Detailed information NTG0046361

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SAA6159_RS13480
• Genome accession: NC_017338
• Coordinates: 2716733..2717620 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus subsp. aureus JKD6159
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2711733..2722620

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAA6159_RS13450 (SAA6159_03830)	-	2711752..2711844 (+)	93	WP_044026065.1	hypothetical protein	-
SAA6159_RS13455 (SAA6159_02517)	-	2711952..2712449 (-)	498	WP_001065272.1	glutathione peroxidase	-
SAA6159_RS13460 (SAA6159_03835)	-	2712459..2712719 (-)	261	WP_078055809.1	hypothetical protein	-
SAA6159_RS13465 (SAA6159_03840)	-	2713101..2713214 (-)	114	WP_072468803.1	hypothetical protein	-
SAA6159_RS13470 (SAA6159_02518)	-	2713873..2715873 (-)	2001	WP_000776731.1	ABC transporter permease	-
SAA6159_RS13475 (SAA6159_02519)	-	2715870..2716625 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
SAA6159_RS13480 (SAA6159_02520)	braS	2716733..2717620 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SAA6159_RS13485 (SAA6159_02521)	braR	2717631..2718296 (-)	666	WP_000697884.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SAA6159_RS13490 (SAA6159_02522)	-	2718322..2718522 (-)	201	WP_000604726.1	hypothetical protein	-
SAA6159_RS13495 (SAA6159_02523)	-	2718720..2720144 (+)	1425	WP_000953737.1	alkaline phosphatase	-
SAA6159_RS14130	-	2720204..2720305 (-)	102	WP_000731976.1	SE2200 family small protein	-
SAA6159_RS13505 (SAA6159_02524)	-	2720427..2720882 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SAA6159_RS13510 (SAA6159_02525)	-	2721127..2721888 (-)	762	WP_000323443.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=46361 SAA6159_RS13480 WP_000143420.1 2716733..2717620(-) (braS) [Staphylococcus aureus subsp. aureus JKD6159]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=46361 SAA6159_RS13480 WP_000143420.1 2716733..2717620(-) (braS) [Staphylococcus aureus subsp. aureus JKD6159]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993