Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   HW271_RS02625 Genome accession   NZ_CP058258
Coordinates   542447..544696 (-) Length   749 a.a.
NCBI ID   WP_178894752.1    Uniprot ID   -
Organism   Streptococcus sp. oral taxon 061 strain F0704     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 537447..549696
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HW271_RS02600 (HW271_02600) - 538571..539269 (+) 699 WP_178894747.1 GntR family transcriptional regulator -
  HW271_RS02605 (HW271_02605) metK 539506..540696 (+) 1191 WP_178894748.1 methionine adenosyltransferase -
  HW271_RS02610 (HW271_02610) - 540742..541374 (-) 633 WP_178894749.1 GNAT family N-acetyltransferase -
  HW271_RS02615 (HW271_02615) - 541545..541844 (-) 300 WP_178894750.1 DUF1827 family protein -
  HW271_RS02620 (HW271_02620) - 541908..542357 (-) 450 WP_178894751.1 NUDIX hydrolase -
  HW271_RS02625 (HW271_02625) clpE 542447..544696 (-) 2250 WP_178894752.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  HW271_RS02630 (HW271_02630) - 544937..545167 (-) 231 WP_178894753.1 DUF1797 family protein -
  HW271_RS02635 (HW271_02635) - 545373..546056 (+) 684 WP_178894754.1 amino acid ABC transporter permease -
  HW271_RS02640 (HW271_02640) - 546056..546790 (+) 735 WP_178894755.1 amino acid ABC transporter ATP-binding protein -
  HW271_RS02645 (HW271_02645) - 546928..547785 (+) 858 WP_310437578.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -

Sequence

Protein


Download         Length: 749 a.a.        Molecular weight: 83406.57 Da        Isoelectric Point: 5.1112

>NTDB_id=463211 HW271_RS02625 WP_178894752.1 542447..544696(-) (clpE) [Streptococcus sp. oral taxon 061 strain F0704]
MLCQNCKINDSTIHLYTNLNGQQKQIDLCQNCYKIIKTDPNNSLFKGITDLNNRDFDPFGDFFNDLNNFRPSSNNNVPPT
QSGGGYGGNGGYGSQNRGPAQTPPPSQEKGLLDEYGINITEIARRGNVDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPG
VGKTAVVEGLAQKIVDGDVPHKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRERKDVILFIDEIHEIVGAGSAG
DGNMDAGNILKPALSRGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETIIILKGIQKKYEDYHHVHYTDGAI
EAAATLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQ
KTKVTDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLINLADDLKAHVIGQDDAVDKIAKAIRRNRVGLGTPNRPIG
SFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEV
EKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELGNFFSPEFMNRFD
GIIEFKALSKENLLQIVDLMLDDVNKRLSSNNIHLDVTNKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLENPS
EKDLKAVMTSKGKIVIKSKNKTETVESND

Nucleotide


Download         Length: 2250 bp        

>NTDB_id=463211 HW271_RS02625 WP_178894752.1 542447..544696(-) (clpE) [Streptococcus sp. oral taxon 061 strain F0704]
ATGCTCTGTCAAAATTGTAAAATCAATGACTCAACGATCCATCTTTACACTAATCTGAATGGGCAACAAAAGCAAATCGA
TCTTTGCCAAAATTGCTACAAAATTATCAAAACAGATCCTAACAATAGCTTGTTCAAAGGCATTACAGATTTAAACAATC
GTGATTTTGATCCATTTGGAGACTTCTTCAACGACCTGAACAACTTTAGACCTTCTTCTAATAATAATGTTCCTCCAACC
CAGTCAGGTGGCGGTTACGGTGGTAATGGGGGTTATGGTTCTCAAAATCGTGGACCAGCTCAAACACCTCCTCCTAGTCA
AGAAAAAGGACTCTTGGATGAGTATGGTATCAATATTACCGAGATTGCCCGTCGTGGAAATGTCGACCCAGTTATCGGCC
GTGACGAAGAAATCATCCGTGTCATTGAAATCCTCAACCGCAGAACTAAAAACAACCCAGTACTGATTGGGGAGCCTGGT
GTTGGTAAGACAGCAGTTGTCGAAGGCTTAGCACAGAAAATTGTAGACGGTGATGTTCCCCACAAACTTCAAGGGAAAGA
AGTCATCCGCCTAGATGTCGTGAGTCTTGTTCAAGGCACAGGAATTCGTGGACAGTTCGAAGAGCGCATGCAAAAACTCA
TGGAAGAAATCCGTGAGCGCAAAGATGTCATCCTCTTTATCGACGAAATTCACGAAATTGTCGGTGCTGGTTCTGCTGGA
GACGGGAATATGGATGCAGGCAATATCCTCAAACCAGCCCTATCTCGTGGCGAACTTCAGTTAGTGGGTGCTACTACCCT
CAATGAATACCGCATCATCGAAAAAGATGCTGCCCTTGAGCGCCGTATGCAACCTGTCAAAGTTGATGAACCAACTGTGG
AAGAGACCATTATTATTCTTAAAGGTATTCAAAAGAAATACGAAGATTACCACCACGTTCATTATACTGACGGAGCTATC
GAAGCCGCTGCTACTCTTTCTAATCGCTACATCCAAGATCGTTTCTTGCCAGATAAGGCTATTGACCTTTTAGATGAAGC
TGGTTCAAAAATGAACTTAACCTTGAATTTTGTGGATCCAAAGGTTATCGACCAACGCTTAATCGAAGCGGAAAATCTCA
AGGCTCAAGCAACTCGTGACGAAGATTTTGAAAAAGCCGCCTACTTCCGTGATCAGATTGCCAAATATAAGGAAATGCAA
AAGACAAAGGTAACGGATCAGGATACTCCAATCATCAGTGAAAAGACGATTGAACACATCATTGAACAAAAAACTAATAT
TCCAGTTGGCGACCTTAAAGAAAAAGAACAGTCTCAACTGATCAACCTAGCAGATGATCTCAAGGCACATGTTATTGGCC
AAGATGATGCTGTTGATAAGATTGCCAAGGCTATCCGTCGTAACCGTGTTGGTCTCGGTACTCCAAACCGTCCAATCGGT
AGCTTCCTCTTTGTTGGTCCTACTGGCGTCGGTAAGACAGAACTTTCTAAACAACTAGCTATTGAGCTTTTTGGTTCTGC
TGATAGCATGATTCGCTTTGATATGAGCGAATACATGGAAAAACATAGTGTTGCCAAACTCGTCGGTGCCCCTCCAGGAT
ACGTCGGTTATGATGAGGCTGGACAATTGACCGAGAAAGTCCGTCGCAACCCCTACTCACTTATCCTCTTAGATGAGGTC
GAAAAAGCCCATCCGGATGTCATGCATATGTTCCTTCAAGTTTTGGATGATGGGCGTTTAACGGATGGTCAAGGACGAAC
TGTTAGCTTTAAGGATGCCATCATTATCATGACCTCAAATGCAGGTACAGGAAAGGCTGAAGCAAGCGTTGGATTTGGTG
CAGCTAGAGAAGGTCGTACCAACTCTGTCCTTGGAGAATTAGGCAACTTCTTTAGCCCAGAATTCATGAACCGCTTTGAT
GGTATTATCGAATTTAAGGCCCTCAGCAAGGAAAATCTCCTTCAAATCGTTGACCTTATGTTGGATGATGTGAATAAACG
TCTCTCAAGCAATAACATCCATTTAGATGTAACAAATAAGGTTAAAGAAAAACTTGTAGACCTTGGTTACGATCCAAAAA
TGGGAGCTCGTCCACTCCGTCGTACCATCCAAGACTATATCGAAGATGCCATTACAGACTACTACCTTGAAAATCCTAGT
GAAAAAGACCTCAAGGCAGTCATGACAAGTAAAGGTAAAATCGTGATTAAGTCCAAAAATAAAACGGAAACGGTCGAGTC
AAACGACTAG

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(154-274)

AAA domain (Cdc48 subfamily) (AAA_2)

(477-640)

AAA lid domain (AAA_lid_9)

(292-389)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(648-722)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

93.85

99.866

0.937
  clpE Streptococcus pneumoniae D39

93.85

99.866

0.937
  clpE Streptococcus pneumoniae R6

93.85

99.866

0.937
  clpE Streptococcus pneumoniae TIGR4

93.717

99.866

0.936
  clpE Streptococcus mutans UA159

83.578

100

0.836
  clpC Lactococcus lactis subsp. cremoris KW2

76.587

100

0.773
  clpC Bacillus subtilis subsp. subtilis str. 168

50.431

92.924

0.469
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.166

83.712

0.403
  clpC Streptococcus pneumoniae TIGR4

47.293

83.845

0.397
  clpC Streptococcus pneumoniae Rx1

47.293

83.845

0.397
  clpC Streptococcus pneumoniae D39

47.293

83.845

0.397
  clpC Streptococcus thermophilus LMD-9

46.955

83.311

0.391
  clpC Streptococcus thermophilus LMG 18311

46.635

83.311

0.389
  clpC Streptococcus mutans UA159

46.411

83.712

0.389