Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   SAA6159_RS10400 Genome accession   NC_017338
Coordinates   2102076..2102792 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus subsp. aureus JKD6159     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2097076..2107792
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAA6159_RS10370 (SAA6159_01947) - 2097289..2097915 (+) 627 WP_000522384.1 nitroreductase family protein -
  SAA6159_RS10375 (SAA6159_01948) - 2098278..2099063 (+) 786 WP_000867958.1 carbon-nitrogen family hydrolase -
  SAA6159_RS14105 hld 2099663..2099743 (-) 81 WP_000046022.1 delta-hemolysin -
  SAA6159_RS10385 (SAA6159_01949) - 2100033..2100596 (+) 564 WP_001105706.1 accessory gene regulator AgrB -
  SAA6159_RS10390 (SAA6159_01950) agrD 2100600..2100740 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  SAA6159_RS10395 (SAA6159_01951) agrC 2100765..2102057 (+) 1293 WP_000387806.1 quorum-sensing sensor histidine kinase AgrC -
  SAA6159_RS10400 (SAA6159_01952) agrA 2102076..2102792 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  SAA6159_RS10405 (SAA6159_03520) - 2102864..2102970 (+) 107 Protein_2014 hypothetical protein -
  SAA6159_RS10410 (SAA6159_01953) - 2103158..2104117 (-) 960 WP_001253298.1 carbohydrate kinase -
  SAA6159_RS10415 (SAA6159_01954) - 2104114..2105598 (-) 1485 WP_000141420.1 sucrose-6-phosphate hydrolase -
  SAA6159_RS10420 (SAA6159_01955) - 2105748..2106698 (-) 951 WP_000790328.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=46357 SAA6159_RS10400 WP_000688492.1 2102076..2102792(+) (agrA) [Staphylococcus aureus subsp. aureus JKD6159]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=46357 SAA6159_RS10400 WP_000688492.1 2102076..2102792(+) (agrA) [Staphylococcus aureus subsp. aureus JKD6159]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGCGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAACATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment