Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JNN79_RS13525 Genome accession   NZ_CP068825
Coordinates   2787639..2788295 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain RIVM_C030256     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2782639..2793295
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JNN79_RS13495 (JNN79_13495) yecA 2783890..2784555 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  JNN79_RS13515 (JNN79_13515) pgsA 2785205..2785753 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JNN79_RS13520 (JNN79_13520) uvrC 2785810..2787642 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JNN79_RS13525 (JNN79_13525) letA 2787639..2788295 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JNN79_RS13530 (JNN79_13530) yecU 2788591..2788767 (+) 177 WP_000590347.1 protein YecU -
  JNN79_RS13535 (JNN79_13535) yecF 2788754..2788978 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  JNN79_RS13540 (JNN79_13540) sdiA 2789046..2789768 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  JNN79_RS13545 (JNN79_13545) tcyN 2789998..2790750 (-) 753 WP_001272982.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JNN79_RS13550 (JNN79_13550) tcyL 2790747..2791415 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  JNN79_RS13555 (JNN79_13555) dcyD 2791430..2792416 (-) 987 WP_001128228.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=463471 JNN79_RS13525 WP_000611328.1 2787639..2788295(-) (letA) [Escherichia coli strain RIVM_C030256]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=463471 JNN79_RS13525 WP_000611328.1 2787639..2788295(-) (letA) [Escherichia coli strain RIVM_C030256]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTAGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482