Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | SATW20_RS00470 | Genome accession | NC_017331 |
| Coordinates | 96591..97937 (-) | Length | 448 a.a. |
| NCBI ID | WP_000816499.1 | Uniprot ID | Q9R3W9 |
| Organism | Staphylococcus aureus subsp. aureus TW20 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 40890..97937 | 96591..97937 | within | 0 |
Gene organization within MGE regions
Location: 40890..97937
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SATW20_RS00165 (SATW20_00330) | ccrC | 40890..42575 (+) | 1686 | WP_000676600.1 | cassette chromosome recombinase CcrC | - |
| SATW20_RS00170 (SATW20_00340) | tnpA | 42623..43108 (+) | 486 | WP_000093392.1 | IS200/IS605 family transposase | - |
| SATW20_RS00175 (SATW20_00350) | - | 43400..43738 (+) | 339 | WP_000175892.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| SATW20_RS00180 (SATW20_00360) | - | 43832..44143 (+) | 312 | WP_001166716.1 | DUF960 family protein | - |
| SATW20_RS00185 (SATW20_00370) | - | 44159..44665 (+) | 507 | WP_000848380.1 | DUF1643 domain-containing protein | - |
| SATW20_RS00190 (SATW20_00380) | - | 44686..45003 (+) | 318 | Protein_35 | JAB domain-containing protein | - |
| SATW20_RS00195 (SATW20_00390) | - | 45122..46207 (+) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| SATW20_RS00200 (SATW20_00400) | - | 46204..48096 (+) | 1893 | WP_014532403.1 | site-specific integrase | - |
| SATW20_RS00205 (SATW20_00410) | - | 48103..48480 (+) | 378 | WP_001041907.1 | DUF6262 family protein | - |
| SATW20_RS00210 (SATW20_00420) | - | 48631..49413 (+) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| SATW20_RS00215 (SATW20_00430) | erm(A) | 49539..50270 (-) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| SATW20_RS17195 | - | 50328..50387 (-) | 60 | WP_010959190.1 | erythromycin resistance leader peptide | - |
| SATW20_RS00220 (SATW20_00440) | - | 50779..51441 (+) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| SATW20_RS15890 | - | 51673..51819 (+) | 147 | Protein_43 | JAB domain-containing protein | - |
| SATW20_RS00225 (SATW20_00450) | - | 51989..52861 (+) | 873 | WP_000373151.1 | HTH domain-containing protein | - |
| SATW20_RS00230 (SATW20_00460) | - | 52918..53208 (+) | 291 | WP_000065262.1 | hypothetical protein | - |
| SATW20_RS00235 (SATW20_00470) | - | 53224..53712 (+) | 489 | WP_000397419.1 | hypothetical protein | - |
| SATW20_RS00240 (SATW20_00480) | - | 53847..54374 (+) | 528 | WP_000717928.1 | hypothetical protein | - |
| SATW20_RS00245 (SATW20_00490) | - | 54437..54853 (+) | 417 | WP_000941331.1 | hypothetical protein | - |
| SATW20_RS00250 (SATW20_00510) | - | 55320..55541 (+) | 222 | WP_001070883.1 | hypothetical protein | - |
| SATW20_RS00255 (SATW20_00520) | - | 55691..56257 (+) | 567 | WP_000759939.1 | PepSY domain-containing protein | - |
| SATW20_RS00260 (SATW20_00530) | - | 56337..58550 (-) | 2214 | Protein_51 | type I restriction endonuclease subunit R | - |
| SATW20_RS00265 (SATW20_00540) | - | 58612..59286 (-) | 675 | WP_001105999.1 | IS6-like element IS257 family transposase | - |
| SATW20_RS00270 (SATW20_00550) | - | 59569..60915 (+) | 1347 | WP_000163428.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| SATW20_RS00275 (SATW20_00560) | merR | 61215..61622 (+) | 408 | WP_000425271.1 | Hg(II)-responsive transcriptional regulator MerR | - |
| SATW20_RS00280 (SATW20_00570) | - | 61639..61992 (+) | 354 | WP_000746201.1 | TlpA disulfide reductase family protein | - |
| SATW20_RS00285 (SATW20_00580) | - | 61989..62669 (+) | 681 | WP_000010352.1 | cytochrome c biogenesis CcdA family protein | - |
| SATW20_RS00290 (SATW20_00590) | merT | 62757..63143 (+) | 387 | WP_001794630.1 | mercuric transport protein MerT | - |
| SATW20_RS00295 (SATW20_00600) | merA | 63201..64844 (+) | 1644 | WP_000193219.1 | mercury(II) reductase | - |
| SATW20_RS00300 (SATW20_00610) | merB | 64926..65576 (+) | 651 | WP_000790333.1 | organomercurial lyase MerB | - |
| SATW20_RS00305 (SATW20_00620) | - | 65771..66286 (-) | 516 | WP_000377078.1 | hypothetical protein | - |
| SATW20_RS00310 (SATW20_00630) | - | 66405..67079 (-) | 675 | WP_001105988.1 | IS6-like element IS257 family transposase | - |
| SATW20_RS17200 (SATW20_00631) | - | 67512..67844 (-) | 333 | WP_001803416.1 | DUF3021 domain-containing protein | - |
| SATW20_RS00320 (SATW20_00640) | - | 67873..68115 (-) | 243 | WP_001803415.1 | LytTR family DNA-binding domain-containing protein | - |
| SATW20_RS00325 (SATW20_00650) | - | 68247..68921 (-) | 675 | WP_001106055.1 | IS6-like element IS257 family transposase | - |
| SATW20_RS00330 (SATW20_00660) | tet(K) | 69118..70497 (+) | 1380 | WP_000492283.1 | tetracycline efflux MFS transporter Tet(K) | - |
| SATW20_RS00335 (SATW20_00670) | mobV | 70686..71927 (+) | 1242 | WP_000122374.1 | MobV family relaxase | - |
| SATW20_RS15900 (SATW20_00680) | - | 72454..73408 (+) | 955 | Protein_67 | replication initiation factor domain-containing protein | - |
| SATW20_RS00350 (SATW20_00690) | - | 73497..74171 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| SATW20_RS15905 | - | 74207..74596 (+) | 390 | WP_020444595.1 | hydroxymethylglutaryl-CoA synthase | - |
| SATW20_RS00360 (SATW20_00720) | - | 75513..76256 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| SATW20_RS00365 (SATW20_00730) | - | 76353..76781 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| SATW20_RS00370 (SATW20_00740) | mecA | 76827..78836 (-) | 2010 | WP_078056052.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| SATW20_RS00375 (SATW20_00750) | mecR1 | 78933..80690 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| SATW20_RS00380 (SATW20_00760) | mecI | 80690..81061 (+) | 372 | Protein_74 | mecA-type methicillin resistance repressor MecI | - |
| SATW20_RS16685 (SATW20_00761) | psm-mec | 81146..81214 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| SATW20_RS00385 (SATW20_00770) | - | 81534..82682 (+) | 1149 | WP_000427807.1 | ROK family transcriptional regulator | - |
| SATW20_RS00395 (SATW20_00780) | cstB | 82796..84130 (-) | 1335 | Protein_77 | persulfide dioxygenase-sulfurtransferase CstB | - |
| SATW20_RS00400 (SATW20_00790) | - | 84162..85226 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| SATW20_RS00405 (SATW20_00800) | cstR | 85362..85622 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| SATW20_RS00410 (SATW20_00810) | - | 85622..86260 (+) | 639 | Protein_80 | sulfite exporter TauE/SafE family protein | - |
| SATW20_RS00415 (SATW20_00820) | - | 86534..87151 (-) | 618 | WP_000562107.1 | CadD family cadmium resistance transporter | - |
| SATW20_RS00420 (SATW20_00830) | - | 87232..89646 (-) | 2415 | WP_000378486.1 | cadmium-translocating P-type ATPase CadA | - |
| SATW20_RS00425 (SATW20_00840) | - | 89639..90004 (-) | 366 | WP_000159127.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| SATW20_RS00430 (SATW20_00850) | - | 90190..90567 (-) | 378 | WP_001041908.1 | DUF6262 family protein | - |
| SATW20_RS00435 (SATW20_00860) | - | 90574..92466 (-) | 1893 | WP_014532403.1 | site-specific integrase | - |
| SATW20_RS00440 (SATW20_00870) | - | 92661..92984 (-) | 324 | WP_000088091.1 | JAB domain-containing protein | - |
| SATW20_RS00445 (SATW20_00880) | - | 92977..93183 (-) | 207 | WP_001077283.1 | hypothetical protein | - |
| SATW20_RS00450 (SATW20_00890) | - | 93185..93706 (-) | 522 | WP_000836008.1 | DUF1643 domain-containing protein | - |
| SATW20_RS00455 (SATW20_00900) | - | 93725..94036 (-) | 312 | WP_000833212.1 | DUF960 family protein | - |
| SATW20_RS00460 (SATW20_00901) | - | 94121..94471 (-) | 351 | WP_000171449.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| SATW20_RS00465 (SATW20_00910) | ccrB | 94942..96570 (-) | 1629 | WP_001186596.1 | cassette chromosome recombinase CcrB | Machinery gene |
| SATW20_RS00470 (SATW20_00920) | ccrA | 96591..97937 (-) | 1347 | WP_000816499.1 | cassette chromosome recombinase CcrA | Machinery gene |
Sequence
Protein
Download Length: 448 a.a. Molecular weight: 52138.19 Da Isoelectric Point: 10.1760
>NTDB_id=46189 SATW20_RS00470 WP_000816499.1 96591..97937(-) (ccrA) [Staphylococcus aureus subsp. aureus TW20]
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA
Nucleotide
Download Length: 1347 bp
>NTDB_id=46189 SATW20_RS00470 WP_000816499.1 96591..97937(-) (ccrA) [Staphylococcus aureus subsp. aureus TW20]
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
78.174 |
100 |
0.783 |
| ccrA | Staphylococcus aureus N315 |
72.383 |
100 |
0.725 |