Detailed information NTG0456951

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: HUW68_RS13930
• Genome accession: NZ_CP055225
• Coordinates: 2770700..2771587 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus LAC
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2765700..2776587

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HUW68_RS13900 (HUW68_13905)	-	2765719..2765811 (+)	93	WP_010956583.1	hypothetical protein	-
HUW68_RS13905 (HUW68_13910)	-	2765919..2766416 (-)	498	WP_001065268.1	glutathione peroxidase	-
HUW68_RS13910 (HUW68_13915)	-	2766426..2766686 (-)	261	WP_001789910.1	hypothetical protein	-
HUW68_RS13915 (HUW68_13920)	-	2767068..2767181 (-)	114	WP_001791776.1	hypothetical protein	-
HUW68_RS13920 (HUW68_13925)	-	2767840..2769840 (-)	2001	WP_000776751.1	ABC transporter permease	-
HUW68_RS13925 (HUW68_13930)	-	2769837..2770592 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
HUW68_RS13930 (HUW68_13935)	braS	2770700..2771587 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
HUW68_RS13935 (HUW68_13940)	braR	2771598..2772263 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
HUW68_RS13940 (HUW68_13945)	-	2772289..2772489 (-)	201	WP_000604728.1	hypothetical protein	-
HUW68_RS13945 (HUW68_13950)	-	2772687..2774111 (+)	1425	WP_000953744.1	alkaline phosphatase	-
HUW68_RS14575	-	2774171..2774272 (-)	102	WP_000731972.1	SE2200 family small protein	-
HUW68_RS13955 (HUW68_13960)	-	2774394..2774849 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
HUW68_RS13960 (HUW68_13965)	-	2775094..2775855 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=456951 HUW68_RS13930 WP_000143419.1 2770700..2771587(-) (braS) [Staphylococcus aureus LAC]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=456951 HUW68_RS13930 WP_000143419.1 2770700..2771587(-) (braS) [Staphylococcus aureus LAC]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997