Detailed information NTG0046399

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SA2981_RS09930
• Genome accession: NC_017340
• Coordinates: 1980391..1981434 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus 04-02981
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1975391..1986434

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SA2981_RS09900 (SA2981_1835)	-	1975812..1977068 (-)	1257	WP_001795108.1	aminopeptidase	-
SA2981_RS09905 (SA2981_1836)	-	1977071..1977271 (-)	201	WP_000180460.1	DUF1128 family protein	-
SA2981_RS09910 (SA2981_1837)	-	1977418..1977882 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SA2981_RS09915 (SA2981_1838)	-	1977889..1978164 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SA2981_RS09920 (SA2981_1839)	-	1978442..1979659 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
SA2981_RS09925 (SA2981_1840)	vraR	1979772..1980401 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
SA2981_RS09930 (SA2981_1841)	vraS	1980391..1981434 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SA2981_RS09935 (SA2981_1842)	liaF	1981431..1982132 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SA2981_RS09940 (SA2981_1843)	-	1982147..1982533 (-)	387	WP_001110179.1	hypothetical protein	-
SA2981_RS09945 (SA2981_1844)	map	1982750..1983508 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SA2981_RS09955 (SA2981_1845)	-	1984039..1985025 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
SA2981_RS09960 (SA2981_1846)	-	1985456..1985869 (-)	414	WP_001557448.1	hypothetical protein	-
SA2981_RS09965	-	1985898..1986008 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=46399 SA2981_RS09930 WP_001017131.1 1980391..1981434(-) (vraS) [Staphylococcus aureus 04-02981]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=46399 SA2981_RS09930 WP_001017131.1 1980391..1981434(-) (vraS) [Staphylococcus aureus 04-02981]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1