Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   DRO_RS08905 Genome accession   NZ_CP068791
Coordinates   1797378..1800428 (-) Length   1016 a.a.
NCBI ID   WP_010888406.1    Uniprot ID   Q46577
Organism   Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539 strain R1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1792378..1805428
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DRO_RS08885 (DRO_1747) trpD 1792881..1793897 (+) 1017 WP_027480347.1 anthranilate phosphoribosyltransferase -
  DRO_RS08890 (DRO_1748) - 1793959..1794477 (-) 519 WP_027480346.1 hypothetical protein -
  DRO_RS08895 (DRO_1749) - 1794611..1796335 (+) 1725 WP_010888404.1 desiccation/radiation resistance protein -
  DRO_RS08900 (DRO_1750) - 1796392..1797135 (-) 744 WP_010888405.1 hypothetical protein -
  DRO_RS08905 (DRO_1751) uvrA 1797378..1800428 (-) 3051 WP_010888406.1 excinuclease ABC subunit UvrA Machinery gene
  DRO_RS08910 (DRO_1752) - 1800631..1800882 (-) 252 WP_162177796.1 hypothetical protein -
  DRO_RS08915 (DRO_1753) - 1801004..1802398 (+) 1395 WP_027480344.1 DUF2336 domain-containing protein -
  DRO_RS08920 (DRO_1754) - 1802448..1802735 (-) 288 WP_027480343.1 hypothetical protein -
  DRO_RS08925 (DRO_1755) - 1802967..1805204 (+) 2238 WP_010888410.1 ATP-dependent helicase -

Sequence

Protein


Download         Length: 1016 a.a.        Molecular weight: 112099.73 Da        Isoelectric Point: 6.4544

>NTDB_id=461033 DRO_RS08905 WP_010888406.1 1797378..1800428(-) (uvrA) [Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539 strain R1]
MQDKLIVRGAREHNLKDITVELPRDRFVVITGVSGSGKSTLAFDTIYAEGQRRYVESLSAYARQFLGLMEKPDVDSITGL
SPAISIDQKTTSHNPRSTVGTVTEIHDYLRLLYARVGTPYCPICGRKIEKQSPSEVTDRLLAGFPDKRAILLAPAVRGRK
GEYKKLFADLRREGYARVRVDGTLYELEEAEKLKLEKFEKHDVDIVIDRLTLRESDRSRIAESVELGIRRGEGLLRVLLP
DAGEDGGAHEELYSEKFACPEHGSVLEELEPRSFSFNSPYGACGDCAGIGAKQEFSPERIIDEKLSIAGGAIIPWTKKGA
DAGIYYWDKLKALAEHLDFDLKTPWKDLPAKAQKAVLHGPGEAFEVVYRRGGKETMRFMTEFEGVITNLERRYADTESEF
MRERLEELMELRPCPTCGGTRYKPEILAVRVGGLNISQTSGMSVLDADAFFQQLQEGELDHAAIEPFLKRHTGGTAKAHG
PLHYEYDLGTFGAAVAAPILRAIRTRLKFLVDVGLDYLSLDRTANTLSGGEAQRIRLATQVGSGLTGVLYVLDEPSIGLH
PKDNGRLIGTLKNLRDLGNSLLVVEHDEDTMLEADYLIDMGPGAGVHGGEVIASGTPEQVKQDKNSLTGKYLRGEMKIEV
PAERRPGNGKFLKVFGARQNNLQDVDVSIPLGTMTVVTGPSGSGKSTLIHDILHATLARELNGAKTTPGLYDRIEGMEQL
DKVIEIDQSPIGRTPRSNPATYTGVFTEIRDLFTRTPEARRRGYQAGRFSFNVKGGRCEHCKGDGVMKIEMNFLPDIYVP
CEVCHGARYNRETLEVKYNHKTIADVLDLTVEDAHEFFEAIPTIERKMQLLLDVGLGYMKIGQPSTTLSGGEAQRIKLAT
ELSKRATGRTIYILDEPTTGLHFEDVRKLMDVLQRLAEGGNTLVIIEHNLDVMKSADYLIDLGPEGGVRGGTVVAVGTPE
EVAAHPTSYTGEYLRKVPGIVAAEPRARGEKAEKPAKAKAPAKKRTKKQTELVEAD

Nucleotide


Download         Length: 3051 bp        

>NTDB_id=461033 DRO_RS08905 WP_010888406.1 1797378..1800428(-) (uvrA) [Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539 strain R1]
ATGCAAGACAAACTCATCGTGCGCGGCGCCCGGGAACACAACCTCAAGGACATCACCGTGGAGCTGCCCCGCGACCGCTT
CGTGGTGATTACCGGCGTGTCGGGCAGCGGCAAGTCCACGCTGGCTTTCGACACCATCTACGCCGAGGGCCAGCGCCGCT
ACGTCGAGTCGCTCAGTGCCTACGCGAGGCAGTTCCTGGGCCTGATGGAAAAGCCCGACGTGGACAGCATCACTGGCCTC
TCGCCGGCCATTTCCATCGACCAGAAGACGACCAGCCACAACCCGCGCAGCACGGTGGGTACCGTCACCGAGATTCACGA
CTACCTGCGCCTGCTCTACGCCCGCGTCGGTACGCCGTATTGCCCCATCTGCGGACGCAAAATCGAAAAGCAGAGCCCCA
GCGAAGTCACCGACCGCCTGCTGGCGGGCTTTCCCGACAAGCGCGCCATCCTGCTCGCCCCGGCGGTGCGCGGACGCAAA
GGCGAGTACAAGAAGCTGTTCGCTGACCTGCGACGTGAGGGCTACGCGCGGGTGCGGGTGGACGGCACGCTCTACGAACT
GGAAGAAGCCGAAAAGCTCAAGCTGGAAAAGTTCGAGAAGCACGACGTGGACATCGTCATCGACCGCCTGACTCTACGTG
AGAGCGACCGCAGCCGCATCGCCGAGTCGGTGGAACTCGGCATCCGGCGCGGCGAGGGCCTGCTGCGGGTGCTGCTGCCC
GACGCGGGTGAGGACGGCGGCGCGCACGAGGAGCTGTACTCCGAGAAGTTCGCCTGCCCCGAACACGGCAGCGTGCTGGA
AGAACTCGAGCCGCGCTCCTTTTCCTTCAACTCGCCCTACGGCGCCTGCGGCGACTGCGCGGGCATCGGGGCCAAGCAGG
AATTCTCGCCCGAGCGCATCATCGACGAAAAACTGAGTATCGCCGGGGGCGCCATCATCCCCTGGACCAAAAAGGGCGCC
GACGCGGGCATTTATTACTGGGACAAGCTCAAGGCGCTGGCCGAGCACCTCGACTTCGACCTGAAAACGCCCTGGAAGGA
CCTGCCCGCGAAGGCGCAAAAAGCCGTGTTGCACGGCCCCGGCGAGGCTTTTGAGGTTGTCTACCGGCGCGGCGGCAAGG
AAACCATGCGCTTCATGACCGAGTTCGAGGGCGTGATCACCAACCTGGAGCGGCGCTACGCCGACACCGAGTCGGAATTC
ATGCGCGAGAGGCTCGAGGAACTCATGGAGCTGCGGCCCTGCCCCACCTGCGGCGGCACCCGCTACAAGCCCGAGATTCT
GGCGGTGCGGGTGGGCGGCCTGAACATCTCGCAGACGAGCGGCATGAGCGTGCTGGACGCCGACGCCTTTTTCCAGCAGT
TGCAGGAAGGCGAACTCGATCACGCGGCCATCGAGCCCTTCCTCAAGCGCCACACCGGCGGCACCGCCAAGGCGCACGGC
CCGCTGCACTACGAGTACGACCTGGGTACGTTCGGCGCGGCGGTGGCGGCCCCGATTCTGCGGGCGATTCGCACCCGGCT
GAAGTTTCTGGTGGACGTGGGGCTCGACTACCTCTCGCTGGACCGCACCGCCAACACGCTCTCGGGCGGCGAGGCGCAGC
GCATCCGGCTGGCGACCCAGGTGGGCAGCGGCCTGACCGGGGTGCTGTACGTGCTCGACGAGCCGTCCATCGGCCTGCAC
CCCAAGGACAACGGGCGACTCATCGGCACGCTGAAGAACCTGCGTGACCTGGGCAACTCGCTGCTGGTGGTGGAGCACGA
CGAGGACACCATGCTGGAGGCCGACTACCTGATCGACATGGGGCCGGGCGCGGGGGTGCACGGCGGCGAAGTCATCGCCT
CGGGCACGCCCGAACAGGTCAAGCAGGACAAGAACAGCCTCACCGGCAAGTACCTGCGCGGCGAGATGAAAATCGAGGTG
CCCGCCGAGCGCCGCCCCGGCAACGGCAAGTTCCTGAAGGTCTTCGGCGCGCGCCAGAACAACTTGCAGGACGTGGACGT
GTCCATTCCGCTCGGCACCATGACGGTGGTGACTGGCCCCTCGGGCAGCGGCAAAAGCACCCTGATTCACGACATCCTGC
ACGCCACGCTGGCCCGCGAACTCAACGGCGCCAAGACCACGCCGGGACTGTACGACCGCATCGAGGGCATGGAGCAGCTG
GACAAGGTCATCGAGATCGACCAGTCGCCCATCGGGCGCACGCCGCGCTCAAATCCGGCGACCTACACGGGCGTGTTCAC
CGAAATCCGTGATTTGTTCACCCGGACTCCCGAGGCGCGGCGGCGCGGGTATCAGGCCGGACGCTTTTCCTTCAACGTCA
AGGGCGGGCGCTGCGAACACTGCAAGGGCGACGGCGTGATGAAGATCGAGATGAACTTCCTGCCCGACATCTACGTGCCC
TGCGAGGTCTGCCACGGGGCGCGCTACAATCGCGAGACGCTGGAGGTCAAGTACAACCACAAGACGATTGCCGACGTGCT
CGACCTGACGGTGGAGGACGCCCACGAGTTTTTTGAGGCGATCCCGACCATCGAGCGCAAGATGCAACTGCTGCTCGACG
TGGGCCTGGGCTACATGAAAATCGGCCAGCCCTCCACCACGCTCTCGGGCGGCGAGGCGCAGCGCATCAAGCTGGCGACC
GAGCTGAGCAAGCGGGCCACCGGGCGCACCATCTACATCCTCGACGAGCCGACCACCGGCCTGCACTTCGAGGACGTGCG
CAAGCTGATGGACGTGCTGCAACGCCTCGCGGAAGGTGGCAACACGCTGGTCATCATCGAGCACAACCTCGACGTGATGA
AGTCGGCGGACTACCTCATCGACCTGGGGCCGGAAGGCGGCGTGCGCGGCGGAACCGTCGTGGCGGTGGGCACACCCGAA
GAAGTCGCTGCCCACCCGACGAGCTACACCGGCGAGTACCTGCGCAAGGTGCCGGGCATCGTGGCCGCCGAGCCGCGTGC
CAGGGGTGAAAAGGCGGAAAAGCCCGCCAAGGCCAAAGCGCCCGCCAAGAAAAGGACCAAGAAGCAGACGGAACTGGTCG
AGGCCGACTGA

Domains

Predicted by InterProScan.

UvrA interaction domain (UvrA_inter)

(131-239)

UvrA DNA-binding domain (UvrA_DNA-bind)

(297-407)

ABC transporter (ABC_tran)

(662-898)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q46577

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

54.388

96.457

0.525
  uvrA Streptococcus pneumoniae TIGR4

54.388

96.457

0.525
  uvrA Streptococcus pneumoniae D39

54.388

96.457

0.525