Detailed information NTG0459156

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: I6J13_RS06625
• Genome accession: NZ_CP068213
• Coordinates: 1352154..1354712 (-)
• Length: 852 a.a.
• NCBI ID: WP_006269780.1
• Uniprot ID: -
• Organism: Streptococcus constellatus strain FDAARGOS_1156
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1347154..1359712

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J13_RS06600 (I6J13_06600)	-	1347374..1347937 (-)	564	WP_006269774.1	DNA-3-methyladenine glycosylase I	-
I6J13_RS06605 (I6J13_06605)	ruvA	1347949..1348539 (-)	591	WP_006269776.1	Holliday junction branch migration protein RuvA	Machinery gene
I6J13_RS06610 (I6J13_06610)	hexB	1348925..1350871 (-)	1947	WP_006269779.1	DNA mismatch repair endonuclease MutL	Machinery gene
I6J13_RS06615 (I6J13_06615)	brsR	1351118..1351558 (+)	441	WP_006269783.1	LytTR family DNA-binding domain-containing protein	Regulator
I6J13_RS06620 (I6J13_06620)	-	1351555..1352013 (+)	459	WP_003071509.1	DUF3021 domain-containing protein	-
I6J13_RS06625 (I6J13_06625)	hexA	1352154..1354712 (-)	2559	WP_006269780.1	DNA mismatch repair protein MutS	Machinery gene
I6J13_RS06630 (I6J13_06630)	argR	1354875..1355315 (-)	441	WP_003071513.1	arginine repressor	-
I6J13_RS06635 (I6J13_06635)	argS	1355419..1357107 (+)	1689	WP_006269777.1	arginine--tRNA ligase	-
I6J13_RS06640 (I6J13_06640)	-	1357252..1358778 (+)	1527	WP_115342911.1	IS1182 family transposase	-
I6J13_RS06645 (I6J13_06645)	nrdI	1358854..1359309 (-)	456	WP_006269343.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-

Sequence

Protein

• Length: 852 a.a.
• Molecular weight: 96026.50 Da
• Isoelectric Point: 4.9598

>NTDB_id=459156 I6J13_RS06625 WP_006269780.1 1352154..1354712(-) (hexA) [Streptococcus constellatus strain FDAARGOS_1156]
MTKEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAINAAQILEIALTSRNKNSENPIPMAGVPYHSVQQYIDVLI
ESGYKVAIAEQVEDPKKAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVALDKLENLYGLAYMDLVTGEFQVTSLSDFNM
VCGEIRNLRAREVVLGYELPESEHQVLANQMNLLLSQVGTAFEDVQLLGDELSRLEHQVAGKLLEYVHQTQLRELSHLKR
VHHYEIKDFLQMDYATMASLDLTENARTGKKHGSLYWLMDETKTAMGTRLLRRWIQQPLIDKERILKRQDVVQVFLDYFF
ERSDLADSLKGVYDIERLASRVSFGKTNPKDLLQLAATLSNVPQIKGILQGIDHPVLGQLIENLDDIPELANLIQSAISP
DAPNVITEGNIIQTGFDEILDKYRVVMRDGTSWIADIEAKERAASGINNLKIDYNKKDGYYFHVTNSQLEHVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFMRIREEAGKYIKRLQSLAQTLATIDVLQSFAAVAEKQRFVRPEFI
ERPSIEIDKGRHAVVEKVMGAQTYIPNSISMDENVNVQLITGPNMSGKSTYMRQLAIIVIMAQMGSYVSAESAQLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANHAISQATEHSLILFDELGRGTATYDGMALAQAIIEYIHNRTGAKTLFATHYHEL
TDLSTSLTQLENVHVATLEKDGQVTFLHKIEAGPADKSYGIHVAKIAGLPNDLLMRADQILTRLEEQANEKPSLNPSNKG
ANDSKENQVSEQISLFTETTESPILEKLRQLDIYNMTPMEVMLAVSDMKKHL

Nucleotide

• Length: 2559 bp

>NTDB_id=459156 I6J13_RS06625 WP_006269780.1 1352154..1354712(-) (hexA) [Streptococcus constellatus strain FDAARGOS_1156]
ATGACAAAAGAAAAACTATCTCCGGGAATGCAACAGTATTTAGATATAAAAAAAGATTATCCGGATGCTTTTTTGCTATT
TCGCATGGGAGATTTTTATGAATTATTCTATGAAGATGCGATCAATGCAGCACAGATTTTAGAAATTGCTCTGACTAGCC
GTAATAAAAATTCGGAAAATCCAATCCCGATGGCAGGAGTTCCCTACCATTCGGTGCAACAGTATATTGATGTTTTAATT
GAATCGGGCTATAAAGTAGCGATTGCAGAGCAGGTGGAAGATCCTAAAAAAGCAGTTGGTGTAGTCAAACGTGAGGTGGT
ACAAGTCATCACACCGGGGACAGTCGTTGATTCTTCAAAACCAGATAGTCAAAATAATTTCTTGGTAGCTTTAGATAAAC
TAGAAAATTTATATGGGCTGGCTTACATGGACTTGGTTACAGGTGAATTTCAGGTCACAAGTCTTAGTGACTTTAACATG
GTCTGTGGAGAAATTCGGAACTTGCGAGCGCGTGAAGTGGTCTTAGGATATGAATTACCTGAATCAGAGCACCAAGTGTT
GGCAAATCAAATGAATTTGTTATTATCACAGGTGGGAACTGCTTTTGAAGATGTTCAGCTATTAGGGGATGAATTGTCTC
GCTTAGAACATCAAGTAGCTGGAAAACTGTTAGAATATGTTCATCAGACGCAGCTGCGTGAGCTTAGTCACTTAAAGCGA
GTTCATCATTATGAAATCAAGGATTTCTTACAGATGGATTATGCAACCATGGCAAGTCTGGATTTAACAGAGAATGCACG
TACAGGAAAGAAGCACGGTAGTCTGTATTGGCTGATGGATGAGACCAAGACAGCTATGGGGACGCGACTTTTAAGAAGAT
GGATTCAGCAGCCCTTGATTGACAAAGAGCGAATCCTTAAGCGGCAGGATGTCGTGCAGGTATTTCTAGATTATTTTTTT
GAGCGCAGTGATTTAGCAGATAGTCTCAAAGGTGTGTATGACATTGAGCGTTTAGCCAGTCGTGTTTCGTTTGGAAAGAC
CAATCCGAAAGATTTATTGCAGTTGGCGGCAACATTGAGCAATGTCCCTCAGATTAAGGGAATTTTACAAGGAATTGATC
ATCCTGTTTTGGGACAGTTGATTGAAAACTTGGATGACATTCCAGAATTGGCAAACTTGATTCAGTCGGCAATTTCTCCC
GATGCTCCAAATGTTATTACTGAAGGGAATATCATTCAAACTGGTTTTGATGAAATCTTAGATAAATATCGAGTGGTTAT
GCGAGATGGTACGAGCTGGATTGCTGATATCGAAGCGAAAGAAAGGGCGGCTAGTGGGATTAATAATCTAAAAATTGATT
ACAATAAAAAAGATGGTTATTATTTCCATGTTACTAATTCACAGTTGGAGCACGTACCTAGCCACTTTTTCCGAAAAGCA
ACGTTGAAAAATTCAGAACGATTTGGTACAGAGGAATTGGCTCGTATTGAAGGCGAAATGTTGGAAGCGCGTGAAAAATC
TGCTAATTTAGAATATGAGATTTTTATGCGTATTCGTGAAGAAGCTGGCAAATATATCAAGCGTCTGCAATCCTTGGCAC
AAACTCTGGCAACGATTGATGTATTACAAAGTTTTGCAGCAGTTGCTGAAAAGCAACGCTTTGTACGCCCAGAATTTATT
GAACGTCCTTCCATTGAAATTGATAAGGGACGGCATGCGGTTGTAGAAAAGGTCATGGGTGCACAAACCTATATTCCTAA
CAGCATTTCAATGGATGAAAATGTCAACGTTCAGCTAATTACAGGTCCAAATATGAGTGGGAAGTCAACCTATATGCGTC
AATTAGCGATTATTGTTATTATGGCTCAAATGGGTTCCTATGTTTCAGCTGAGAGTGCTCAATTACCAATTTTTGATGCC
ATCTTCACTCGAATTGGTGCGGCAGATGACTTGGTATCTGGACAATCAACCTTTATGGTAGAAATGATGGAAGCAAATCA
TGCTATTTCTCAAGCAACAGAGCACTCTCTTATTCTTTTTGATGAGTTGGGAAGAGGGACAGCGACATATGATGGGATGG
CTCTTGCTCAGGCGATTATTGAATATATCCACAATCGAACAGGGGCAAAGACCCTTTTTGCCACACACTATCATGAGTTG
ACAGACTTGTCAACTAGCTTGACACAGTTAGAAAATGTTCATGTAGCAACTTTAGAAAAAGATGGGCAAGTGACCTTCCT
TCATAAGATTGAAGCTGGTCCTGCGGATAAATCTTATGGGATTCATGTGGCAAAAATTGCAGGTTTACCGAATGATTTGC
TGATGAGAGCAGACCAGATCTTAACACGATTAGAAGAACAAGCAAATGAGAAACCGTCTCTCAATCCTTCTAATAAAGGA
GCTAATGATAGTAAGGAAAATCAAGTATCTGAGCAGATATCTTTATTCACAGAAACAACTGAATCCCCTATTTTAGAAAA
ATTACGTCAGTTGGACATCTATAACATGACTCCAATGGAAGTGATGCTGGCTGTATCAGATATGAAAAAACATCTCTGA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (255-546)

• MutS domain II (MutS_II) (126-239)

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (599-785)

• MutS family domain IV (MutS_IV) (415-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	75.939	100	0.759
mutS	Pseudomonas stutzeri strain ATCC 17587	36.806	100	0.373