Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   JCR30_RS07985 Genome accession   NZ_CP067008
Coordinates   1560762..1563590 (-) Length   942 a.a.
NCBI ID   WP_011054967.1    Uniprot ID   P0CZ41
Organism   Streptococcus pyogenes strain iGAS426     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1555762..1568590
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JCR30_RS07955 (JCR30_07955) - 1556438..1557403 (+) 966 WP_002988504.1 LacI family DNA-binding transcriptional regulator -
  JCR30_RS07960 (JCR30_07960) nusB 1557544..1557996 (-) 453 WP_200274634.1 transcription antitermination factor NusB -
  JCR30_RS07965 (JCR30_07965) - 1557989..1558378 (-) 390 WP_002993228.1 Asp23/Gls24 family envelope stress response protein -
  JCR30_RS07970 (JCR30_07970) efp 1558424..1558981 (-) 558 WP_002988496.1 elongation factor P -
  JCR30_RS07975 (JCR30_07975) - 1559077..1559538 (-) 462 WP_002988493.1 deaminase -
  JCR30_RS07980 (JCR30_07980) - 1559573..1560646 (-) 1074 WP_011888618.1 Xaa-Pro peptidase family protein -
  JCR30_RS07985 (JCR30_07985) uvrA 1560762..1563590 (-) 2829 WP_011054967.1 excinuclease ABC subunit UvrA Machinery gene
  JCR30_RS07990 (JCR30_07990) - 1563793..1564737 (+) 945 WP_011888617.1 magnesium transporter CorA family protein -
  JCR30_RS07995 (JCR30_07995) - 1564870..1565526 (+) 657 WP_002983144.1 DUF1129 domain-containing protein -
  JCR30_RS08000 (JCR30_08000) rpsR 1565657..1565896 (-) 240 WP_002983142.1 30S ribosomal protein S18 -
  JCR30_RS08005 (JCR30_08005) ssbA 1566061..1566552 (-) 492 WP_002993238.1 single-stranded DNA-binding protein Machinery gene
  JCR30_RS08010 (JCR30_08010) rpsF 1566574..1566864 (-) 291 WP_002983117.1 30S ribosomal protein S6 -
  JCR30_RS08015 (JCR30_08015) - 1567037..1567330 (-) 294 WP_002983113.1 hypothetical protein -

Sequence

Protein


Download         Length: 942 a.a.        Molecular weight: 104034.22 Da        Isoelectric Point: 6.0690

>NTDB_id=456814 JCR30_RS07985 WP_011054967.1 1560762..1563590(-) (uvrA) [Streptococcus pyogenes strain iGAS426]
MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL
SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPIVRRKK
GQHKTIFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRLFDSVEAALRLGDGYLMIDTMDG
NELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVVPDPSKSLKEGALAPWNPISSNYYPTML
EQAMASFGVDMDTPFEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYTRNVMRGYM
NELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELELTENESTIAKPIVKEIHDRLTFLNNVGLNYL
TLSRAAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLI
DVGPGAGEFGGEIIASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNLQSLDVRFPLGKFIAVT
GVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHIERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALVFF
SAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYILDEPTTGLHTDDIARLLKVLERFVD
DGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQIVATGTPEEVAQVKESYTGHYLKVKLQQ

Nucleotide


Download         Length: 2829 bp        

>NTDB_id=456814 JCR30_RS07985 WP_011054967.1 1560762..1563590(-) (uvrA) [Streptococcus pyogenes strain iGAS426]
ATGCAAAATAAAATAATAATTCATGGGGCAAGAGCCCACAATTTAAAAAATATTGACGTGGAAATTCCACGAGACAAATT
AGTTGTCGTGACAGGGTTATCAGGGTCAGGAAAATCTAGTCTAGCCTTTGATACTATTTATGCGGAAGGGCAACGTCGTT
ACGTAGAAAGTTTATCAGCTTATGCTAGACAGTTCTTGGGTAATATGGAAAAACCAGATGTGGATTCCATTGACGGTCTT
AGCCCTGCTATTTCCATTGATCAAAAAACTACCAGTAAGAACCCCCGCTCAACGGTTGGTACGGTGACTGAAATCAATGA
TTATTTACGTTTACTATATGCGCGTGTGGGCACACCTTACTGTATTAATGGGCATGGGGCCATTACAGCATCTTCTGCAG
AACAAATTGTAGAACAGGTCTTAGCCCTCCCTGAACGGACACGCATGCAGATTTTAGCGCCTATTGTTCGCCGGAAAAAA
GGTCAACACAAAACCATTTTTGAGAAAATTCAAAAAGATGGTTATGTCCGTGTGCGGGTTGATGGGGATATTTTTGACGT
GACAGAAGTGCCGGAGCTGTCAAAAAGTAAGATGCACAACATCGAGGTGGTTATTGATCGTCTGGTTAATAAGGATGGTA
TTCGTAGCCGTTTATTTGATTCGGTTGAAGCAGCTTTAAGGCTGGGAGATGGCTACCTTATGATTGACACTATGGATGGC
AATGAACTGCTCTTTTCTGAGCATTATTCCTGTCCTGTCTGTGGGTTTACGGTTCCTGAATTAGAACCAAGACTCTTCTC
TTTTAATGCGCCGTTCGGCTCTTGTCCGACCTGTGATGGGCTAGGCATTAAGTTGGAAGTGGATTTGGACTTGGTTGTTC
CTGACCCAAGTAAGTCTTTGAAAGAGGGAGCTTTGGCGCCTTGGAATCCTATTTCCTCCAATTATTACCCAACCATGCTT
GAGCAAGCTATGGCAAGTTTTGGGGTGGATATGGATACACCTTTTGAGGCCTTGACTGAGGAAGAAAGGGATTTAGTTCT
TTATGGTTCAGGGGATAGAGAATTTCATTTTCACTATGTGAATGATTTTGGTGGTGAGCGTAACATTGACATTCCTTTTG
AAGGTGTTGTGACTAATGTTAATCGCCGTTATCACGAAACTAATAGTGATTATACGCGCAATGTGATGCGTGGTTATATG
AACGAATTGACCTGTGCGACTTGTCATGGTTACCGTTTGAATGACCAAGCCTTGTGTGTGCATGTGGGTGGCGAAGAAGG
ACCTCATATTGGTCAAATTTCAGAATTATCGATTGCCGACCACTTGCAGTTGTTGGAAGAACTGGAACTCACAGAAAATG
AAAGTACCATTGCTAAACCGATTGTCAAAGAAATTCATGACCGCCTGACCTTCTTAAATAATGTGGGACTGAATTATCTG
ACCTTATCACGTGCTGCTGGGACTTTATCAGGTGGGGAAAGTCAACGAATCAGGTTAGCGACACAGATTGGTTCTAACTT
ATCAGGGGTGCTCTATATCTTGGATGAGCCTTCTATTGGATTGCACCAAAGAGACAATGACCGTTTGATCGAAAGCCTGA
AAAAAATGCGTGATTTGGGTAATACCTTAATTGTGGTAGAACACGATGAAGACACCATGATGCAGGCAGACTGGCTGATT
GATGTGGGGCCTGGGGCAGGTGAGTTCGGTGGAGAAATTATTGCCTCTGGAACGCCGAAACAAGTGGCTAAGAATAAAAA
ATCCATCACGGGTCAATATTTGTCTGGAAAAAAATTCATTCCAGTGCCATTAGAGCGTCGTTCTGGTAATGGCCGATTCA
TTGAAATAAAAGGAGCAGCGCAGAATAATCTTCAAAGCCTCGACGTGAGATTCCCACTGGGTAAATTTATTGCGGTCACA
GGGGTATCAGGCTCAGGGAAATCAACCTTGGTTAATAGTATTTTGAAAAAGGCTGTCGCCCAAAAATTAAACCGTAATGC
TGATAAGCCTGGTAAATATCACTCTATTTCTGGTATTGAACATATTGAACGCTTGATTGACATTGACCAAAGTCCGATTG
GAAGGACGCCACGGTCAAATCCAGCCACCTATACGGGTGTCTTTGATGATATTCGAGACTTGTTTGCCCAAACCAACGAA
GCTAAGATTCGTGGCTACAAAAAAGGCCGTTTCTCTTTTAATGTCAAAGGTGGGCGTTGTGAGGCTTGTTCAGGTGATGG
GATTATCAAAATCGAAATGCACTTTTTGCCAGATGTTTATGTGCCTTGTGAGGTTTGCCACGGCAGACGGTATAATTCTG
AGACGCTTGAGGTGCATTATAAAGAAAAAAATATTGCTGAAGTGCTTGACATGACTGTCGATGATGCCTTGGTATTTTTC
TCTGCTATCCCTAAAATTGCCCGAAAAATTCAAACCATTAAGGATGTTGGTTTGGGTTATGTGACCTTGGGTCAACCAGC
TACTACTCTATCTGGAGGAGAAGCGCAGCGGATGAAATTAGCTAGTGAATTGCACAAACGCTCGACAGGTAAGAGCTTGT
ATATCCTAGATGAGCCAACGACTGGTTTACACACAGATGATATTGCAAGGCTATTAAAAGTTTTGGAACGCTTTGTAGAC
GATGGTAATACGGTTCTTGTGATTGAGCATAATTTGGACGTTATCAAATCTGCTGACCATATTATTGACTTAGGACCAGA
AGGTGGTGTCGGAGGTGGTCAAATTGTTGCCACGGGGACACCAGAAGAGGTAGCTCAAGTTAAAGAAAGCTATACTGGTC
ATTATTTGAAAGTAAAACTACAACAATAG

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(624-860)

UvrA interaction domain (UvrA_inter)

(132-238)

UvrA DNA-binding domain (UvrA_DNA-bind)

(288-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0CZ41

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

84.82

100

0.848
  uvrA Streptococcus pneumoniae TIGR4

84.82

100

0.848
  uvrA Streptococcus pneumoniae D39

84.82

100

0.848