	1657268..1657807 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SSU16085_RS08015 (SSU16085_01632)	-	1658114..1658836 (-)	723	WP_024417717.1	hypothetical protein	-
SSU16085_RS08020 (SSU16085_01633)	-	1658893..1659279 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
SSU16085_RS08025 (SSU16085_01634)	-	1659279..1659497 (-)	219	WP_004194736.1	YqgQ family protein	-
SSU16085_RS08030 (SSU16085_01635)	-	1659805..1660407 (-)	603	WP_024417718.1	response regulator transcription factor	-
SSU16085_RS08035 (SSU16085_01636)	-	1660404..1661498 (-)	1095	WP_024415248.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=465160 SSU16085_RS08000 WP_012775295.1 1655754..1656803(-) (sepM) [Streptococcus suis strain 16085/3b]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=465160 SSU16085_RS08000 WP_012775295.1 1655754..1656803(-) (sepM) [Streptococcus suis strain 16085/3b]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATTTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605