Detailed information NTG0463217

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: HW271_RS03735
• Genome accession: NZ_CP058258
• Coordinates: 757720..759930 (+)
• Length: 736 a.a.
• NCBI ID: WP_178894899.1
• Uniprot ID: A0A7H8Z975
• Organism: Streptococcus sp. oral taxon 061 strain F0704
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 752720..764930

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HW271_RS03705 (HW271_03705)	cvfB	752984..753838 (+)	855	WP_178894894.1	RNA-binding virulence regulatory protein CvfB	-
HW271_RS03710 (HW271_03710)	-	753847..754062 (+)	216	WP_001232087.1	YozE family protein	-
HW271_RS03715 (HW271_03715)	-	754147..755133 (+)	987	WP_178894895.1	PhoH family protein	-
HW271_RS03720 (HW271_03720)	ald	755182..756294 (-)	1113	WP_178894896.1	alanine dehydrogenase	-
HW271_RS03725 (HW271_03725)	-	756460..757029 (+)	570	WP_178894897.1	GNAT family N-acetyltransferase	-
HW271_RS03730 (HW271_03730)	comEA/celA/cilE	757095..757736 (+)	642	WP_178894898.1	helix-hairpin-helix domain-containing protein	Machinery gene
HW271_RS03735 (HW271_03735)	comEC/celB	757720..759930 (+)	2211	WP_178894899.1	ComEC/Rec2 family competence protein	Machinery gene
HW271_RS03740 (HW271_03740)	-	760053..761339 (+)	1287	WP_178894900.1	U32 family peptidase	-
HW271_RS03745 (HW271_03745)	-	761353..761664 (+)	312	WP_178894901.1	CHY zinc finger protein	-
HW271_RS03750 (HW271_03750)	-	761905..762105 (+)	201	WP_001054551.1	F0F1 ATP synthase subunit C	-
HW271_RS03755 (HW271_03755)	atpB	762138..762854 (+)	717	WP_178894902.1	F0F1 ATP synthase subunit A	-
HW271_RS03760 (HW271_03760)	atpF	762873..763367 (+)	495	WP_178894903.1	F0F1 ATP synthase subunit B	-
HW271_RS03765 (HW271_03765)	-	763367..763903 (+)	537	WP_178894904.1	F0F1 ATP synthase subunit delta	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84586.18 Da
• Isoelectric Point: 9.2577

>NTDB_id=463217 HW271_RS03735 WP_178894899.1 757720..759930(+) (comEC/celB) [Streptococcus sp. oral taxon 061 strain F0704]
MSQWINRFPIPKIYLSFLLLWLYYAIFSASVLALLGFVFLLICLFFQFPWKTVVKVLLVCSLFGSWFVFQKWQQEEASQH
LVNTVDTVRILPDTIKVNGDSLTFRGKADGRLFQIYYKLQSEAEKEKFQELSELHEMVVKGKLASPQGASNFAGFDYRNY
LKTQGIYQTLTISEIVELKQTSSWDIGENLSSLRRKSVVWIKRKFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDAFKKLLLRLGLTQEKFKWLAYPLSLVYAGLTGFSASVIRSLLQKLLAQHGFKSLDNFALTILILFLI
MPNFFLTAGGVLSCAYAFILTMTGEEIEGIRGLVRESCIISLGILPILSFYFSEFQPWSILLTFVFSFLFDMVLLPLLSI
LFCLSFIYPITQFNYLFEWLENIIRYISQLSTRPLVFGQPSLWILILLLITLALIYDYRKNLKKISMLVIVAISLFLVTK
HPLENEITVLDMEQGRSIFLRDMTGKTILLDVGEKSERDKKEAWQERISSSNAERSLIPYLKSRGVAKIDQLVLTTSDTK
QLDHVLEISKAFELEEILVSEETLSKREFMDKLKESNLKVRPIKTGEQLFIFGSGLEVITSQNSDKKDSMVLYGKLLNQT
FLVTGNIEEKLLTKSYPKLQADVVITHQETAKKKNNVEVFKNLQPKITVISVGKKKTYKEKYGDSNQELGDSIYKTDQKG
GIRFKGWSTWQIETVR

Nucleotide

• Length: 2211 bp

>NTDB_id=463217 HW271_RS03735 WP_178894899.1 757720..759930(+) (comEC/celB) [Streptococcus sp. oral taxon 061 strain F0704]
ATGTCACAGTGGATTAATCGTTTTCCCATCCCAAAAATCTATCTTAGTTTTCTTTTGCTATGGCTCTACTATGCAATTTT
TTCAGCAAGTGTATTAGCACTTTTGGGATTTGTCTTTTTACTGATCTGCCTGTTTTTTCAATTTCCATGGAAGACTGTAG
TCAAAGTCCTATTGGTTTGCAGCCTATTTGGGAGTTGGTTTGTATTTCAAAAATGGCAGCAAGAAGAAGCGAGTCAACAT
CTAGTCAACACGGTTGATACAGTTCGAATCTTGCCTGATACCATCAAGGTTAATGGTGATAGCTTGACTTTTCGTGGCAA
GGCTGATGGTAGACTCTTTCAGATCTATTATAAACTCCAGTCGGAAGCTGAAAAGGAAAAATTTCAAGAGTTGTCTGAAC
TACATGAAATGGTTGTGAAAGGCAAGCTAGCTAGTCCTCAAGGTGCCAGTAATTTTGCTGGTTTTGATTATCGAAACTAT
CTCAAAACGCAAGGAATTTATCAGACCTTAACTATATCCGAAATTGTTGAGCTAAAGCAAACAAGTAGTTGGGATATCGG
AGAAAATCTATCAAGCTTGAGGAGAAAATCAGTTGTCTGGATAAAAAGGAAATTTCCCGATCCCATGCGCAACTACATGA
CCGGTCTATTATTGGGGCATTTGGACACAGATTTTGAGGAAATGAATGAACTTTATTCCAGCCTAGGGATTATTCATCTT
TTTGCTTTGTCTGGAATGCAGGTAGGCTTTTTCATGGATGCTTTCAAGAAGTTACTTCTGCGTTTGGGTTTGACGCAAGA
GAAGTTCAAATGGTTAGCCTATCCATTGTCATTGGTCTATGCAGGTTTGACAGGATTTTCAGCTTCAGTTATTCGTAGTC
TTCTACAAAAGCTATTGGCTCAGCATGGCTTTAAGTCACTAGATAATTTTGCTTTGACGATTCTTATTCTATTTCTTATC
ATGCCGAACTTTTTCTTAACAGCTGGAGGGGTTCTATCCTGTGCCTATGCTTTTATACTGACCATGACAGGTGAAGAAAT
AGAAGGAATAAGAGGGTTGGTTAGAGAGAGTTGCATTATTTCCTTGGGAATTCTGCCAATTTTATCATTTTATTTTTCAG
AATTTCAACCGTGGTCCATTCTCTTGACATTTGTCTTTTCATTCTTATTTGATATGGTCCTGTTACCGCTCTTATCGATT
CTCTTCTGTCTGTCATTTATATATCCCATCACCCAGTTCAACTATCTCTTTGAATGGCTTGAAAACATCATTCGCTATAT
TTCTCAGCTATCTACGAGGCCTCTTGTTTTCGGTCAGCCGAGTCTTTGGATTTTAATCCTTCTTTTGATTACTTTAGCTC
TCATCTACGATTATCGAAAGAATTTGAAAAAAATATCTATGCTTGTCATAGTTGCTATCTCACTCTTTTTAGTAACCAAA
CATCCACTGGAGAATGAAATCACAGTCCTAGATATGGAACAGGGGAGGAGCATTTTCCTAAGAGACATGACAGGAAAGAC
CATACTACTGGATGTCGGAGAAAAATCTGAACGTGACAAGAAAGAAGCCTGGCAGGAGAGGATTTCCTCTAGCAATGCCG
AACGGAGTTTAATCCCTTATCTAAAAAGTCGAGGAGTTGCAAAGATTGATCAGCTTGTGCTAACGACTAGTGATACTAAG
CAGTTAGATCATGTGTTAGAAATCAGTAAAGCCTTCGAGCTTGAAGAGATTCTAGTAAGTGAAGAAACTTTATCTAAAAG
AGAATTTATGGATAAATTAAAGGAAAGTAACTTGAAAGTACGTCCTATTAAAACAGGAGAGCAGTTGTTTATTTTTGGGA
GTGGTTTGGAAGTAATCACTAGCCAAAATAGCGATAAAAAGGATTCAATGGTCTTGTATGGAAAGCTACTAAATCAAACT
TTTCTAGTCACTGGAAATATAGAGGAGAAGCTCTTAACCAAGTCCTATCCAAAACTCCAAGCAGATGTAGTGATAACTCA
TCAGGAAACAGCTAAGAAAAAGAATAATGTTGAAGTCTTCAAAAACTTACAACCTAAAATTACGGTCATTTCGGTAGGCA
AGAAGAAAACATACAAAGAAAAATATGGAGATAGTAACCAAGAACTTGGGGATTCGATTTACAAAACGGACCAAAAGGGA
GGCATTCGTTTTAAAGGGTGGAGTACTTGGCAAATAGAAACAGTTCGCTGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (27-176)

• Competence protein (Competence) (216-459)

3D structure

• AlphaFold DB: A0A7H8Z975

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	66.846	100	0.677
comEC/celB	Streptococcus mitis SK321	66.622	100	0.675
comEC/celB	Streptococcus pneumoniae Rx1	66.622	100	0.675
comEC/celB	Streptococcus pneumoniae D39	66.622	100	0.675
comEC/celB	Streptococcus pneumoniae R6	66.622	100	0.675
comEC/celB	Streptococcus pneumoniae TIGR4	65.952	100	0.668
comEC	Lactococcus lactis subsp. cremoris KW2	39.247	100	0.397