Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   JNN54_RS21745 Genome accession   NZ_CP068795
Coordinates   4495960..4498782 (+) Length   940 a.a.
NCBI ID   WP_000357740.1    Uniprot ID   Q3YUS6
Organism   Escherichia coli strain RIVM_C011532     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4490960..4503782
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JNN54_RS21720 (JNN54_21720) soxR 4491897..4492361 (-) 465 WP_000412428.1 redox-sensitive transcriptional activator SoxR -
  JNN54_RS21725 (JNN54_21725) soxS 4492447..4492770 (+) 324 WP_000019358.1 superoxide response transcriptional regulator SoxS -
  JNN54_RS21730 (JNN54_21730) pdeC 4492773..4494359 (-) 1587 WP_000019548.1 c-di-GMP phosphodiesterase PdeC -
  JNN54_RS21735 (JNN54_21735) yjcB 4494789..4495070 (+) 282 WP_001295689.1 YjcB family protein -
  JNN54_RS21740 (JNN54_21740) ssb 4495169..4495705 (-) 537 WP_000168305.1 single-stranded DNA-binding protein SSB1 Machinery gene
  JNN54_RS21745 (JNN54_21745) uvrA 4495960..4498782 (+) 2823 WP_000357740.1 excinuclease ABC subunit UvrA Machinery gene
  JNN54_RS21750 (JNN54_21750) yjbR 4498817..4499173 (-) 357 WP_097503529.1 MmcQ/YjbR family DNA-binding protein -
  JNN54_RS21755 (JNN54_21755) yjbQ 4499177..4499593 (-) 417 WP_000270375.1 secondary thiamine-phosphate synthase enzyme YjbQ -
  JNN54_RS21760 (JNN54_21760) aphA 4499704..4500345 (-) 642 Protein_4326 acid phosphatase AphA -
  JNN54_RS21765 (JNN54_21765) - 4500387..4501756 (+) 1370 WP_085947770.1 IS3-like element IS150 family transposase -
  JNN54_RS21770 (JNN54_21770) aphA 4501784..4501864 (-) 81 Protein_4328 acid phosphatase AphA -
  JNN54_RS21775 (JNN54_21775) - 4502266..4502652 (+) 387 WP_001339137.1 hypothetical protein -

Sequence

Protein


Download         Length: 940 a.a.        Molecular weight: 103867.54 Da        Isoelectric Point: 6.6066

>NTDB_id=461125 JNN54_RS21745 WP_000357740.1 4495960..4498782(+) (uvrA) [Escherichia coli strain RIVM_C011532]
MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLAESFETALELSGGTAVVADMDDP
KAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQM
LKSLADHYKFDVEAPWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSAVREELAKF
ISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTL
SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDI
GPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITG
VSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPE
SRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFF
DAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHKLRD
QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPML

Nucleotide


Download         Length: 2823 bp        

>NTDB_id=461125 JNN54_RS21745 WP_000357740.1 4495960..4498782(+) (uvrA) [Escherichia coli strain RIVM_C011532]
ATGGATAAGATCGAAGTTCGGGGCGCCCGCACCCATAATCTCAAAAACATCAACCTCGTTATCCCCCGCGACAAGCTCAT
TGTCGTGACCGGGCTTTCGGGTTCTGGCAAATCCTCGCTCGCTTTCGACACCTTATATGCCGAAGGGCAGCGCCGTTACG
TTGAATCCCTTTCCGCCTACGCGCGGCAGTTTCTGTCACTGATGGAAAAGCCGGACGTCGATCATATTGAGGGGCTTTCT
CCTGCCATCTCAATTGAGCAGAAATCGACGTCTCATAACCCGCGTTCTACGGTGGGGACAATCACCGAAATCCACGACTA
TTTGCGTTTGTTGTTCGCCCGCGTTGGCGAGCCGCGCTGTCCGGACCACGACGTCCCGCTGGCGGCGCAAACCGTCAGCC
AGATGGTGGATAACGTGCTGTCGCAGCCGGAAGGCAAGCGTCTGATGCTACTCGCGCCAATCATTAAAGAGCGCAAAGGC
GAACACACCAAAACGCTGGAGAACCTGGCAAGCCAGGGCTACATCCGTGCTCGTATTGATGGCGAAGTCTGCGATCTTTC
CGATCCGCCAAAACTGGAACTGCAAAAGAAACATACCATTGAAGTGGTGGTTGATCGCTTCAAGGTGCGTGACGATCTTA
CCCAACGTCTTGCCGAGTCATTTGAAACCGCGCTGGAGCTTTCCGGTGGTACCGCGGTAGTGGCGGATATGGACGACCCG
AAAGCGGAAGAGCTGCTGTTCTCCGCCAACTTCGCCTGCCCAATTTGCGGCTACAGTATGCGTGAACTGGAGCCGCGACT
GTTTTCGTTTAACAACCCGGCGGGGGCCTGCCCGACCTGCGACGGCCTTGGCGTACAGCAATATTTCGATCCTGATCGAG
TGATCCAGAATCCGGAACTGTCGCTGGCTGGTGGTGCGATCCGTGGCTGGGATCGCCGCAACTTCTATTATTTCCAGATG
CTGAAATCGCTGGCAGATCACTATAAGTTCGACGTCGAAGCGCCGTGGGGCAGCCTGAGCGCGAACGTGCATAAAGTGGT
GTTGTACGGTTCTGGCAAAGAAAACATTGAATTCAAATACATGAACGATCGTGGCGATACCTCCATTCGTCGTCATCCGT
TCGAAGGCGTGCTGCATAATATGGAGCGCCGCTATAAAGAGACGGAATCCAGCGCGGTACGCGAAGAATTAGCCAAGTTT
ATCAGTAATCGTCCGTGCGCCAGCTGCGAAGGGACGCGTCTGCGTCGGGAAGCGCGCCACGTGTATGTCGAGAATACGCC
GCTGCCTGCTATCTCCGACATGAGCATTGGTCATGCGATGGAATTCTTCAACAATCTCAAACTCGCAGGTCAGCGGGCGA
AGATTGCAGAAAAAATCCTTAAAGAGATCGGCGATCGTCTGAAATTCCTCGTTAACGTCGGCCTGAATTACCTGACGCTT
TCCCGCTCGGCAGAAACGCTTTCTGGCGGTGAAGCACAGCGTATCCGTCTGGCGAGCCAGATTGGTGCGGGCCTGGTTGG
CGTTATGTACGTGCTGGACGAGCCGTCTATCGGCCTGCACCAGCGTGATAACGAGCGCCTGTTGGGTACGCTTATCCATC
TGCGCGATCTCGGTAATACCGTGATTGTGGTGGAGCACGACGAAGACGCAATTCGCGCCGCTGACCATGTGATCGACATT
GGCCCGGGCGCAGGTGTTCACGGCGGTGAAGTGGTCGCAGAAGGTCCGCTGGAAGCGATTATGGCGGTGCCGGAGTCGTT
GACCGGGCAGTACATGAGCGGCAAACGCAAGATTGAAGTGCCGAAGAAACGCGTTCCGGCGAATCCGGAAAAAGTGCTGA
AGCTGACAGGCGCACGCGGCAACAACCTGAAGGACGTGACGCTGACGCTGCCGGTGGGTCTGTTTACCTGCATCACCGGG
GTTTCAGGTTCCGGTAAATCGACGCTGATTAACGACACGCTGTTCCCTATTGCCCAACGCCAGTTGAATGGTGCGACCAT
CGCCGAACCGGCACCGTATCGCGATATTCAGGGGCTGGAGCATTTCGACAAAGTGATCGATATCGACCAAAGCCCAATTG
GTCGTACTCCGCGTTCTAACCCGGCGACCTATACCGGCGTGTTTACACCTGTGCGCGAACTGTTTGCGGGCGTACCGGAA
TCCCGTGCGCGTGGTTATACGCCAGGACGTTTCAGCTTTAACGTCCGTGGCGGACGCTGCGAAGCCTGTCAGGGCGACGG
TGTGATCAAAGTGGAGATGCACTTCCTGCCGGACATTTACGTACCGTGCGACCAGTGTAAAGGTAAACGCTATAACCGTG
AAACGCTGGAAATTAAGTACAAAGGCAAAACCATCCACGAAGTGCTGGATATGACCATCGAAGAGGCGCGTGAGTTCTTT
GATGCCGTACCTGCACTGGCGCGTAAGCTGCAAACGTTGATGGACGTTGGCCTGACGTACATTCGCCTGGGGCAGTCCGC
AACCACCCTTTCTGGTGGTGAAGCCCAGCGCGTGAAGCTGGCGCGTGAGCTGTCAAAACGCGGCACCGGGCAGACACTGT
ATATTCTCGACGAGCCGACCACCGGTTTGCACTTCGCCGATATTCAGCAACTGCTCGACGTGCTGCATAAACTGCGCGAT
CAGGGCAATACCATTGTGGTAATTGAGCACAATCTCGACGTGATTAAAACCGCTGACTGGATTGTCGACCTGGGACCGGA
AGGCGGCAGTGGCGGCGGCGAGATCCTCGTCTCCGGTACGCCAGAAACCGTCGCGGAGTGCGAAGCTTCGCATACGGCGC
GCTTCCTCAAGCCGATGCTGTAA

Domains

Predicted by InterProScan.

UvrA DNA-binding domain (UvrA_DNA-bind)

(290-399)

ABC transporter (ABC_tran)

(806-860)

UvrA interaction domain (UvrA_inter)

(130-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3YUS6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

57.37

100

0.576
  uvrA Streptococcus pneumoniae TIGR4

57.37

100

0.576
  uvrA Streptococcus pneumoniae D39

57.37

100

0.576