Detailed information NTG0046513

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: ECTR2_RS07405
• Genome accession: NC_017343
• Coordinates: 1533250..1533561 (-)
• Length: 103 a.a.
• NCBI ID: WP_000472256.1
• Uniprot ID: -
• Organism: Staphylococcus aureus subsp. aureus ECT-R
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1528250..1538561

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ECTR2_RS07370 (ECTR2_1387)	gcvPA	1528752..1530098 (-)	1347	WP_000019691.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-
ECTR2_RS07375 (ECTR2_1388)	gcvT	1530118..1531209 (-)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-
ECTR2_RS07380 (ECTR2_1389)	-	1531368..1531892 (-)	525	WP_001015120.1	shikimate kinase	-
ECTR2_RS07385	-	1531882..1532028 (-)	147	WP_001792109.1	hypothetical protein	-
ECTR2_RS07390 (ECTR2_1390)	comGF	1532125..1532622 (-)	498	WP_001788897.1	competence type IV pilus minor pilin ComGF	Machinery gene
ECTR2_RS07395 (ECTR2_1391)	comGE	1532540..1532839 (-)	300	WP_000844410.1	hypothetical protein	Machinery gene
ECTR2_RS07400 (ECTR2_1392)	comGD	1532826..1533272 (-)	447	WP_001788899.1	competence type IV pilus minor pilin ComGD	Machinery gene
ECTR2_RS07405 (ECTR2_1393)	comGC	1533250..1533561 (-)	312	WP_000472256.1	competence type IV pilus major pilin ComGC	Machinery gene
ECTR2_RS07410 (ECTR2_1394)	comGB	1533575..1534645 (-)	1071	WP_000776422.1	competence type IV pilus assembly protein ComGB	Machinery gene
ECTR2_RS07415 (ECTR2_1395)	comGA	1534617..1535591 (-)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
ECTR2_RS07420 (ECTR2_1396)	-	1535643..1536266 (-)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
ECTR2_RS07425 (ECTR2_1397)	-	1536263..1536592 (-)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
ECTR2_RS07430 (ECTR2_1398)	-	1536592..1537578 (-)	987	WP_000161311.1	ROK family glucokinase	-
ECTR2_RS07435	-	1537575..1537778 (-)	204	WP_000087561.1	YqgQ family protein	-

Sequence

Protein

• Length: 103 a.a.
• Molecular weight: 11315.36 Da
• Isoelectric Point: 8.5268

>NTDB_id=46513 ECTR2_RS07405 WP_000472256.1 1533250..1533561(-) (comGC) [Staphylococcus aureus subsp. aureus ECT-R]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEAQKTCKSGETITISNGEAVAN

Nucleotide

• Length: 312 bp

>NTDB_id=46513 ECTR2_RS07405 WP_000472256.1 1533250..1533561(-) (comGC) [Staphylococcus aureus subsp. aureus ECT-R]
ATGTTTAAATTTCTTAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGCACAAAAGACATGTAAATCAGGAGAGACAATAACAATTAGTAATGGAGAAGCAGTTGCAAATTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (6-30)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Staphylococcus aureus MW2	100	100	1
comGC	Staphylococcus aureus N315	100	100	1
comGC/cglC	Streptococcus pneumoniae TIGR4	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae Rx1	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae D39	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae R6	46.078	99.029	0.456
comGC/cglC	Streptococcus mitis SK321	51.163	83.495	0.427
comGC/cglC	Streptococcus mitis NCTC 12261	51.163	83.495	0.427
comYC	Streptococcus gordonii str. Challis substr. CH1	42.857	95.146	0.408
comYC	Streptococcus suis isolate S10	50	75.728	0.379
comGC	Bacillus subtilis subsp. subtilis str. 168	41.758	88.35	0.369
comGC	Lactococcus lactis subsp. cremoris KW2	46.341	79.612	0.369