Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   JL476_RS06520 Genome accession   NZ_CP068586
Coordinates   1248166..1249980 (-) Length   604 a.a.
NCBI ID   WP_002786130.1    Uniprot ID   -
Organism   Campylobacter coli strain CC19CH076     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1243166..1254980
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JL476_RS06495 (JL476_06500) - 1243747..1244352 (-) 606 WP_002789871.1 hypothetical protein -
  JL476_RS06500 (JL476_06505) - 1244595..1244905 (+) 311 Protein_1270 hypothetical protein -
  JL476_RS06505 (JL476_06510) hemE 1245053..1246075 (+) 1023 WP_002789869.1 uroporphyrinogen decarboxylase -
  JL476_RS06510 (JL476_06515) - 1246072..1246974 (+) 903 WP_002777490.1 radical SAM protein -
  JL476_RS06515 (JL476_06520) - 1246971..1248164 (-) 1194 WP_162284664.1 hypothetical protein -
  JL476_RS06520 (JL476_06525) uvrC 1248166..1249980 (-) 1815 WP_002786130.1 excinuclease ABC subunit UvrC Machinery gene
  JL476_RS06525 (JL476_06530) - 1249973..1250449 (-) 477 WP_002777499.1 hypothetical protein -
  JL476_RS06530 (JL476_06535) guaA 1250586..1252121 (+) 1536 WP_002831315.1 glutamine-hydrolyzing GMP synthase -
  JL476_RS06535 (JL476_06540) - 1252296..1252904 (+) 609 WP_002783669.1 class I SAM-dependent methyltransferase -
  JL476_RS06540 (JL476_06545) - 1253027..1253584 (-) 558 WP_002831311.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 604 a.a.        Molecular weight: 69738.69 Da        Isoelectric Point: 9.1096

>NTDB_id=459929 JL476_RS06520 WP_002786130.1 1248166..1249980(-) (uvrC) [Campylobacter coli strain CC19CH076]
MAEILLKNTLKEELQTLPANAGVYQYFNAEGKLLYVGKAKNLKNRVRSYFAFTPNLRANPKNSLRIQKMIEEAVHLEFIT
TNSEADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFNEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYP
LKQKASCKSPCIFYQISRCLAPCDKKITQEEYRLILDKAINALLSPSILVKNLEKQMFHLAQNENYEEAAKIRDQIATIR
DLEIKVEIDIAKLEDFEIFALACESSMLSTLRFVVQNGKIISANSKITPLKNNTDFDKNEIYKQLILENFSVDIPLVANT
VYVYEDFEDRELLEEILSQRFDKKISIKVPKIGEKRRICDLAFQNACLNIQKEQKNSDFNIQKELKNYFELENLPNCIEV
FDNSHLQGVANVGAMITYKMGTWDKSNYRKFHLKYKNDYEQMREVLTRRALEFDKMPAPDLWLIDGGKALLDLAKEIILS
SGANVDILAISKEKIDAKAHRAKGGAKDKIHSLKGEFALSINDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLSSSKLVK
SGLSAGVIQKLLAYYGSFEAIYEANFEELCQLVGKKSAQKIKED

Nucleotide


Download         Length: 1815 bp        

>NTDB_id=459929 JL476_RS06520 WP_002786130.1 1248166..1249980(-) (uvrC) [Campylobacter coli strain CC19CH076]
ATGGCTGAAATTTTACTTAAAAATACTCTCAAAGAAGAGCTTCAAACCCTACCTGCAAATGCTGGAGTGTATCAGTATTT
TAATGCCGAAGGAAAGCTTTTATATGTAGGCAAGGCTAAAAATCTTAAAAACCGCGTAAGATCTTATTTTGCTTTTACCC
CAAATTTACGCGCCAATCCAAAAAATTCTTTAAGAATTCAAAAAATGATAGAAGAAGCGGTGCATTTGGAATTTATTACA
ACAAATTCAGAAGCTGATGCTTTGATTTTGGAAAATTCTTTTATCAAGCAACTTCATCCAAAATACAATATTTTACTAAG
AGATGATAAGACTTATCCTTATATTTATGTAGATTTTAATGAAGAATTTCCGCGTTTTGAAATCACTAGAAAATTAGTTA
AAAAAAGTAAAATCAAATATTTTGGCCCCTTTTTTAAAGGAGCTAGAGAGCTTTTAGATGCGCTTTATTTATACTATCCT
TTAAAGCAAAAAGCAAGTTGTAAATCTCCTTGTATTTTTTATCAAATTTCTCGTTGTCTTGCGCCTTGTGATAAAAAAAT
TACCCAAGAAGAATATCGTTTGATTTTAGATAAAGCTATCAATGCTCTTTTAAGCCCTAGTATTTTAGTGAAAAATTTGG
AAAAACAAATGTTTCATTTAGCCCAAAATGAGAATTATGAAGAAGCGGCAAAAATAAGAGATCAGATTGCTACGATAAGG
GATTTGGAAATTAAAGTTGAGATTGATATCGCTAAATTAGAAGACTTTGAAATTTTTGCTTTAGCTTGTGAAAGCTCTAT
GCTTTCAACTTTGCGTTTTGTGGTGCAAAATGGAAAAATCATCAGCGCTAATTCTAAAATCACTCCGCTTAAAAACAATA
CAGATTTTGATAAAAATGAGATTTATAAACAGCTTATTTTAGAAAATTTTAGCGTAGACATTCCTTTGGTTGCAAATACT
GTTTATGTTTATGAGGATTTTGAAGACAGGGAGCTTTTAGAAGAAATTTTAAGCCAGAGATTTGATAAAAAAATCAGCAT
TAAAGTTCCTAAAATAGGGGAAAAAAGAAGAATTTGTGATTTGGCATTTCAAAATGCGTGTTTAAATATACAAAAAGAGC
AAAAAAATAGTGATTTTAATATACAAAAAGAACTTAAAAATTATTTCGAGCTTGAAAATCTGCCAAATTGTATAGAAGTT
TTTGATAATTCTCATTTGCAAGGTGTGGCGAATGTAGGAGCTATGATAACTTATAAAATGGGTACTTGGGATAAGTCAAA
TTATAGAAAATTTCATTTAAAATACAAAAATGATTATGAGCAAATGCGTGAAGTTTTAACGCGTAGAGCATTAGAATTTG
ACAAAATGCCTGCTCCTGATTTGTGGCTTATAGATGGAGGAAAGGCTTTGCTTGATTTAGCTAAAGAAATCATCTTAAGT
AGTGGGGCAAATGTTGATATTTTAGCAATCTCAAAAGAAAAAATCGATGCTAAAGCTCACCGCGCTAAAGGAGGGGCTAA
AGATAAAATTCACTCTTTAAAAGGAGAATTTGCCCTAAGCATTAACGATAAAAAATTACAATTCTTACAGAAATTAAGAG
ATGAAGCACATCGTTTTGCCATAAGTTTTCATCAAAACACTAAGAAAAAACAAGATTTATCAAGCTCTAAGCTTGTAAAA
TCAGGACTTAGTGCGGGAGTTATACAAAAACTTTTGGCGTATTATGGAAGTTTTGAAGCTATTTATGAGGCAAATTTTGA
AGAATTGTGCCAATTAGTAGGAAAAAAATCAGCACAAAAAATAAAGGAAGATTGA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(21-103)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(387-541)

UvrB/uvrC motif (UVR)

(209-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

46.18

97.517

0.45