Detailed information NTG0458767

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: I6J12_RS01125
• Genome accession: NZ_CP068060
• Coordinates: 224805..225860 (+)
• Length: 351 a.a.
• NCBI ID: WP_003035215.1
• Uniprot ID: I0SHB2
• Organism: Streptococcus anginosus strain FDAARGOS_1155
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 219805..230860

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J12_RS01095 (I6J12_01095)	-	220325..220960 (-)	636	WP_003035211.1	YigZ family protein	-
I6J12_RS01100 (I6J12_01100)	comFA/cflA	221017..222318 (+)	1302	WP_003035191.1	DEAD/DEAH box helicase	Machinery gene
I6J12_RS01105 (I6J12_01105)	comFC/cflB	222315..222980 (+)	666	WP_003035196.1	ComF family protein	Machinery gene
I6J12_RS01110 (I6J12_01110)	hpf	223059..223601 (+)	543	WP_003035226.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
I6J12_RS01115 (I6J12_01115)	rsmD	223789..224337 (+)	549	WP_195190375.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
I6J12_RS01120 (I6J12_01120)	coaD	224327..224824 (+)	498	WP_003025749.1	pantetheine-phosphate adenylyltransferase	-
I6J12_RS01125 (I6J12_01125)	sepM	224805..225860 (+)	1056	WP_003035215.1	SepM family pheromone-processing serine protease	Regulator
I6J12_RS01130 (I6J12_01130)	-	225998..226561 (+)	564	WP_003035207.1	YutD family protein	-
I6J12_RS01135 (I6J12_01135)	rlmN	226595..227677 (+)	1083	WP_042752888.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
I6J12_RS01140 (I6J12_01140)	-	227670..228200 (+)	531	WP_003035190.1	VanZ family protein	-
I6J12_RS01145 (I6J12_01145)	-	228408..229759 (+)	1352	WP_148290573.1	IS3 family transposase	-

Sequence

Protein

• Length: 351 a.a.
• Molecular weight: 38352.32 Da
• Isoelectric Point: 10.1906

>NTDB_id=458767 I6J12_RS01125 WP_003035215.1 224805..225860(+) (sepM) [Streptococcus anginosus strain FDAARGOS_1155]
MEKPRNKFKKWPIIAVVGLILLFLSFVVPLPYYIEVPGGAADVRQVLRVDNKEDKEKGSYNFVTVGIQHATFAHLVYAWL
TPFTDIYSAKDLTGGTSDKEYMRINQFYMETSQNLAKYQGLKKAGKDITLKYLGVYVLQVTKNSTFKGILNIADTVTGVN
DKTFNSSKELIDYVGAQKIGSKVKVNYVEDGQKKSATGKIIKLENGKNGIGISLIDRTEVTSNTPIEFSTAGIGGPSAGL
MFSLAIYTQIADPTLRDGRNIAGTGSIDREGKVGDIGGIDKKVVSAAKNGAEIFFAPNNPVTKEVKKSNPKAKTNYETAL
AAAKKIKTKMKIIPVKTLQDAIDYLKSTKKS

Nucleotide

• Length: 1056 bp

>NTDB_id=458767 I6J12_RS01125 WP_003035215.1 224805..225860(+) (sepM) [Streptococcus anginosus strain FDAARGOS_1155]
ATGGAAAAACCAAGAAATAAATTTAAAAAATGGCCGATAATTGCAGTAGTAGGGCTGATTTTGCTTTTCTTATCTTTTGT
AGTTCCCTTGCCTTATTATATTGAGGTGCCAGGTGGTGCAGCGGATGTCCGTCAGGTATTGCGCGTGGACAACAAAGAAG
ATAAGGAAAAAGGTTCTTATAATTTTGTAACGGTTGGGATTCAGCATGCGACCTTCGCTCATTTGGTTTATGCTTGGCTG
ACTCCTTTTACAGATATTTATTCGGCGAAGGATTTGACTGGCGGAACTTCTGATAAAGAATACATGCGGATCAATCAGTT
TTATATGGAAACGTCGCAAAACCTAGCTAAATACCAAGGCTTGAAAAAAGCTGGCAAAGACATTACTCTGAAATATCTAG
GGGTTTACGTCTTGCAAGTCACAAAGAATTCTACTTTTAAAGGTATTTTAAATATTGCAGATACCGTGACAGGTGTGAAT
GATAAGACTTTCAATAGTTCAAAAGAATTGATAGACTATGTCGGAGCGCAAAAGATTGGCAGCAAGGTCAAGGTGAACTA
TGTAGAAGACGGTCAGAAGAAATCTGCTACAGGTAAAATTATTAAACTTGAAAATGGAAAAAACGGGATTGGCATTAGCT
TGATTGACCGAACAGAAGTCACAAGTAACACACCAATTGAATTTTCAACTGCCGGTATTGGTGGACCAAGTGCGGGCTTG
ATGTTTAGTTTGGCAATTTATACGCAAATTGCAGATCCAACATTGAGAGACGGCAGAAATATTGCTGGGACGGGCTCAAT
TGACCGCGAAGGAAAAGTTGGCGACATTGGTGGGATTGACAAAAAAGTTGTTTCAGCAGCTAAAAATGGCGCAGAAATTT
TCTTTGCGCCAAATAATCCAGTCACCAAGGAAGTGAAAAAATCCAATCCTAAAGCGAAAACAAACTATGAGACAGCTTTG
GCAGCTGCTAAAAAAATTAAAACTAAAATGAAAATTATACCTGTCAAGACCTTGCAAGACGCAATTGATTACCTCAAGAG
CACAAAAAAGTCGTAA

Domains

Predicted by InterProScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (234-307)

• PDZ domain (PDZ_2) (133-197)

3D structure

• AlphaFold DB: I0SHB2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	64.223	97.151	0.624