Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   HMPREF0772_RS06115 Genome accession   NC_017342
Coordinates   1236567..1237283 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus subsp. aureus TCH60     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1231567..1242283
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0772_RS06100 (HMPREF0772_11157) - 1232654..1233604 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  HMPREF0772_RS06105 (HMPREF0772_11158) - 1233753..1235237 (+) 1485 WP_001791588.1 sucrose-6-phosphate hydrolase -
  HMPREF0772_RS06110 (HMPREF0772_11159) - 1235234..1236193 (+) 960 WP_001253292.1 carbohydrate kinase -
  HMPREF0772_RS06115 (HMPREF0772_11160) agrA 1236567..1237283 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  HMPREF0772_RS06120 (HMPREF0772_11161) agrC 1237302..1238594 (-) 1293 WP_000387805.1 quorum-sensing sensor histidine kinase AgrC -
  HMPREF0772_RS06125 (HMPREF0772_11162) agrD 1238619..1238759 (-) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  HMPREF0772_RS06130 (HMPREF0772_11163) - 1238763..1239326 (-) 564 WP_001105709.1 accessory gene regulator AgrB -
  HMPREF0772_RS15510 hld 1239616..1239696 (+) 81 WP_000046022.1 delta-hemolysin -
  HMPREF0772_RS06140 (HMPREF0772_11164) - 1240298..1241083 (-) 786 WP_000867948.1 carbon-nitrogen family hydrolase -
  HMPREF0772_RS06145 (HMPREF0772_11165) - 1241444..1242070 (-) 627 WP_000522388.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=46461 HMPREF0772_RS06115 WP_000688492.1 1236567..1237283(-) (agrA) [Staphylococcus aureus subsp. aureus TCH60]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=46461 HMPREF0772_RS06115 WP_000688492.1 1236567..1237283(-) (agrA) [Staphylococcus aureus subsp. aureus TCH60]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment